Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-(4-fluorophenyl)-2,4-dioxo-1-propan-2-yl-N-[4-[6-(pyrrolidine-1-carbonylamino)pyrimidin-4-yl]oxyphenyl]pyrimidine-5-carboxamide
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Canonical SMILES
CC(C)n1cc(C(=O)Nc2ccc(Oc3cc(NC(=O)N4CCCC4)ncn3)cc2)c(=O)n(-c2ccc(F)cc2)c1=O
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Compound Formula C29H28FN7O5
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase Mer
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Axl family
Uniprot ID
Q12866
Gene Name
MERTK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 86 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 28 nM