Brief Information of the Compound and Protein
Compound Name
 Compound Info 
9-cis-retinoic acid (9cRA)
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 PubChem ID
CID: 444795
SID: 12014646
Canonical SMILES
C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O
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Compound Formula C20H28O2
Compound Structure
Protein Name
 Protein Info 
Retinoic acid receptor alpha
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group B
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Nuclear hormone receptor subfamily 1 group B member 1
Uniprot ID
P10276
Gene Name
RARA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
EC50 = 17 nM
   TI
   LI
   LO
   TS
CL000044 CV-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  3
1
EC50 = 7 nM
   TI
   LI
   LO
   TS
2
EC50 = 350 nM
   TI
   LI
   LO
   TS
3
EC50 = 436 nM
   TI
   LI
   LO
   TS
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
Kd = 2.3 nM
   TI
   LI
   LO
   TS
CL000035 NIH 3T3
 Cell Line Info 
Mus musculus (Mouse)  1
1
EC50 = 6.31 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 5 nM
2 EC50 = 16.1 nM
3 EC50 = 27 nM
4 EC50 = 50 nM
5 EC50 = 240 nM
6 EC50 = 350 nM
7 IC50 = 0.78 nM
8 IC50 = 0.89 nM
9 IC50 = 15 nM
10 IC50 = 9000 nM
11 Kd = 14 nM
12 Kd = 15 nM
13 Kd = 16 nM
14 Ki = 0.1 nM
15 Ki = 16 nM
16 Ki = 187 nM