Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[2-(3,3-difluoroazetidin-1-yl)ethyl]-3-[4-[1-(2-methoxyethyl)-3-methyl-2-oxoimidazo[4,5-c]quinolin-8-yl]phenyl]urea
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Canonical SMILES
COCCn1c2c(cnc3ccc(cc23)-c2ccc(NC(=O)NCCN3CC(F)(F)C3)cc2)n(C)c1=O
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Compound Formula C26H28F2N6O3
Compound Structure
Protein Name
 Protein Info 
Serine-protein kinase ATM
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Atypical protein kinase group
>
Atypical protein kinase PIKK family
Uniprot ID
Q13315
Gene Name
ATM
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 3.31 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 < 1 nM