| Compound ID |
Compound Name |
Compound Formula |
|
CP0323320
|
2-(6-phenyl-1,3-benzothiazole-2-carbonyl)-5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole
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|
C17H13N5O4S2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0468663
|
US9169240, 27
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|
C18H15N5O4S2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0058220
|
(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl (2S)-2-formamido-4-methylpentanoate
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|
C29H53NO5
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0412063
|
5-fluoro-2-[5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole-2-carbonyl]-N-(2,2,2-trifluoroethyl)-1,3-benzothiazole-6-carboxamide
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|
C14H10F4N6O5S2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0517674
|
4-[6-fluoro-2-[5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole-2-carbonyl]-1,3-benzothiazol-5-yl]-N-(2,2,2-trifluoroethyl)benzamide
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|
C20H14F4N6O5S2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0419298
|
US9169240, 30
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|
C19H16N6O6S2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0061225
|
2-benzylsulfonyl-N-[2-(cyclopropylamino)-2-oxoethyl]-2-[6-(6-fluoropyridin-3-yl)-1,3-benzothiazol-2-yl]acetamide
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|
C26H23FN4O4S2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0401877
|
2-[5-fluoro-6-(6-fluoropyridin-3-yl)-1,3-benzothiazole-2-carbonyl]-5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole
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|
C16H10F2N6O4S2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0419297
|
US9169240, 29
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|
C17H12FN5O4S2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0482818
|
[5-[(methylsulfamoylamino)methyl]-1,3,4-oxadiazol-2-yl]-(6-phenyl-1,3-benzothiazol-2-yl)methanone
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|
C18H15N5O4S2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0384150
|
2-[2-methoxyethylsulfonyl-(6-phenyl-1,3-benzothiazol-2-yl)methyl]-5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole
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|
C20H21N5O6S3
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0384151
|
2-[(6-phenyl-1,3-benzothiazol-2-yl)-propan-2-ylsulfonylmethyl]-5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole
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|
C20H21N5O5S3
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0384153
|
2-[benzylsulfonyl-[6-(3-chlorophenyl)-1,3-benzothiazol-2-yl]methyl]-5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole
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|
C24H20ClN5O5S3
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0384200
|
2-[benzylsulfonyl-[6-(3,4-dichlorophenyl)-1,3-benzothiazol-2-yl]methyl]-5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole
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|
C24H19Cl2N5O5S3
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0421688
|
2-[(6-phenyl-1,3-benzothiazol-2-yl)-(3,3,3-trifluoropropylsulfonyl)methyl]-5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole
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|
C20H18F3N5O5S3
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0482586
|
5-[[5-[methylsulfonyl-(6-phenyl-1,3-benzothiazol-2-yl)methyl]-1,3,4-oxadiazol-2-yl]methyl]-1,3-thiazolidine-2,4-dione
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|
C21H16N4O5S3
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0323368
|
2-methylsulfonyl-2-(6-phenyl-1,3-benzothiazol-2-yl)-N-(2-sulfamoylethyl)acetamide
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|
C18H19N3O5S3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0410982
|
N-[3-(3,4-dichlorophenyl)propyl]-3-hydroxy-1-methyl-2-oxopyridine-4-carboxamide
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|
C16H16Cl2N2O3
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0412064
|
2-[5-fluoro-6-(1-oxo-2,3-dihydroisoindol-5-yl)-1,3-benzothiazole-2-carbonyl]-5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole
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|
C19H13FN6O5S2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0412065
|
2-[6-fluoro-5-(1-oxo-2,3-dihydroisoindol-5-yl)-1,3-benzothiazole-2-carbonyl]-5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole
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|
C19H13FN6O5S2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0450725
|
2-[6-(6-fluoropyridin-3-yl)-1,3-benzothiazole-2-carbonyl]-5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole
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|
C16H11FN6O4S2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0384152
|
2-[benzylsulfonyl-(6-phenyl-1,3-benzothiazol-2-yl)methyl]-5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole
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|
C24H21N5O5S3
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0429274
|
US9169240, 26
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|
C18H15N5O4S2
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0468661
|
2-[6-(3-oxo-1,2-dihydroisoindol-5-yl)-1,3-benzothiazole-2-carbonyl]-5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole
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|
C19H14N6O5S2
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0519336
|
4-[2-fluoro-4-[5-fluoro-2-[5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole-2-carbonyl]-1,3-benzothiazol-6-yl]benzoyl]morpholine
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|
C22H18F2N6O6S2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0573101
|
N-[(cyclopropyl- carbamoyl) methyl]-2- methanesulfonyl- 2-(6-phenyl-1,3- benzothiazol- 2-yl)acetamide
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|
C21H21N3O4S2
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0323367
|
2-methylsulfonyl-2-(6-phenyl-1,3-benzothiazol-2-yl)-N-(3-sulfamoylpropyl)acetamide
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|
C19H21N3O5S3
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0384154
|
2-[methylsulfonyl-(6-phenyl-1,3-benzothiazol-2-yl)methyl]-5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole
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|
C18H17N5O5S3
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
|
CP0421750
|
5-methyl-5-[[5-[methylsulfonyl-(6-phenyl-1,3-benzothiazol-2-yl)methyl]-1,3,4-oxadiazol-2-yl]methyl]imidazolidine-2,4-dione
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|
C22H19N5O5S2
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
|
CP0429256
|
US9169240, 25
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|
C18H15N5O4S2
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0480000
|
N-[3-(3,4-dichlorophenyl)propyl]-4-hydroxy-1-methyl-5-oxo-2H-pyrrole-3-carboxamide
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|
C15H16Cl2N2O3
|
1
|
| 1 |
IC50 = 76 nM
|
|
|
|
CP0126235
|
N-[(cyclopropyl- carbamoyl) methyl]-2-[6-(6- fluoropyridin-3- yl)-1,3- benzothiazol- 2-yl]-2-(3,3,3- trifluoropropane- sulfonyl)acetamide
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|
C22H20F4N4O4S2
|
1
|
| 1 |
IC50 = 79 nM
|
|
|
|
CP0224798
|
2-methylsulfonyl-2-(6-phenyl-1,3-benzothiazol-2-yl)-N-[2-(sulfamoylamino)ethyl]acetamide
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|
C18H20N4O5S3
|
1
|
| 1 |
IC50 = 81 nM
|
|
|
|
CP0455147
|
methyl N-[4-[2-[benzylsulfonyl-[5-[(sulfamoylamino)methyl]-1,3,4-oxadiazol-2-yl]methyl]-1,3-benzothiazol-6-yl]phenyl]carbamate
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|
C26H24N6O7S3
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0455148
|
4-[4-[2-[benzylsulfonyl-[5-[(sulfamoylamino)methyl]-1,3,4-oxadiazol-2-yl]methyl]-1,3-benzothiazol-6-yl]-2-chlorobenzoyl]morpholine
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|
C29H27ClN6O7S3
|
1
|
| 1 |
IC50 = 121 nM
|
|
|
|
CP0259244
|
N-[(cyclopropyl- carbamoyl) methyl]-2-[6-(6- fluoropyridin-3- yl)-1,3- benzothiazol- 2-yl]-2- methanesulfonyl- acetamide
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|
C20H19FN4O4S2
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0126236
|
N-[2-(cyclopropylamino)-2-oxoethyl]-2-[6-(6-fluoropyridin-3-yl)-1,3-benzothiazol-2-yl]-2-(2-methoxyethylsulfonyl)acetamide
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|
C22H23FN4O5S2
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0120856
|
US8987314, B101
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|
C23H26N4O7S3
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0066473
|
US8987314, B34
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|
C21H28N6O6S3
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0421749
|
4-[2-[benzylsulfonyl-[5-[(sulfamoylamino)methyl]-1,3,4-oxadiazol-2-yl]methyl]-1,3-benzothiazol-6-yl]-2-chloro-N,N-dimethylbenzamide
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|
C27H25ClN6O6S3
|
1
|
| 1 |
IC50 = 391 nM
|
|
|
|
CP0384139
|
5-[[5-[methylsulfonyl-[6-[4-(morpholine-4-carbonyl)phenyl]-1,3-benzothiazol-2-yl]methyl]-1,3,4-oxadiazol-2-yl]methyl]-1,3-thiazolidine-2,4-dione
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|
C26H23N5O7S3
|
1
|
| 1 |
IC50 = 450 nM
|
|
|
|
CP0127616
|
US8987314, B3
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|
C17H17FN4O5S3
|
1
|
| 1 |
IC50 = 4400 nM
|
|
|
|
CP0519335
|
US9169240, 49
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|
C18H13N5O3S
|
1
|
| 1 |
IC50 > 10 nM
|
|
|
