Brief Information of the Cell Line and Protein
Cell Line ID: CL000053 , COS-7
 Cell Line Info 
Synonyms
Cos-7
COS 7
Cos 7
COS7
Cos7
CV-1 in Origin Simian-7
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0224
Protein ID: PT01475 , Retinoic acid receptor alpha
 Protein Info 
Gene Name RARA
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID P10276
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000053
 Cell Line Info 
 Protein ID: PT01475
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0076822
 Compound Info 
4-(1,1,4,4-tetramethyl-1,2,3,4-tetrahydronaphthalene-7-carboxamido)benzoic acid
   Show/Hide
C22H25NO3
  1
1
EC50 = 0.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0259254
 Compound Info 
4-((5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethynyl)benzoic acid
   Show/Hide
C23H24O2
  1
1
EC50 = 0.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0040160
 Compound Info 
9-cis-retinoic acid (9cRA)
   Show/Hide
C20H28O2
  1
1
EC50 = 17 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0260468
 Compound Info 
ethyl 6-[2-(4,4-dimethyl-2,3-dihydrothiochromen-6-yl)ethynyl]pyridine-3-carboxylate
   Show/Hide
C21H21NO2S
  1
1
EC50 = 63 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0372939
 Compound Info 
5,5,8,8-tetramethyl-N-(4-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)phenyl)-5,6,7,8-tetrahydronaphthalene-2-carboxamide
   Show/Hide
C23H25N3O3
  1
1
EC50 = 520 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0372940
 Compound Info 
3-(3-((4-tert-butylphenyl)ethynyl)phenyl)-1,2,4-oxadiazol-5(4H)-one
   Show/Hide
C20H18N2O2
  1
1
EC50 > 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0387914
 Compound Info 
4-((4-tert-butylphenyl)ethynyl)benzoic acid
   Show/Hide
C19H18O2
  1
1
EC50 > 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0400216
 Compound Info 
3-(4-((4-tert-butylphenyl)ethynyl)phenyl)-1,2,4-oxadiazol-5(4H)-one
   Show/Hide
C20H18N2O2
  1
1
EC50 > 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0417761
 Compound Info 
3-(3-((5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethynyl)phenyl)-1,2,4-oxadiazol-5(4H)-one
   Show/Hide
C24H24N2O2
  1
1
EC50 > 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0474660
 Compound Info 
3-(4-((5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethynyl)phenyl)-1,2,4-oxadiazol-5(4H)-one
   Show/Hide
C24H24N2O2
  1
1
EC50 > 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS