Brief Information of the Cell Line and Protein
Cell Line ID: CL000053 , COS-7
Synonyms
Cos-7
COS 7
Cos 7
COS7
Cos7
CV-1 in Origin Simian-7
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0224
Protein ID: PT02225 , Tyrosine-protein phosphatase non-receptor type 1
Gene Name PTPN1
Organism Mus musculus, Mouse
Protein Classification Enzyme
Uniprot ID P35821
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000053  Protein ID: PT02225
 
Compound ID Compound Name Compound Formula
CP0254995
5-{3-[(1E)-3-[3-hydroxy-2-(methoxycarbonyl)phenoxy]prop-1-en-1-yl]phenyl}-4-(hydroxymethyl)-1,2-oxazole-3-carboxylic acid
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C22H19NO8
 1
1
Ki = 920 nM
   TI
   LI
   LO
   TS
CP0151260
4-amino-5-{3-[(1E)-3-[3-hydroxy-2-(methoxycarbonyl)phenoxy]prop-1-en-1-yl]phenyl}-1,2-oxazole-3-carboxylic acid
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C21H18N2O7
 1
1
Ki = 2100 nM
   TI
   LI
   LO
   TS
CP0036444
5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-(methoxycarbonyl)phenoxy]prop-1-en-1-yl]phenyl}-1,2-oxazole-3-carboxylic acid
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C21H16FNO7
 1
1
Ki = 6900 nM
   TI
   LI
   LO
   TS
CP0036443
12-[(1E)-3-[3-hydroxy-2-(methoxycarbonyl)phenoxy]prop-1-en-1-yl]-3-oxa-4-azatricyclo[7.4.0.0^{2,6}]trideca-1(9),2(6),4,10,12-pentaene-5-carboxylic acid
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C23H19NO7
 1
1
Ki = 11500 nM
   TI
   LI
   LO
   TS
CP0883934
5-{3-[3-(3-Hydroxy-2-methoxycarbonyl-phenoxy)-propyl]-phenyl}-isoxazole-3-carboxylic acid
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C21H19NO7
 1
1
Ki = 23000 nM
   TI
   LI
   LO
   TS
CP0317539
5-[3-({2-[3-hydroxy-2-(methoxycarbonyl)phenoxy]ethyl}amino)phenyl]-1,2-oxazole-3-carboxylic acid
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C20H18N2O7
 1
1
Ki = 60300 nM
   TI
   LI
   LO
   TS