Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-amino-7-fluoro-12-methyl-4-oxo-8-[2-(pyridin-2-ylamino)ethylamino]spiro[10-oxa-1-azatricyclo[7.4.1.05,14]tetradeca-2,5,7,9(14)-tetraene-13,1'-cyclobutane]-3-carboxylic acid
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 PubChem ID
CID: 25253822
SID: 58087867
Canonical SMILES
CC1COc2c(NCCNc3ccccn3)c(F)c(N)c3c2n(cc(C(O)=O)c3=O)C11CCC1
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Compound Formula C24H26FN5O4
Compound Structure
Protein Name
 Protein Info 
Glycogen synthase kinase-3 beta
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase GSK family
Uniprot ID
P49841
Gene Name
GSK3B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 1400 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 10 nM