General Information of the Compound
Compound ID
CP0567130
Compound Name
(4R)-N-[(3,5-dichlorophenyl)methyl]-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanamide
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Structure
Formula
C31H45Cl2NO3
Molecular Weight
550.611
Canonical SMILES
C[C@H](CCC(=O)NCc1cc(Cl)cc(Cl)c1)[C@H]1CC[C@H]2[C@@H]3[C@@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
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InChI
InChI=1S/C31H45Cl2NO3/c1-18(4-7-28(37)34-17-19-12-21(32)16-22(33)13-19)24-5-6-25-29-26(9-11-31(24,25)3)30(2)10-8-23(35)14-20(30)15-27(29)36/h12-13,16,18,20,23-27,29,35-36H,4-11,14-15,17H2,1-3H3,(H,34,37)/t18-,20+,23-,24-,25+,26+,27+,29+,30+,31-/m1/s1
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InChIKey
XABGOCPPRYETHH-MBMYFEABSA-N
Physicochemical Property
logP
7.0165
Rotatable Bonds
6
Heavy Atom Count
37
Polar Areas
69.56
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
3
Complexity
37

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 137659458
ChEMBL ID
CHEMBL4097881
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01786, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000088 Flp-In-293 Homo sapiens (Human)  1
1
IC50 > 30000 nM
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