Brief Information of the Cell Line and Protein
Cell Line ID: CL000053 , COS-7
Synonyms
Cos-7
COS 7
Cos 7
COS7
Cos7
CV-1 in Origin Simian-7
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0224
Protein ID: PT02121 , Retinoic acid receptor gamma
Gene Name RARG
Organism Mus musculus, Mouse
Protein Classification Transcription factor
Uniprot ID P18911
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000053  Protein ID: PT02121
 
Compound ID Compound Name Compound Formula
CP0040160
9-cis-retinoic acid (9cRA)
   Show/Hide
C20H28O2
 1
1
EC50 = 0.6 nM
   TI
   LI
   LO
   TS
CP0479802
4-[5-(3,5-ditert-butylphenyl)-1,2,4-oxadiazol-3-yl]benzoic acid
   Show/Hide
C23H26N2O3
 1
1
EC50 = 2.8 nM
   TI
   LI
   LO
   TS
CP0552029
4-[3-(3,5-dichloro-4-ethoxyphenyl)-1,2,4-oxadiazol-5-yl]benzoic acid
   Show/Hide
C17H12Cl2N2O4
 1
1
EC50 = 5.4 nM
   TI
   LI
   LO
   TS
CP0412959
4-[5-(4,7-dimethyl-1-benzofuran-2-yl)-1,2,4-oxadiazol-3-yl]-3-fluorobenzoic acid
   Show/Hide
C19H13FN2O4
 1
1
EC50 = 5.5 nM
   TI
   LI
   LO
   TS
CP0081912
AC-261066
   Show/Hide
C17H20FNO4S
 1
1
EC50 = 5.8 nM
   TI
   LI
   LO
   TS
CP0559468
4-[5-(4,7-dimethyl-1-benzofuran-2-yl)-1,2,4-oxadiazol-3-yl]-2-methylbenzoic acid
   Show/Hide
C20H16N2O4
 1
1
EC50 = 6.4 nM
   TI
   LI
   LO
   TS
CP0552028
4-[5-(4,7-dimethyl-1-benzofuran-2-yl)-1,2,4-oxadiazol-3-yl]-2-fluorobenzoic acid
   Show/Hide
C19H13FN2O4
 1
1
EC50 = 7.3 nM
   TI
   LI
   LO
   TS
CP0439941
4-[5-[7-fluoro-4-(trifluoromethyl)-1-benzofuran-2-yl]-1,2,4-oxadiazol-3-yl]benzoic acid
   Show/Hide
C18H8F4N2O4
 1
1
EC50 = 7.6 nM
   TI
   LI
   LO
   TS
CP0412963
4-[5-(4,7-dimethyl-1-benzothiophen-2-yl)-1,2,4-oxadiazol-3-yl]benzoic acid
   Show/Hide
C19H14N2O3S
 1
1
EC50 = 9 nM
   TI
   LI
   LO
   TS
CP0420990
4-[5-(4,7-dimethyl-1,3-benzoxazol-2-yl)-1,2,4-oxadiazol-3-yl]benzoic acid
   Show/Hide
C18H13N3O4
 1
1
EC50 = 10 nM
   TI
   LI
   LO
   TS
CP0133700
6-[4-Methoxy-3-(1-methyl-cyclohexyl)-phenyl]-naphthalene-2-carboxylic acid
   Show/Hide
C25H26O3
 1
1
EC50 = 11 nM
   TI
   LI
   LO
   TS
CP0412962
4-[5-(3,5-dichloro-4-ethoxyphenyl)-1,2,4-oxadiazol-3-yl]benzoic acid
   Show/Hide
C17H12Cl2N2O4
 1
1
EC50 = 12 nM
   TI
   LI
   LO
   TS
CP0543673
4-[5-(4,7-dimethyl-1-benzofuran-2-yl)-1,2,4-oxadiazol-3-yl]-3-methylbenzoic acid
   Show/Hide
C20H16N2O4
 1
1
EC50 = 13 nM
   TI
   LI
   LO
   TS
CP0554174
4-[5-(4,7-dimethyl-1-benzofuran-2-yl)-1,2,4-oxadiazol-3-yl]benzoic acid
   Show/Hide
C19H14N2O4
 1
1
EC50 = 13 nM
   TI
   LI
   LO
   TS
CP0412961
4-[5-(3,5-dichloro-4-ethoxyphenyl)-1,3-oxazol-2-yl]benzoic acid
   Show/Hide
C18H13Cl2NO4
 1
1
EC50 = 45 nM
   TI
   LI
   LO
   TS
CP0543675
4-[5-(3,5-dichloro-4-ethoxyphenyl)-1,3,4-oxadiazol-2-yl]benzoic acid
   Show/Hide
C17H12Cl2N2O4
 1
1
EC50 = 150 nM
   TI
   LI
   LO
   TS
CP0439942
4-[4-(3,5-dichloro-4-ethoxyphenyl)-1,3-thiazol-2-yl]benzoic acid
   Show/Hide
C18H13Cl2NO3S
 1
1
EC50 = 160 nM
   TI
   LI
   LO
   TS
CP0412960
4-[(3,5-dichloro-4-ethoxybenzoyl)amino]benzoic acid
   Show/Hide
C16H13Cl2NO4
 1
1
EC50 = 30000 nM
   TI
   LI
   LO
   TS