Brief Information of the Cell Line and Protein
Cell Line ID: CL000053 , COS-7
Synonyms
Cos-7
COS 7
Cos 7
COS7
Cos7
CV-1 in Origin Simian-7
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0224
Protein ID: PT05799 , Galanin receptor type 2
Gene Name GALR2
Organism Rattus norvegicus, Rat
Protein Classification Membrane receptor
Uniprot ID O08726
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000053  Protein ID: PT05799
 
Compound ID Compound Name Compound Formula
CP0399290
(2S)-2-amino-3-((2-(benzyloxy)phenyl)(3-fluorophenyl)methoxy)propanoic acid
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C23H22FNO4
 1
1
IC50 = 21.1 nM
   TI
   LI
   LO
   TS
CP0476239
(3S,6S,9S,15aR)-9-sec-butyl-6-((1-methoxy-1H-indol-3-yl)methyl)-3-(5-oxohexyl)octahydro-1H-pyrido[1,2-a][1,4,7,10]tetraazacyclododecine-1,4,7,10(12H,13H,14H)-tetraone
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C32H45N5O6
 1
1
IC50 = 87.7 nM
   TI
   LI
   LO
   TS
CP0497907
(3S,6S,9S,12S)-3-benzyl-6,9,12-tri-sec-butyl-1,4,7,10-tetraazacyclododecane-2,5,8,11-tetraone
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C27H42N4O4
 1
1
IC50 = 226 nM
   TI
   LI
   LO
   TS
CP0441398
(3S,6S,9S,12S)-3-benzyl-9,12-di-sec-butyl-6-((2S,3R)-3-hydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-2,5,8,11-tetraone
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C27H42N4O5
 1
1
IC50 = 278 nM
   TI
   LI
   LO
   TS
CP0474576
(3S,6S,9S,12S)-3-benzyl-9-sec-butyl-6-((2S,3R)-3-hydroxybutan-2-yl)-12-isopropyl-1,4,7,10-tetraazacyclododecane-2,5,8,11-tetraone
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C26H40N4O5
 1
1
IC50 = 450 nM
   TI
   LI
   LO
   TS
CP0476238
(3S,6S,9S,12S)-3-benzyl-6-((2S,3R)-3-hydroxybutan-2-yl)-9,12-diisopropyl-1,4,7,10-tetraazacyclododecane-2,5,8,11-tetraone
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C25H38N4O5
 1
1
IC50 = 542 nM
   TI
   LI
   LO
   TS
CP0437601
(3S,6S,9S,12S)-3-benzyl-12-sec-butyl-6-((2S,3R)-3-hydroxybutan-2-yl)-9-isopropyl-1,4,7,10-tetraazacyclododecane-2,5,8,11-tetraone
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C26H40N4O5
 1
1
IC50 = 574 nM
   TI
   LI
   LO
   TS
CP0456132
(S)-2-((2S,5S,8S,11S)-5-benzyl-8,11-di-sec-butyl-3,6,9,12-tetraoxo-1,4,7,10-tetraazacyclododecan-2-yl)-3-oxobutane-1-sulfonic acid
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C27H40N4O8S
 1
1
IC50 = 2260 nM
   TI
   LI
   LO
   TS