Brief Information of the Cell Line and Protein
Cell Line ID: CL000068 , A-549
 Cell Line Info 
Synonyms
A 549
A549
NCI-A549
A549/ATCC
A549 ATCC
A549ATCC
hA549
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0023
Protein ID: PT01902 , Serine-protein kinase ATM
 Protein Info 
Gene Name ATM
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID Q13315
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000068
 Cell Line Info 
 Protein ID: PT01902
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0127298
 Compound Info 
US9428503, 1
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C26H31N5O3
  1
1
IC50 = 0.22 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0543231
 Compound Info 
1-[2-(3-fluoroazetidin-1-yl)ethyl]-3-[4-[1-(2-methoxyethyl)-3-methyl-2-oxoimidazo[4,5-c]quinolin-8-yl]phenyl]urea
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C26H29FN6O3
  1
1
IC50 = 0.32 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0570533
 Compound Info 
1-[2-(dimethylamino)ethyl]-3-[3-fluoro-4-[1-(2-methoxyethyl)-3-methyl-2-oxoimidazo[4,5-c]quinolin-8-yl]phenyl]urea
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C25H29FN6O3
  1
1
IC50 = 0.65 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0579910
 Compound Info 
1-[2-(dimethylamino)ethyl]-3-[2-fluoro-4-[1-(2-methoxyethyl)-3-methyl-2-oxoimidazo[4,5-c]quinolin-8-yl]phenyl]urea
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C25H29FN6O3
  1
1
IC50 = 0.71 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0579538
 Compound Info 
1-[2-(azetidin-1-yl)ethyl]-3-[4-[1-(2-methoxyethyl)-3-methyl-2-oxoimidazo[4,5-c]quinolin-8-yl]phenyl]urea
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C26H30N6O3
  1
1
IC50 = 0.92 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0579833
 Compound Info 
1-[2-(dimethylamino)ethyl]-3-[4-[1-(2-methoxyethyl)-3-methyl-2-oxoimidazo[4,5-c]quinolin-8-yl]phenyl]-1-methylurea
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C26H32N6O3
  1
1
IC50 = 1.33 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0571170
 Compound Info 
1-[2-(dimethylamino)ethyl]-3-[4-[1-(2-methoxyethyl)-3-methyl-2-oxoimidazo[4,5-c]quinolin-8-yl]phenyl]urea
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C25H30N6O3
  1
1
IC50 = 1.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0580064
 Compound Info 
1-[2-(3,3-difluoroazetidin-1-yl)ethyl]-3-[4-[1-(2-methoxyethyl)-3-methyl-2-oxoimidazo[4,5-c]quinolin-8-yl]phenyl]urea
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C26H28F2N6O3
  1
1
IC50 = 3.31 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS