Brief Information of the Cell Line and Protein
Cell Line ID: CL000063 , Hep-G2
 Cell Line Info 
Synonyms
HEP-G2
Hep G2
HEP G2
HepG2
HEPG2
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0027
Protein ID: PT00962 , Glycogen synthase kinase-3 beta
 Protein Info 
Gene Name GSK3B
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P49841
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000063
 Cell Line Info 
 Protein ID: PT00962
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0077343
 Compound Info 
6-amino-7-fluoro-12-methyl-4-oxo-8-[2-(pyridin-2-ylamino)ethylamino]spiro[10-oxa-1-azatricyclo[7.4.1.05,14]tetradeca-2,5,7,9(14)-tetraene-13,1'-cyclobutane]-3-carboxylic acid
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C24H26FN5O4
  1
1
EC50 = 1400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0023692
 Compound Info 
6-(2-(4-(2,4-dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-ylamino)ethylamino)nicotinonitrile
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C22H18Cl2N8
  1
1
EC50 = 1500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0126504
 Compound Info 
6-amino-7-fluoro-11-methyl-4-oxo-8-[2-(pyridin-2-ylamino)ethylamino]spiro[10-oxa-1-azatricyclo[7.4.1.05,14]tetradeca-2,5,7,9(14)-tetraene-13,1'-cyclobutane]-3-carboxylic acid
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C24H26FN5O4
  1
1
EC50 = 2100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0077341
 Compound Info 
6-amino-7-fluoro-4-oxo-8-[2-(pyridin-2-ylamino)ethylamino]spiro[10-oxa-1-azatricyclo[7.4.1.05,14]tetradeca-2,5,7,9(14)-tetraene-13,1'-cyclobutane]-3-carboxylic acid
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C23H24FN5O4
  1
1
EC50 = 3200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0253265
 Compound Info 
6-amino-7-fluoro-4-oxo-8-[2-(pyridin-2-ylamino)ethylamino]spiro[10-oxa-1-azatricyclo[7.4.1.05,14]tetradeca-2,5,7,9(14)-tetraene-13,1'-cyclopentane]-3-carboxylic acid
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C24H26FN5O4
  1
1
EC50 = 13000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0271728
 Compound Info 
8-amino-7-fluoro-10-oxo-6-[2-(pyridin-2-ylamino)ethylamino]spiro[4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-2,1'-cyclopentane]-11-carboxylic acid
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C23H24FN5O4
  1
1
EC50 = 20000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS