Brief Information of the Cell Line and Protein
Cell Line ID: CL000053 , COS-7
 Cell Line Info 
Synonyms
Cos-7
COS 7
Cos 7
COS7
Cos7
CV-1 in Origin Simian-7
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0224
Protein ID: PT01202 , 5-hydroxytryptamine receptor 1B
 Protein Info 
Gene Name HTR1B
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P28222
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000053
 Cell Line Info 
 Protein ID: PT01202
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0288364
 Compound Info 
2'-Methyl-4'-(5-methyl-4,5-dihydro-[1,2,4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide
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C29H33N5O3
  1
1
Ki = 0.14 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0212546
 Compound Info 
1-[4-[(2-methylphenyl)methyl]piperazin-1-yl]-2-[8-(4-methylpiperazin-1-yl)naphthalen-2-yl]oxyethanone
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C29H36N4O2
  1
1
Ki = 0.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0154534
 Compound Info 
2-[8-(4-Methyl-piperazin-1-yl)-naphthalen-2-yloxy]-1-(4-o-tolyl-piperazin-1-yl)-ethanone
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C28H34N4O2
  1
1
Ki = 0.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0097451
 Compound Info 
2-[4-[2-[8-(4-methylpiperazin-1-yl)naphthalen-2-yl]oxyacetyl]piperazin-1-yl]benzonitrile
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C28H31N5O2
  1
1
Ki = 0.38 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0047323
 Compound Info 
2-[8-(4-methylpiperazin-1-yl)naphthalen-2-yl]oxy-1-(4-naphthalen-1-ylpiperazin-1-yl)ethanone
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C31H34N4O2
  1
1
Ki = 0.43 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0144898
 Compound Info 
1-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazin-1-yl]-2-[8-(4-methyl-piperazin-1-yl)-naphthalen-2-yloxy]-ethanone
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C29H34N4O4
  1
1
Ki = 0.43 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0371225
 Compound Info 
1-[4-(2,3-Dimethoxy-phenyl)-piperazin-1-yl]-2-[8-(4-methyl-piperazin-1-yl)-naphthalen-2-yloxy]-ethanone
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C29H36N4O4
  1
1
Ki = 0.44 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0168336
 Compound Info 
2-[8-(4-Methyl-piperazin-1-yl)-naphthalen-2-yloxy]-1-[4-(2,4,6-trimethyl-phenyl)-piperazin-1-yl]-ethanone
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C30H38N4O2
  1
1
Ki = 1.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0043049
 Compound Info 
1-(7-Methoxy-naphthalen-2-yl)-piperazine
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C15H18N2O
  1
1
Ki = 2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0061753
 Compound Info 
1-NP
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C14H16N2
  1
1
Ki = 10.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS