General Information of the Compound
Compound ID
CP0321565
Compound Name
CHEMBL2113202
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Formula
C23H20ClN5O5S
Molecular Weight
513.963
Canonical SMILES
CCOc1ccc(cc1)S(=O)(=O)N(CC(=O)NN=C1C(=O)Nc2ccncc12)c1ccc(Cl)cc1
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InChI
InChI=1S/C23H20ClN5O5S/c1-2-34-17-7-9-18(10-8-17)35(32,33)29(16-5-3-15(24)4-6-16)14-21(30)27-28-22-19-13-25-12-11-20(19)26-23(22)31/h3-13H,2,14H2,1H3,(H,27,30)(H,26,28,31)
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InChIKey
DWBXKUWLRDJMQF-UHFFFAOYSA-N
Physicochemical Property
logP
2.8016
Rotatable Bonds
8
Heavy Atom Count
35
Polar Areas
130.06
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
7
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
SID: 16730685
ChEMBL ID
CHEMBL2113202
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01658, Oxytocin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000065 HEK293-EBNA Homo sapiens (Human)  1
1
Ki = 64 nM
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   LI
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   TS
Biochemical Assays
1 Ki = 64.57 nM
Protein ID: PT01839, Vasopressin V1a receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000065 HEK293-EBNA Homo sapiens (Human)  1
1
Ki = 3610 nM
   TI
   LI
   LO
   TS