Brief Information of the Cell Line and Protein
Cell Line ID: CL000053 , COS-7
Synonyms
Cos-7
COS 7
Cos 7
COS7
Cos7
CV-1 in Origin Simian-7
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0224
Protein ID: PT02120 , Retinoic acid receptor beta
Gene Name RARB
Organism Mus musculus, Mouse
Protein Classification Transcription factor
Uniprot ID P22605
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000053  Protein ID: PT02120
 
Compound ID Compound Name Compound Formula
CP0133700
6-[4-Methoxy-3-(1-methyl-cyclohexyl)-phenyl]-naphthalene-2-carboxylic acid
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C25H26O3
 1
1
EC50 = 0.83 nM
   TI
   LI
   LO
   TS
CP0040160
9-cis-retinoic acid (9cRA)
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C20H28O2
 1
1
EC50 = 1.2 nM
   TI
   LI
   LO
   TS
CP0479802
4-[5-(3,5-ditert-butylphenyl)-1,2,4-oxadiazol-3-yl]benzoic acid
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C23H26N2O3
 1
1
EC50 = 1.4 nM
   TI
   LI
   LO
   TS
CP0412962
4-[5-(3,5-dichloro-4-ethoxyphenyl)-1,2,4-oxadiazol-3-yl]benzoic acid
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C17H12Cl2N2O4
 1
1
EC50 = 1.5 nM
   TI
   LI
   LO
   TS
CP0554174
4-[5-(4,7-dimethyl-1-benzofuran-2-yl)-1,2,4-oxadiazol-3-yl]benzoic acid
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C19H14N2O4
 1
1
EC50 = 1.9 nM
   TI
   LI
   LO
   TS
CP0552028
4-[5-(4,7-dimethyl-1-benzofuran-2-yl)-1,2,4-oxadiazol-3-yl]-2-fluorobenzoic acid
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C19H13FN2O4
 1
1
EC50 = 2.2 nM
   TI
   LI
   LO
   TS
CP0439941
4-[5-[7-fluoro-4-(trifluoromethyl)-1-benzofuran-2-yl]-1,2,4-oxadiazol-3-yl]benzoic acid
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C18H8F4N2O4
 1
1
EC50 = 2.5 nM
   TI
   LI
   LO
   TS
CP0412963
4-[5-(4,7-dimethyl-1-benzothiophen-2-yl)-1,2,4-oxadiazol-3-yl]benzoic acid
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C19H14N2O3S
 1
1
EC50 = 3.4 nM
   TI
   LI
   LO
   TS
CP0412959
4-[5-(4,7-dimethyl-1-benzofuran-2-yl)-1,2,4-oxadiazol-3-yl]-3-fluorobenzoic acid
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C19H13FN2O4
 1
1
EC50 = 11 nM
   TI
   LI
   LO
   TS
CP0420990
4-[5-(4,7-dimethyl-1,3-benzoxazol-2-yl)-1,2,4-oxadiazol-3-yl]benzoic acid
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C18H13N3O4
 1
1
EC50 = 11 nM
   TI
   LI
   LO
   TS
CP0081912
AC-261066
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C17H20FNO4S
 1
1
EC50 = 12 nM
   TI
   LI
   LO
   TS
CP0559468
4-[5-(4,7-dimethyl-1-benzofuran-2-yl)-1,2,4-oxadiazol-3-yl]-2-methylbenzoic acid
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C20H16N2O4
 1
1
EC50 = 14 nM
   TI
   LI
   LO
   TS
CP0412961
4-[5-(3,5-dichloro-4-ethoxyphenyl)-1,3-oxazol-2-yl]benzoic acid
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C18H13Cl2NO4
 1
1
EC50 = 28 nM
   TI
   LI
   LO
   TS
CP0543673
4-[5-(4,7-dimethyl-1-benzofuran-2-yl)-1,2,4-oxadiazol-3-yl]-3-methylbenzoic acid
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C20H16N2O4
 1
1
EC50 = 47 nM
   TI
   LI
   LO
   TS
CP0543675
4-[5-(3,5-dichloro-4-ethoxyphenyl)-1,3,4-oxadiazol-2-yl]benzoic acid
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C17H12Cl2N2O4
 1
1
EC50 = 63 nM
   TI
   LI
   LO
   TS
CP0552029
4-[3-(3,5-dichloro-4-ethoxyphenyl)-1,2,4-oxadiazol-5-yl]benzoic acid
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C17H12Cl2N2O4
 1
1
EC50 = 110 nM
   TI
   LI
   LO
   TS
CP0439942
4-[4-(3,5-dichloro-4-ethoxyphenyl)-1,3-thiazol-2-yl]benzoic acid
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C18H13Cl2NO3S
 1
1
EC50 = 120 nM
   TI
   LI
   LO
   TS
CP0540813
4-[5-(3,5-dichloro-4-ethoxyphenyl)-1H-imidazol-2-yl]benzoic acid
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C18H14Cl2N2O3
 1
1
EC50 = 423 nM
   TI
   LI
   LO
   TS
CP0412960
4-[(3,5-dichloro-4-ethoxybenzoyl)amino]benzoic acid
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C16H13Cl2NO4
 1
1
EC50 = 1227 nM
   TI
   LI
   LO
   TS
CP0434040
4-[5-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,2,4-oxadiazol-3-yl]benzoic acid
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C23H24N2O3
 1
1
EC50 = 4200 nM
   TI
   LI
   LO
   TS