Brief Information of the Cell Line and Protein
Cell Line ID: CL000053 , COS-7
Synonyms
Cos-7
COS 7
Cos 7
COS7
Cos7
CV-1 in Origin Simian-7
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0224
Protein ID: PT06620 , Sodium/nucleoside cotransporter 2
Gene Name SLC28A2
Organism Rattus norvegicus, Rat
Protein Classification Transporter
Uniprot ID Q62773
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000053  Protein ID: PT06620
 
Compound ID Compound Name Compound Formula
CP0420092
(2R,3R,4S,5R)-2-[2-[[3-(4-hydroxybutoxy)-4-phenylphenyl]methylamino]benzimidazol-1-yl]-5-(hydroxymethyl)oxolane-3,4-diol
   Show/Hide
C29H33N3O6
 1
1
IC50 = 1500 nM
   TI
   LI
   LO
   TS
CP0464430
(2R,3R,4S,5R)-2-[6-amino-8-[[3-(4-hydroxybutoxy)-4-phenylphenyl]methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
   Show/Hide
C27H32N6O6
 1
1
IC50 = 38000 nM
   TI
   LI
   LO
   TS
CP0420048
(2R,3R,4S,5R)-2-[6-amino-8-[[3-(3-hydroxypropoxy)-4-phenylphenyl]methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
   Show/Hide
C26H30N6O6
 1
1
IC50 = 45100 nM
   TI
   LI
   LO
   TS
CP0420093
(2R,3R,4S,5R)-2-[6-amino-8-[[3-(5-hydroxypentoxy)-4-phenylphenyl]methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
   Show/Hide
C28H34N6O6
 1
1
IC50 = 60000 nM
   TI
   LI
   LO
   TS
CP0420026
(2R,3R,4S,5R)-2-[6-amino-8-[(4-pyridin-3-ylphenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
   Show/Hide
C22H23N7O4
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0420088
2-[5-[[[6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-8-yl]amino]methyl]-2-phenylphenoxy]acetamide
   Show/Hide
C25H27N7O6
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0420153
(2R,3R,4S,5R)-2-[6-amino-8-[[3-(2-hydroxyethoxy)-4-phenylphenyl]methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
   Show/Hide
C25H28N6O6
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS