Brief Information of the Cell Line and Protein
Cell Line ID: CL000065 , HEK293-EBNA
Synonyms
293 c18
293c18
HEK 293 c18
HEK-293 c18
HEK293-EBNA1
HEK-293-EBNA
HEK 293-EBNA
HEK 293 EBNA
HEK293EBNA
293 EBNA
293-EBNA1
293-EBNA
293/EBNA
293EBNA
EBNA-293
EBNA293
293E
HEK293E
HEK/EBNA
HEK-EBNA
HEK.EBNA
293/EBNA-1
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_6974
Protein ID: PT01839 , Vasopressin V1a receptor
Gene Name AVPR1A
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P37288
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000065  Protein ID: PT01839
 
Compound ID Compound Name Compound Formula
CP0177122
(2S)-5-amino-2-{[(2S)-1-{[(4R,7S,10S,13S,16R)-13-[(2S)-butan-2-yl]-7-(carbamoylmethyl)-16-[(4-ethoxyphenyl)methyl]-10-[(1R)-1-hydroxyethyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)pentanamide
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C43H67N11O12S2
 1
1
Ki = 0.63 nM
   TI
   LI
   LO
   TS
CP0302223
(Z)-3-(4-(N-(4-chlorophenyl)-N-(2-oxo-2-(2-(2-oxoindolin-3-ylidene)hydrazinyl)ethyl)sulfamoyl)phenyl)-N-(3-(dimethylamino)propyl)propanamide
   Show/Hide
C30H33ClN6O5S
 1
1
Ki = 42 nM
   TI
   LI
   LO
   TS
CP0198143
CHEMBL2113201
   Show/Hide
C27H28ClN5O5S
 1
1
Ki = 65 nM
   TI
   LI
   LO
   TS
CP0393401
2-[N-(benzenesulfonyl)-4-methoxyanilino]-N-(4-chloro-2-methylphenyl)acetamide
   Show/Hide
C22H21ClN2O4S
 1
1
Ki = 70 nM
   TI
   LI
   LO
   TS
CP0483645
3-[4-[(4-chlorophenyl)-[2-[(2-hydroxy-1H-indol-3-yl)diazenyl]-2-oxoethyl]sulfamoyl]phenyl]-N-(3-hydroxypropyl)propanamide
   Show/Hide
C28H28ClN5O6S
 1
1
Ki = 94 nM
   TI
   LI
   LO
   TS
CP0224226
N-[2-(3,4-dihydro-1H-isoquinolin-2-yl)-2-oxoethyl]-N-(4-methoxyphenyl)benzenesulfonamide
   Show/Hide
C24H24N2O4S
 1
1
Ki = 115 nM
   TI
   LI
   LO
   TS
CP0377968
CHEMBL2113185
   Show/Hide
C28H28ClN5O6S
 1
1
Ki = 133 nM
   TI
   LI
   LO
   TS
CP0198144
2-(4-chloro-N-[4-[2-(dimethylamino)ethoxy]phenyl]sulfonylanilino)-N-[(2-hydroxy-1H-indol-3-yl)imino]acetamide
   Show/Hide
C26H26ClN5O5S
 1
1
Ki = 176 nM
   TI
   LI
   LO
   TS
CP0107768
2-[Benzenesulfonyl-(4-methoxy-phenyl)-amino]-N-(3-chloro-2-methyl-phenyl)-acetamide
   Show/Hide
C22H21ClN2O4S
 1
1
Ki = 300 nM
   TI
   LI
   LO
   TS
CP0480328
N-[2-(3,4-dihydro-1H-isoquinolin-2-yl)-2-oxoethyl]-N-(4-methylphenyl)benzenesulfonamide
   Show/Hide
C24H24N2O3S
 1
1
Ki = 325 nM
   TI
   LI
   LO
   TS
CP0467144
CHEMBL2113215
   Show/Hide
C24H22N4O5S
 1
1
Ki = 437 nM
   TI
   LI
   LO
   TS
CP0303775
CHEMBL2113198
   Show/Hide
C24H21ClN4O5S
 1
1
Ki = 471 nM
   TI
   LI
   LO
   TS
CP0464488
2-(4-chloro-N-thiophen-2-ylsulfonylanilino)-N-[(2-hydroxy-1H-indol-3-yl)imino]acetamide
   Show/Hide
C20H15ClN4O4S2
 1
1
Ki = 510 nM
   TI
   LI
   LO
   TS
CP0049593
2-(4-chloro-N-[4-[2-(2-methoxyethoxy)ethoxy]phenyl]sulfonylanilino)-N-[(2-hydroxy-1H-indol-3-yl)imino]acetamide
   Show/Hide
C27H27ClN4O7S
 1
1
Ki = 511 nM
   TI
   LI
   LO
   TS
CP0441813
2-(2-(4-ethoxy-N-(4-methoxyphenyl)phenylsulfonamido)acetyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
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C27H29N3O6S
 1
1
Ki = 570 nM
   TI
   LI
   LO
   TS
CP0250765
CHEMBL2113177
   Show/Hide
C28H29ClN6O5S
 1
1
Ki = 582 nM
   TI
   LI
   LO
   TS
CP0889531
N-(4-chlorophenyl)-3,4-dimethoxy-N-{2-oxo-2-[(2E)-2-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino]ethyl}benzenesulfonamide
   Show/Hide
C24H21ClN4O6S
 1
1
Ki = 596 nM
   TI
   LI
   LO
   TS
CP0854598
2-(N-(3-chlorophenyl)phenylsulfonamido)-N'-(1-(2-hydroxyphenyl)ethylidene)acetohydrazide
   Show/Hide
C22H20ClN3O4S
 1
1
Ki = 600 nM
   TI
   LI
   LO
   TS
CP0439005
2-[N-(benzenesulfonyl)-4-chloroanilino]-N-[(2-hydroxy-1H-indol-3-yl)imino]acetamide
   Show/Hide
C22H17ClN4O4S
 1
1
Ki = 611 nM
   TI
   LI
   LO
   TS
CP0250764
2-(4-chloro-N-[4-(3-hydroxypropyl)phenyl]sulfonylanilino)-N-[(2-hydroxy-1H-indol-3-yl)imino]acetamide
   Show/Hide
C25H23ClN4O5S
 1
1
Ki = 615 nM
   TI
   LI
   LO
   TS
CP0446409
2-(4-chloro-N-[4-[3-(dimethylamino)propoxy]phenyl]sulfonylanilino)-N-[(2-hydroxy-1H-pyrrolo[3,2-c]pyridin-3-yl)imino]acetamide
   Show/Hide
C26H27ClN6O5S
 1
1
Ki = 618 nM
   TI
   LI
   LO
   TS
CP0718296
N-(4-chlorophenyl)-4-ethoxy-N-(2-(2-(2-hydroxybenzylidene)hydrazinyl)-2-oxoethyl)benzenesulfonamide
   Show/Hide
C23H22ClN3O5S
 1
1
Ki = 650 nM
   TI
   LI
   LO
   TS
CP0485778
2-(4-chloro-N-[4-[3-(dimethylamino)propoxy]phenyl]sulfonylanilino)-N-[(1-hydroxy-3-oxo-2H-isoquinolin-4-yl)imino]acetamide
   Show/Hide
C28H28ClN5O6S
 1
1
Ki = 730 nM
   TI
   LI
   LO
   TS
CP0485597
2-[3-[[2-(4-chloro-N-[4-[3-(dimethylamino)propoxy]phenyl]sulfonylanilino)acetyl]diazenyl]-2-hydroxyindol-1-yl]acetamide
   Show/Hide
C29H31ClN6O6S
 1
1
Ki = 1103 nM
   TI
   LI
   LO
   TS
CP0176028
CHEMBL2113211
   Show/Hide
C25H23ClN4O6S
 1
1
Ki = 1180 nM
   TI
   LI
   LO
   TS
CP0453758
methyl 3-[[2-(4-chloro-N-[4-[3-(dimethylamino)propoxy]phenyl]sulfonylanilino)acetyl]diazenyl]-2-hydroxy-1H-indole-7-carboxylate
   Show/Hide
C29H30ClN5O7S
 1
1
Ki = 1286 nM
   TI
   LI
   LO
   TS
CP0480330
2-(4-chloro-N-(4-propoxyphenyl)sulfonylanilino)-N-[(2-hydroxy-1H-indol-3-yl)imino]acetamide
   Show/Hide
C25H23ClN4O5S
 1
1
Ki = 1390 nM
   TI
   LI
   LO
   TS
CP0070065
4-ethoxy-N-(2-oxo-2-(2-(2-oxoindolin-3-ylidene)hydrazinyl)ethyl)-N-p-tolylbenzenesulfonamide
   Show/Hide
C25H24N4O5S
 1
1
Ki = 1410 nM
   TI
   LI
   LO
   TS
CP0391575
2-(2-(2-(4-ethoxy-N-(4-methoxyphenyl)phenylsulfonamido)acetyl)-1,2,3,4-tetrahydroisoquinolin-3-yl)acetamide
   Show/Hide
C28H31N3O6S
 1
1
Ki = 1600 nM
   TI
   LI
   LO
   TS
CP0467145
2-(2-(4-ethoxy-N-(4-methoxyphenyl)phenylsulfonamido)acetyl)isoindoline-1-carboxamide
   Show/Hide
C26H27N3O6S
 1
1
Ki = 1600 nM
   TI
   LI
   LO
   TS
CP0391566
2-(2-(2-(4-ethoxy-N-p-tolylphenylsulfonamido)acetyl)-1,2,3,4-tetrahydroisoquinolin-3-yl)acetamide
   Show/Hide
C28H31N3O5S
 1
1
Ki = 1800 nM
   TI
   LI
   LO
   TS
CP0684505
N-(4-chlorophenyl)-4-ethoxy-N-(2-oxo-2-(2-(pyridin-2-ylmethylene)hydrazinyl)ethyl)benzenesulfonamide
   Show/Hide
C22H21ClN4O4S
 1
1
Ki = 1860 nM
   TI
   LI
   LO
   TS
CP0483731
2-(4-chloro-N-(4-propylphenyl)sulfonylanilino)-N-[(2-hydroxy-1H-indol-3-yl)imino]acetamide
   Show/Hide
C25H23ClN4O4S
 1
1
Ki = 2120 nM
   TI
   LI
   LO
   TS
CP0910343
4-ethoxy-N-{2-[2-(2-hydroxybenzylidene)hydrazino]-2-oxoethyl}-N-(4-methylphenyl)benzenesulfonamide
   Show/Hide
C24H25N3O5S
 1
1
Ki = 3215 nM
   TI
   LI
   LO
   TS
CP0321565
2-(4-chloro-N-(4-ethoxyphenyl)sulfonylanilino)-N-[(2-hydroxy-1H-pyrrolo[3,2-c]pyridin-3-yl)imino]acetamide
   Show/Hide
C23H20ClN5O5S
 1
1
Ki = 3610 nM
   TI
   LI
   LO
   TS
CP0515591
N-[(2-hydroxy-1H-indol-3-yl)imino]-2-(4-methyl-N-(4-propoxyphenyl)sulfonylanilino)acetamide
   Show/Hide
C26H26N4O5S
 1
1
Ki = 3730 nM
   TI
   LI
   LO
   TS
CP0198146
2-(N-(4-butoxyphenyl)sulfonyl-4-chloroanilino)-N-[(2-hydroxy-1H-indol-3-yl)imino]acetamide
   Show/Hide
C26H25ClN4O5S
 1
1
Ki = 3980 nM
   TI
   LI
   LO
   TS
CP0453756
2-(N-(4-tert-butylphenyl)sulfonyl-4-chloroanilino)-N-[(2-hydroxy-1H-indol-3-yl)imino]acetamide
   Show/Hide
C26H25ClN4O4S
 1
1
Ki = 4940 nM
   TI
   LI
   LO
   TS
CP0498457
CHEMBL2113205
   Show/Hide
C24H19N5O4S
 1
1
Ki = 6880 nM
   TI
   LI
   LO
   TS
CP0377964
2-(N-(4-ethoxyphenyl)sulfonyl-4-methylanilino)-3-hydroxy-N-[(2-hydroxy-1H-indol-3-yl)imino]propanamide
   Show/Hide
C26H26N4O6S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0391565
2-(4-chloro-N-[4-(2-methylbutan-2-yl)phenyl]sulfonylanilino)-N-[(2-hydroxy-1H-indol-3-yl)imino]acetamide
   Show/Hide
C27H27ClN4O4S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0393402
2-[N-(benzenesulfonyl)-4-ethoxyanilino]-N-(3-chloro-2-methylphenyl)acetamide
   Show/Hide
C23H23ClN2O4S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0441895
2-[N-(benzenesulfonyl)-4-methylanilino]-N-(3-chloro-2-methylphenyl)acetamide
   Show/Hide
C22H21ClN2O3S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0453759
N-[(2-hydroxy-1H-indol-3-yl)imino]-2-(4-methyl-N-naphthalen-1-ylsulfonylanilino)acetamide
   Show/Hide
C27H22N4O4S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0480327
2-(N-(4-ethoxyphenyl)sulfonyl-4-methylanilino)-N-[(2-hydroxy-1H-indol-3-yl)imino]propanamide
   Show/Hide
C26H26N4O5S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0480329
2-[N-(benzenesulfonyl)-4-chloroanilino]-N-(3-chloro-2-methylphenyl)acetamide
   Show/Hide
C21H18Cl2N2O3S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0847573
N-(4-methylphenyl)-N-{2-oxo-2-[2-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino]ethyl}-2-naphthalenesulfonamide
   Show/Hide
C27H22N4O4S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0847574
4-ethoxy-N-(2-{(2E)-2-[1-(1-hydroxy-2-naphthyl)ethylidene]hydrazino}-2-oxoethyl}-N-(4-methylphenyl)benzenesulfonamide
   Show/Hide
C29H29N3O5S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0853634
N-(2-{2-[4-(diethylamino)-2-hydroxybenzylidene]hydrazino}-2-oxoethyl)-4-ethoxy-N-(4-methylphenyl)benzenesulfonamide
   Show/Hide
C28H34N4O5S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0854609
N-{2-{(E)-[2-(2-{[(4-ethoxyphenyl)sulfonyl]-4-methylanilino}acetyl)hydrazono]methyl}phenyl)acetamide
   Show/Hide
C26H28N4O5S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0879679
N-{2-[(2E)-2-(2-aminobenzylidene)hydrazino]-2-oxoethyl}-4-ethoxy-N-(4-methylphenyl)benzenesulfonamide
   Show/Hide
C24H26N4O4S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0889528
3-({[4-chloro({4-[3-(dimethylamino)propoxy]phenyl}sulfonyl)anilino]acetyl}hydrazono)-2-oxo-2,3-dihydro-1H-indole-7-carboxylic acid
   Show/Hide
C28H28ClN5O7S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0889529
N-(4-chlorophenyl)-4-ethoxy-N-{2-[(2E)-2-(1H-imidazol-2-ylmethylene)hydrazino]-2-oxoethyl}benzenesulfonamide
   Show/Hide
C20H20ClN5O4S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0889532
4-ethoxy-N-(2-{2-[(2-hydroxy-1-naphthyl)methylene]hydrazino}-2-oxoethyl}-N-(4-methylphenyl)benzenesulfonamide
   Show/Hide
C29H29N3O5S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0889533
3-[({[(4-ethoxyphenyl)sulfonyl]-4-methylanilino}-acetyl)hydrazono]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid
   Show/Hide
C25H24N4O8S2
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0889534
4-ethoxy-N-(4-methylphenyl)-N-{3-oxo-3-[2-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino]propyl}benzenesulfonamide
   Show/Hide
C26H26N4O5S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0904928
4-ethoxy-N-{2-[2-(5-nitro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino]-2-oxoethyl}-N-phenylbenzenesulfonamide
   Show/Hide
C24H21N5O7S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0907489
N-(4-methylphenyl)-N-{2-oxo-2-[2-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino]ethyl}[1,1'-biphenyl]-4-sulfonamide
   Show/Hide
C29H24N4O4S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0910289
4-ethoxy-N-{2-[2-(5-iodo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino]-2-oxoethyl}-N-phenylbenzenesulfonamide
   Show/Hide
C24H21IN4O5S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0910329
4-ethoxy-N-{2-oxo-2-[2-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino]ethyl}-N-phenylbenzenesulfonamide
   Show/Hide
C24H22N4O5S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0911081
4'-methoxy-N-(4-methylphenyl)-N-{2-oxo-2-[2-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino]ethyl}[1,1'-biphenyl]-4-sulfonamide
   Show/Hide
C30H26N4O5S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0916890
N'-(1-(2-hydroxyphenyl)ethylidene)-2-(N-phenylphenylsulfonamido)acetohydrazide
   Show/Hide
C22H21N3O4S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0926723
N-(2-{2-[1-(2,4-dihydroxyphenyl)ethylidene]hydrazino}-2-oxoethyl)-4-ethoxy-N-(4-methylphenyl)benzenesulfonamide
   Show/Hide
C25H27N3O6S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS