Brief Information of the Cell Line and Protein
Cell Line ID: CL000053 , COS-7
Synonyms
Cos-7
COS 7
Cos 7
COS7
Cos7
CV-1 in Origin Simian-7
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0224
Protein ID: PT05434 , P2Y purinoceptor 14
Gene Name P2RY14
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID Q15391
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000053  Protein ID: PT05434
 
Compound ID Compound Name Compound Formula
CP0469840
[[(2R,3S,4R,5R)-3,4-dihydroxy-5-(4-oxo-2-sulfanylidenepyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] hydrogen phosphate
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C15H24N2O16P2S
 1
1
EC50 = 49 nM
   TI
   LI
   LO
   TS
CP0452617
[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5S)-3,4,5-trihydroxyoxolan-2-yl]methyl hydrogen phosphate
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C14H22N2O16P2
 1
1
EC50 = 238 nM
   TI
   LI
   LO
   TS
CP0385875
UDP-alpha-D-glucose
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C15H24N2O17P2
 2
1
EC50 = 261 nM
   TI
   LI
   LO
   TS
2
EC50 = 350 nM
   TI
   LI
   LO
   TS
CP0401576
[[(2R,3S,4R,5R)-3,4-dihydroxy-5-(2-oxo-4-sulfanylidenepyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] hydrogen phosphate
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C15H24N2O16P2S
 2
1
EC50 = 290 nM
   TI
   LI
   LO
   TS
2
EC50 = 350 nM
   TI
   LI
   LO
   TS
CP0504583
[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4S,5R)-3,4,5-trihydroxy-5-(hydroxymethyl)oxolan-2-yl]methyl hydrogen phosphate
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C15H24N2O17P2
 1
1
EC50 = 323 nM
   TI
   LI
   LO
   TS
CP0421299
(2S,3S,4S,5R,6R)-6-[[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
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C15H22N2O18P2
 1
1
EC50 = 370 nM
   TI
   LI
   LO
   TS
CP0463374
[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4S,5R,6S)-3,4,5,6-tetrahydroxyoxan-2-yl]methyl hydrogen phosphate
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C15H24N2O17P2
 1
1
EC50 = 373 nM
   TI
   LI
   LO
   TS
CP0541808
(2S,3S,4S,5R,6R)-6-[[[(2R,3S,4R,5R)-3,4-dihydroxy-5-(4-oxo-2-sulfanylidenepyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
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C15H22N2O17P2S
 1
1
EC50 = 420 nM
   TI
   LI
   LO
   TS
CP0477667
[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4S,5S)-3,4,5-trihydroxyoxolan-2-yl]methyl hydrogen phosphate
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C14H22N2O16P2
 1
1
EC50 = 460 nM
   TI
   LI
   LO
   TS
CP0401575
[(2R,3R,4S,5S,6S)-6-(2-acetamidoethylcarbamoyl)-3,4,5-trihydroxyoxan-2-yl] [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] hydrogen phosphate
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C19H30N4O18P2
 1
1
EC50 = 496 nM
   TI
   LI
   LO
   TS
CP0470265
[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl] hydrogen phosphate
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C15H24N2O16P2
 1
1
EC50 = 562 nM
   TI
   LI
   LO
   TS
CP0470264
[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] hydrogen phosphate
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C15H24N2O17P2
 1
1
EC50 = 588 nM
   TI
   LI
   LO
   TS
CP0470266
[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4S,5S,6S)-3,4,5,6-tetrahydroxyoxan-2-yl]methyl hydrogen phosphate
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C15H24N2O17P2
 1
1
EC50 = 658 nM
   TI
   LI
   LO
   TS
CP0278982
[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] hydrogen phosphate
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C15H24N2O17P2
 1
1
EC50 = 670 nM
   TI
   LI
   LO
   TS
CP0499300
[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4S,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)oxolan-2-yl]methyl hydrogen phosphate
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C15H24N2O17P2
 1
1
EC50 = 880 nM
   TI
   LI
   LO
   TS
CP0383614
[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] hydrogen phosphate
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C15H24N2O17P2
 1
1
EC50 = 910 nM
   TI
   LI
   LO
   TS
CP0390310
tert-butyl N-[2-[[(2S,3S,4S,5R,6R)-6-[[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-3,4,5-trihydroxyoxane-2-carbonyl]amino]ethyl]carbamate
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C22H36N4O19P2
 1
1
EC50 = 951 nM
   TI
   LI
   LO
   TS
CP0554705
[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2S,3R,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl] hydrogen phosphate
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C15H24N2O17P2
 1
1
EC50 = 1880 nM
   TI
   LI
   LO
   TS
CP0429834
[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,5R,6R)-2,3,4,5,6-pentahydroxycyclohexyl] hydrogen phosphate
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C15H24N2O17P2
 1
1
EC50 = 1880 nM
   TI
   LI
   LO
   TS
CP0499299
[(2R,3R,4S,5S,6S)-6-(2-aminoethylcarbamoyl)-3,4,5-trihydroxyoxan-2-yl] [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] hydrogen phosphate
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C17H28N4O17P2
 1
1
EC50 = 2590 nM
   TI
   LI
   LO
   TS
CP0427215
[[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-methylsulfanyl-2-oxo-1,6-dihydropyrimidin-3-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] hydrogen phosphate
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C16H28N2O16P2S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0032210
4-(4-piperidin-4-ylphenyl)-7-[4-(trifluoromethyl)phenyl]naphthalene-2-carboxylic acid
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C29H24F3NO2
 1
1
IC50 = 0.4 nM
   TI
   LI
   LO
   TS