Brief Information of the Cell Line and Protein
Cell Line ID: CL000053 , COS-7
Synonyms
Cos-7
COS 7
Cos 7
COS7
Cos7
CV-1 in Origin Simian-7
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0224
Protein ID: PT05659 , Very long chain fatty acid elongase 3
Gene Name ELOVL3
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID Q9HB03
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000053  Protein ID: PT05659
 
Compound ID Compound Name Compound Formula
CP0504385
3-[2-(4-isopropylphenyl)-5-methyl-3-oxo-2,3-dihydro-1H-pyrazol-4-yl]-6,6-dimethyl-1-phenyl-3-(trifluoromethyl)-3,5,6,7-tetrahydro-1H-indole-2,4-dione
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C30H30F3N3O3
 1
1
IC50 = 59 nM
   TI
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CP0480497
3-[2-(4-chlorophenyl)-5-methyl-3-oxo-2,3-dihydro-1H-pyrazol-4-yl]-6,6-dimethyl-1-phenyl-3-(trifluoromethyl)-3,5,6,7-tetrahydro-1H-indole-2,4-dione
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C27H23ClF3N3O3
 1
1
IC50 = 221 nM
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CP0428615
6,6-dimethyl-3-{5-methyl-3-oxo-2-[4-(trifluoromethoxy)phenyl]-2,3-dihydro-1H-pyrazol-4-yl}-1-phenyl-3-(trifluoromethyl)-3,5,6,7-tetrahydro-1H-indole-2,4-dione
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C28H23F6N3O4
 1
1
IC50 = 337 nM
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CP0495958
3-[2-(4-methyllphenyl)-5-methyl-3-oxo-2,3-dihydro-1H-pyrazol-4-yl]-6,6-dimethyl-1-phenyl-3-(trifluoromethyl)-3,5,6,7-tetrahydro-1H-indole-2,4-dione
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C28H26F3N3O3
 1
1
IC50 = 375 nM
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CP0485234
3-[2-(4-methoxyphenyl)-5-methyl-3-oxo-2,3-dihydro-1H-pyrazol-4-yl]-6,6-dimethyl-1-phenyl-3-(trifluoromethyl)-3,5,6,7-tetrahydro-1H-indole-2,4-dione
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C28H26F3N3O4
 1
1
IC50 = 503 nM
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CP0515764
3-[2-(4-cyanophenyl)-5-methyl-3-oxo-2,3-dihydro-1H-pyrazol-4-yl]-6,6-dimethyl-1-phenyl-3-(trifluoromethyl)-3,5,6,7-tetrahydro-1H-indole-2,4-dione
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C28H23F3N4O3
 1
1
IC50 = 1100 nM
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CP0857816
2-[(1-Methyl-1H-imidazol-4-yl)sulfonyl]-N-[4-(propan-2-yloxy)phenyl]-2-azabicyclo[2.2.2]octane-6-carboxamide
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C21H28N4O4S
 1
1
IC50 = 1510 nM
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CP0443407
6,6-dimethyl-3-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1-phenyl-3-(trifluoromethyl)-3,5,6,7-tetrahydro-1H-indole-2,4-dione
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C27H24F3N3O3
 1
1
IC50 > 10 nM
   TI
   LI
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   TS