Brief Information of the Cell Line and Protein
Cell Line ID: CL000053 , COS-7
 Cell Line Info 
Synonyms
Cos-7
COS 7
Cos 7
COS7
Cos7
CV-1 in Origin Simian-7
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0224
Protein ID: PT06288 , Vitamin D3 receptor
 Protein Info 
Gene Name VDR
Organism Mus musculus, Mouse
Protein Classification Transcription factor
Uniprot ID P48281
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000053
 Cell Line Info 
 Protein ID: PT06288
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0867864
 Compound Info 
(20R)-1-alpha-25-dihydroxy-2-beta-(2-hydroxyethoxy)-16-ene-22-thia-26,27-dimethyl-19,24-dinorvitamin D3
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C28H46O5S
  1
1
EC50 = 0.024 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0900889
 Compound Info 
(20S)-(2E)-1-alpha-25-Dihydroxy-2-[2-(hydroxy)-ethylidene]-16-ene-22-thia-26,27-dimethyl-19,24-dinorvitamin D3
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C28H44O4S
  1
1
EC50 = 0.026 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0858884
 Compound Info 
(20R)-(2E)-1-alpha-25-Dihydroxy-2-[2-(hydroxy)-ethylidene]-16-ene-22-thia-26,27-dimethyl-19,24-dinorvitamin D3
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C28H44O4S
  1
1
EC50 = 0.029 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0888468
 Compound Info 
(20S)-1-alpha-25-dihydroxy-2-beta-(2-hydroxyethoxy)-16-ene-22-thia-26,27-dimethyl-19-norvitamin D3
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C30H50O4S
  1
1
EC50 = 0.03 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0888467
 Compound Info 
(20S)-1-alpha-25-dihydroxy-2-beta-(2-hydroxyethoxy)-16-ene-22-thia-24-homo-26,27-dimethyl-19-norvitamin D3
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C31H52O4S
  1
1
EC50 = 0.09 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0850262
 Compound Info 
(20S)-1-alpha-2-alpha-25-Trihydroxy-2beta-methyl-16-ene-22-thia-26,27-dimethyl-19,24-dinorvitamin D3
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C27H44O4S
  1
1
EC50 = 1.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0898960
 Compound Info 
(20R)-1-alpha-2-alpha-25-Trihydroxy-2-beta-methyl-16-ene-22-thia-26,27-dimethyl-19,24-dinorvitamin D3
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C27H44O4S
  1
1
EC50 = 4.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS