Brief Information of the Cell Line and Protein
Cell Line ID: CL000053 , COS-7
Synonyms
Cos-7
COS 7
Cos 7
COS7
Cos7
CV-1 in Origin Simian-7
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0224
Protein ID: PT04640 , Patatin-like phospholipase domain-containing protein 2
Gene Name PNPLA2
Organism Mus musculus, Mouse
Protein Classification Enzyme
Uniprot ID Q8BJ56
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000053  Protein ID: PT04640
 
Compound ID Compound Name Compound Formula
CP0565095
ethyl N-[3-[4-(dimethylamino)phenyl]phenyl]carbamate
   Show/Hide
C17H20N2O2
 1
1
IC50 = 3000 nM
   TI
   LI
   LO
   TS
CP0422918
methyl N-[3-[4-(dimethylamino)phenyl]phenyl]carbamate
   Show/Hide
C16H18N2O2
 1
1
IC50 = 5000 nM
   TI
   LI
   LO
   TS
CP0187270
4-[(E)-(4-phenylpiperazin-1-yl)iminomethyl]benzene-1,3-diol
   Show/Hide
C17H19N3O2
 1
1
IC50 = 10000 nM
   TI
   LI
   LO
   TS
CP0563809
2-methylpropyl N-[3-[4-(dimethylamino)phenyl]phenyl]carbamate
   Show/Hide
C19H24N2O2
 1
1
IC50 = 22000 nM
   TI
   LI
   LO
   TS
CP0479417
4-[(E)-(4-phenylpiperidin-1-yl)iminomethyl]benzene-1,3-diol
   Show/Hide
C18H20N2O2
 1
1
IC50 = 40000 nM
   TI
   LI
   LO
   TS
CP0565800
ethyl 3-[4-(dimethylamino)phenyl]benzoate
   Show/Hide
C17H19NO2
 1
1
IC50 = 40000 nM
   TI
   LI
   LO
   TS
CP0397785
4-[(E)-(4-phenylpiperazin-1-yl)iminomethyl]benzonitrile
   Show/Hide
C18H18N4
 1
1
IC50 = 50000 nM
   TI
   LI
   LO
   TS
CP0414601
4-[(E)-(4-phenylpiperazin-1-yl)iminomethyl]phenol
   Show/Hide
C17H19N3O
 1
1
IC50 = 50000 nM
   TI
   LI
   LO
   TS
CP0453687
4-[(E)-[4-(4-fluorophenyl)piperazin-1-yl]iminomethyl]benzene-1,3-diol
   Show/Hide
C17H18FN3O2
 1
1
IC50 = 50000 nM
   TI
   LI
   LO
   TS
CP0565091
ethyl 5-(4-ethoxyphenyl)furan-2-carboxylate
   Show/Hide
C15H16O4
 1
1
IC50 = 50000 nM
   TI
   LI
   LO
   TS
CP0565096
ethyl 3-(4-ethoxyphenyl)benzoate
   Show/Hide
C17H18O3
 1
1
IC50 = 50000 nM
   TI
   LI
   LO
   TS
CP0409963
2-methoxy-4-[(E)-(4-phenylpiperazin-1-yl)iminomethyl]phenol
   Show/Hide
C18H21N3O2
 1
1
IC50 = 60000 nM
   TI
   LI
   LO
   TS
CP0513793
ethyl 6-(4-ethoxyphenyl)pyridine-2-carboxylate
   Show/Hide
C16H17NO3
 1
1
IC50 = 60000 nM
   TI
   LI
   LO
   TS
CP0546121
ethyl 3-(1H-indol-5-yl)benzoate
   Show/Hide
C17H15NO2
 1
1
IC50 = 60000 nM
   TI
   LI
   LO
   TS
CP0449855
3-[(E)-(4-phenylpiperazin-1-yl)iminomethyl]phenol
   Show/Hide
C17H19N3O
 1
1
IC50 = 70000 nM
   TI
   LI
   LO
   TS
CP0513796
1-ethoxy-4-(3-methylphenyl)benzene
   Show/Hide
C15H16O
 1
1
IC50 = 70000 nM
   TI
   LI
   LO
   TS
CP0555462
3-[3-(4-ethoxyphenyl)phenyl]-1,1-dimethylurea
   Show/Hide
C17H20N2O2
 1
1
IC50 = 70000 nM
   TI
   LI
   LO
   TS
CP0560769
2-methoxyethyl 3-(4-ethoxyphenyl)benzoate
   Show/Hide
C18H20O4
 1
1
IC50 = 70000 nM
   TI
   LI
   LO
   TS
CP0563517
1-[3-[4-(dimethylamino)phenyl]phenyl]-1,3,3-trimethylurea
   Show/Hide
C18H23N3O
 1
1
IC50 = 70000 nM
   TI
   LI
   LO
   TS
CP0563518
ethyl 5-(4-ethoxyphenyl)thiophene-2-carboxylate
   Show/Hide
C15H16O3S
 1
1
IC50 = 70000 nM
   TI
   LI
   LO
   TS
CP0531295
phenyl N-[3-[4-(dimethylamino)phenyl]phenyl]carbamate
   Show/Hide
C21H20N2O2
 1
1
IC50 = 73000 nM
   TI
   LI
   LO
   TS
CP0409942
2-[(E)-(4-phenylpiperazin-1-yl)iminomethyl]phenol
   Show/Hide
C17H19N3O
 1
1
IC50 = 75000 nM
   TI
   LI
   LO
   TS
CP0499155
(E)-1-(3,4-difluorophenyl)-N-(4-phenylpiperazin-1-yl)methanimine
   Show/Hide
C17H17F2N3
 1
1
IC50 = 75000 nM
   TI
   LI
   LO
   TS
CP0513794
ethyl 3-thiophen-3-ylbenzoate
   Show/Hide
C13H12O2S
 1
1
IC50 = 75000 nM
   TI
   LI
   LO
   TS
CP0513795
ethyl 3-(1-methylindol-5-yl)benzoate
   Show/Hide
C18H17NO2
 1
1
IC50 = 75000 nM
   TI
   LI
   LO
   TS
CP0557941
ethyl 3-[4-(piperidin-1-ylmethyl)phenyl]benzoate
   Show/Hide
C21H25NO2
 1
1
IC50 = 75000 nM
   TI
   LI
   LO
   TS
CP0409966
2-methoxy-5-[(E)-(4-phenylpiperazin-1-yl)iminomethyl]phenol
   Show/Hide
C18H21N3O2
 1
1
IC50 = 80000 nM
   TI
   LI
   LO
   TS
CP0531296
ethyl 2-(4-ethoxyphenyl)pyridine-4-carboxylate
   Show/Hide
C16H17NO3
 1
1
IC50 = 80000 nM
   TI
   LI
   LO
   TS
CP0565092
ethyl 3-(4-methoxyphenyl)benzoate
   Show/Hide
C16H16O3
 1
1
IC50 = 80000 nM
   TI
   LI
   LO
   TS
CP0560772
propan-2-yl N-[3-[4-(dimethylamino)phenyl]phenyl]carbamate
   Show/Hide
C18H22N2O2
 1
1
IC50 = 82000 nM
   TI
   LI
   LO
   TS
CP0555534
ethyl 3-[4-[1-(4-methylpiperazin-1-yl)ethyl]phenyl]benzoate
   Show/Hide
C22H28N2O2
 1
1
IC50 = 90000 nM
   TI
   LI
   LO
   TS
CP0557940
ethyl 3-thiophen-2-ylbenzoate
   Show/Hide
C13H12O2S
 1
1
IC50 = 90000 nM
   TI
   LI
   LO
   TS
CP0565094
3-(4-ethoxyphenyl)-N-ethylbenzamide
   Show/Hide
C17H19NO2
 1
1
IC50 = 90000 nM
   TI
   LI
   LO
   TS
CP0531297
ethyl 3-(4-nitrophenyl)benzoate
   Show/Hide
C15H13NO4
 1
1
IC50 = 95000 nM
   TI
   LI
   LO
   TS
CP0448211
(E)-1-(3,4-dimethoxyphenyl)-N-(4-phenylpiperazin-1-yl)methanimine
   Show/Hide
C19H23N3O2
 1
1
IC50 = 100000 nM
   TI
   LI
   LO
   TS
CP0422917
3-(4-ethoxyphenyl)aniline
   Show/Hide
C14H15NO
 1
1
IC50 = 100000 nM
   TI
   LI
   LO
   TS
CP0549405
butyl 3-(4-ethoxyphenyl)benzoate
   Show/Hide
C19H22O3
 1
1
IC50 = 100000 nM
   TI
   LI
   LO
   TS
CP0555460
ethyl 3-(4-hydroxyphenyl)benzoate
   Show/Hide
C15H14O3
 1
1
IC50 = 100000 nM
   TI
   LI
   LO
   TS
CP0555461
ethyl 3-[4-[(4-methylsulfonylpiperazin-1-yl)methyl]phenyl]benzoate
   Show/Hide
C21H26N2O4S
 1
1
IC50 = 100000 nM
   TI
   LI
   LO
   TS
CP0557942
ethyl 3-[5-[(4-methylsulfonylpiperazin-1-yl)methyl]furan-2-yl]benzoate
   Show/Hide
C19H24N2O5S
 1
1
IC50 = 100000 nM
   TI
   LI
   LO
   TS
CP0563516
3-[4-(dimethylamino)phenyl]aniline
   Show/Hide
C14H16N2
 1
1
IC50 = 100000 nM
   TI
   LI
   LO
   TS
CP0422920
3-[3-[4-(dimethylamino)phenyl]phenyl]-1,1-dimethylurea
   Show/Hide
C17H21N3O
 1
1
IC50 < 5000 nM
   TI
   LI
   LO
   TS