| Compound ID |
Compound Name |
Compound Formula |
|
CP0317631
|
N-[2,5-difluoro-4-[2-[[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]amino]pyridin-4-yl]oxyphenyl]-3-(4-fluorophenyl)-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide
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|
C36H39F3N8O5
|
1
|
| 1 |
IC50 = 3.2 nM
|
|
|
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CP0563520
|
1-cyclopentyl-N-[3-fluoro-4-[2-[[2-(1-methylpiperidin-4-yl)acetyl]amino]pyridin-4-yl]oxyphenyl]-3-(4-fluorophenyl)-2,4-dioxopyrimidine-5-carboxamide
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|
C35H36F2N6O5
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
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CP0557698
|
N-[2-fluoro-4-[2-[[2-(1-methylpiperidin-4-yl)acetyl]amino]pyridin-4-yl]oxyphenyl]-3-(4-fluorophenyl)-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide
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|
C33H34F2N6O5
|
1
|
| 1 |
IC50 = 8.1 nM
|
|
|
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CP0564219
|
3-(4-fluorophenyl)-N-[4-[2-[[2-(1-methylpiperidin-4-yl)acetyl]amino]pyridin-4-yl]oxyphenyl]-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide
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|
C33H35FN6O5
|
1
|
| 1 |
IC50 = 9.8 nM
|
|
|
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CP0553502
|
N-[2,5-difluoro-4-[2-[[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]amino]pyridin-4-yl]oxyphenyl]-2,5-dioxo-1-phenyl-7,8-dihydro-6H-quinoline-3-carboxamide
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|
C38H39F2N7O5
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
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CP0557697
|
N-[4-[6-(cyclopropanecarbonylamino)pyrimidin-4-yl]oxyphenyl]-3-(4-fluorophenyl)-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide
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|
C28H25FN6O5
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0553501
|
1-cyclopentyl-3-(4-fluorophenyl)-N-[4-[6-[[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]amino]pyrimidin-4-yl]oxyphenyl]-2,4-dioxopyrimidine-5-carboxamide
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|
C37H42FN9O5
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0554516
|
1-cyclopropyl-N-[3-fluoro-4-[2-[[2-(1-methylpiperidin-4-yl)acetyl]amino]pyridin-4-yl]oxyphenyl]-3-(4-fluorophenyl)-2,4-dioxopyrimidine-5-carboxamide
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|
C33H32F2N6O5
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
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CP0553500
|
3-(4-fluorophenyl)-N-[4-[6-[[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]amino]pyrimidin-4-yl]oxyphenyl]-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide
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|
C35H40FN9O5
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0543363
|
N-[4-[6-(azetidine-1-carbonylamino)pyrimidin-4-yl]oxyphenyl]-3-(4-fluorophenyl)-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide
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|
C28H26FN7O5
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
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CP0563666
|
N-[4-[2-[[2-(dimethylamino)acetyl]amino]pyridin-4-yl]oxyphenyl]-3-(4-fluorophenyl)-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide
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|
C29H29FN6O5
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
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CP0388620
|
methyl N-[4-[7-amino-3-(3,4-dimethoxyphenyl)-5-(1-methylpiperidin-4-yl)oxypyrazolo[1,5-a]pyrimidin-6-yl]phenyl]carbamate
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|
C28H32N6O5
|
1
|
| 1 |
IC50 = 86 nM
|
|
|
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CP0554517
|
3-(4-fluorophenyl)-2,4-dioxo-1-propan-2-yl-N-[4-[6-(pyrrolidine-1-carbonylamino)pyrimidin-4-yl]oxyphenyl]pyrimidine-5-carboxamide
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|
C29H28FN7O5
|
1
|
| 1 |
IC50 = 86 nM
|
|
|
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CP0563667
|
3-(4-fluorophenyl)-N-[4-[6-[(3-hydroxyazetidine-1-carbonyl)amino]pyrimidin-4-yl]oxyphenyl]-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide
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|
C28H26FN7O6
|
1
|
| 1 |
IC50 = 113 nM
|
|
|
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CP0317628
|
3-(4-fluorophenyl)-N-[4-[6-[[3-(methylamino)azetidine-1-carbonyl]amino]pyrimidin-4-yl]oxyphenyl]-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide
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|
C29H29FN8O5
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
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CP0317629
|
3-(4-fluorophenyl)-2,4-dioxo-1-propan-2-yl-N-[4-[6-[(3-pyrrolidin-1-ylazetidine-1-carbonyl)amino]pyrimidin-4-yl]oxyphenyl]pyrimidine-5-carboxamide
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|
C32H33FN8O5
|
1
|
| 1 |
IC50 = 157 nM
|
|
|
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CP0566934
|
1-cyclopropyl-3-(4-fluorophenyl)-N-[4-[6-[[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]amino]pyrimidin-4-yl]oxyphenyl]-2,4-dioxopyrimidine-5-carboxamide
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|
C35H38FN9O5
|
1
|
| 1 |
IC50 = 304 nM
|
|
|
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CP0570986
|
3-(4-fluorophenyl)-1-methyl-N-[4-[6-[[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]amino]pyrimidin-4-yl]oxyphenyl]-2,4-dioxopyrimidine-5-carboxamide
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|
C33H36FN9O5
|
1
|
| 1 |
IC50 = 321 nM
|
|
|
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CP0385508
|
2-[4-[4-[6-[(2R)-2-(3-fluorophenyl)pyrrolidin-1-yl]imidazo[1,2-b]pyridazin-3-yl]pyridin-2-yl]piperazin-1-yl]acetic acid
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|
C27H28FN7O2
|
1
|
| 1 |
IC50 = 4700 nM
|
|
|
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CP0061016
|
3-(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-phenol
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|
C17H18N4O
|
1
|
| 1 |
IC50 = 4900 nM
|
|
|
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CP0385511
|
1-[4-[6-[(2R)-2-(3-fluorophenyl)pyrrolidin-1-yl]imidazo[1,2-b]pyridazin-3-yl]pyridin-2-yl]piperidin-4-ol
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|
C26H27FN6O
|
1
|
| 1 |
IC50 = 5100 nM
|
|
|
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CP0388864
|
4-[6-(benzylamino)imidazo[1,2-b]pyridazin-3-yl]benzonitrile
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|
C20H15N5
|
1
|
| 1 |
IC50 = 5400 nM
|
|
|
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CP0418567
|
3-[4-amino-7-[3-(hydroxymethyl)cyclobutyl]pyrrolo[2,3-d]pyrimidin-5-yl]phenol
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|
C17H18N4O2
|
1
|
| 1 |
IC50 = 5500 nM
|
|
|
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CP0388616
|
3-(3,4-dimethoxyphenyl)-5-(1-methylpiperidin-4-yl)oxy-6-phenylpyrazolo[1,5-a]pyrimidin-7-amine
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|
C26H29N5O3
|
1
|
| 1 |
IC50 > 11000 nM
|
|
|
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CP0138866
|
1-[4-[3-[4-amino-5-(2-fluoro-5-hydroxyphenyl)pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl]piperazin-1-yl]ethanone
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|
C22H25FN6O2
|
1
|
| 1 |
IC50 > 11000 nM
|
|
|
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CP0388615
|
3-(3,4-dimethoxyphenyl)-5-(1-methylpiperidin-4-yl)oxy-6-(1,3-thiazol-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C23H26N6O3S
|
1
|
| 1 |
IC50 > 8700 nM
|
|
|
