Brief Information of the Cell Line and Protein
Cell Line ID: CL000053 , COS-7
Synonyms
Cos-7
COS 7
Cos 7
COS7
Cos7
CV-1 in Origin Simian-7
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0224
Protein ID: PT01171 , Prostaglandin D2 receptor 2
Gene Name PTGDR2
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID Q9Y5Y4
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000053  Protein ID: PT01171
 
Compound ID Compound Name Compound Formula
CP0375782
2-(2-(4-chlorobenzyl)-4-(4-phenoxyphenyl)thiazol-5-yl)acetic acid
   Show/Hide
C24H18ClNO3S
 1
1
IC50 = 3.7 nM
   TI
   LI
   LO
   TS
CP0499141
2-(2-(biphenyl-2-ylmethyl)-4-(4-fluorophenyl)thiazol-5-yl)acetic acid
   Show/Hide
C24H18FNO2S
 1
1
IC50 = 24 nM
   TI
   LI
   LO
   TS
CP0510466
2-(2-(2-(benzo[d][1,3]dioxol-5-yl)benzyl)-4-(4-fluorophenyl)thiazol-5-yl)acetic acid
   Show/Hide
C25H18FNO4S
 1
1
IC50 = 24 nM
   TI
   LI
   LO
   TS
CP0373383
2-(4-(biphenyl-4-yl)-2-phenylthiazol-5-yl)acetic acid
   Show/Hide
C23H17NO2S
 1
1
IC50 = 38 nM
   TI
   LI
   LO
   TS
CP0401656
2-(4-(4-fluorophenyl)-2-((3'-methoxybiphenyl-2-yl)methyl)thiazol-5-yl)acetic acid
   Show/Hide
C25H20FNO3S
 1
1
IC50 = 40 nM
   TI
   LI
   LO
   TS
CP0401657
2-(2-(biphenyl-2-ylmethyl)-4-(4-chlorophenyl)thiazol-5-yl)acetic acid
   Show/Hide
C24H18ClNO2S
 1
1
IC50 = 41 nM
   TI
   LI
   LO
   TS
CP0415100
2-(4-(4-chlorophenyl)-2-(naphthalen-2-ylmethyl)thiazol-5-yl)acetic acid
   Show/Hide
C22H16ClNO2S
 1
1
IC50 = 41 nM
   TI
   LI
   LO
   TS
CP0497048
2-(2-(2-methoxyphenylamino)-4-(4-phenoxyphenyl)thiazol-5-yl)acetic acid
   Show/Hide
C24H20N2O4S
 1
1
IC50 = 49 nM
   TI
   LI
   LO
   TS
CP0383300
2-(2-(4-chlorobenzyl)-4-(4-chlorophenyl)thiazol-5-yl)acetic acid
   Show/Hide
C18H13Cl2NO2S
 1
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
CP0383298
2-(4-(4-fluorophenyl)-2-((4'-methoxybiphenyl-2-yl)methyl)thiazol-5-yl)acetic acid
   Show/Hide
C25H20FNO3S
 1
1
IC50 = 72 nM
   TI
   LI
   LO
   TS
CP0373387
2-(4-(4-phenoxyphenyl)-2-(phenylamino)thiazol-5-yl)acetic acid
   Show/Hide
C23H18N2O3S
 1
1
IC50 = 84 nM
   TI
   LI
   LO
   TS
CP0421572
2-(2-(4-chlorobenzyl)-4-phenylthiazol-5-yl)acetic acid
   Show/Hide
C18H14ClNO2S
 1
1
IC50 = 88 nM
   TI
   LI
   LO
   TS
CP0430743
2-(2-(4-fluorophenylamino)-4-(4-phenoxyphenyl)thiazol-5-yl)acetic acid
   Show/Hide
C23H17FN2O3S
 1
1
IC50 = 89 nM
   TI
   LI
   LO
   TS
CP0373540
2-(4-(4-chlorophenyl)-2-(4-phenoxyphenyl)thiazol-5-yl)acetic acid
   Show/Hide
C23H16ClNO3S
 1
1
IC50 = 93 nM
   TI
   LI
   LO
   TS
CP0499105
2-(2-(naphthalen-2-ylamino)-4-(4-phenoxyphenyl)thiazol-5-yl)acetic acid
   Show/Hide
C27H20N2O3S
 1
1
IC50 = 94 nM
   TI
   LI
   LO
   TS
CP0050007
2-(4-(4-chlorophenyl)-2-(phenylamino)thiazol-5-yl)acetic acid
   Show/Hide
C17H13ClN2O2S
 1
1
IC50 = 100 nM
   TI
   LI
   LO
   TS
CP0383274
2-(2-(2-chlorophenylamino)-4-(4-phenoxyphenyl)thiazol-5-yl)acetic acid
   Show/Hide
C23H17ClN2O3S
 1
1
IC50 = 130 nM
   TI
   LI
   LO
   TS
CP0430741
2-(2-benzyl-4-(4-fluorophenyl)thiazol-5-yl)acetic acid
   Show/Hide
C18H14FNO2S
 1
1
IC50 = 140 nM
   TI
   LI
   LO
   TS
CP0373555
2-(4-(4-fluorophenyl)-2-((3'-(trifluoromethoxy)biphenyl-2-yl)methyl)thiazol-5-yl)acetic acid
   Show/Hide
C25H17F4NO3S
 1
1
IC50 = 160 nM
   TI
   LI
   LO
   TS
CP0415087
2-(2-(4-phenoxyphenyl)-4-phenylthiazol-5-yl)acetic acid
   Show/Hide
C23H17NO3S
 1
1
IC50 = 160 nM
   TI
   LI
   LO
   TS
CP0510459
2-(4-(4-chlorophenyl)-2-(2-phenoxybenzyl)thiazol-5-yl)acetic acid
   Show/Hide
C24H18ClNO3S
 1
1
IC50 = 160 nM
   TI
   LI
   LO
   TS
CP0383356
2-(4-(4-fluorophenyl)-2-((2'-methoxybiphenyl-2-yl)methyl)thiazol-5-yl)acetic acid
   Show/Hide
C25H20FNO3S
 1
1
IC50 = 170 nM
   TI
   LI
   LO
   TS
CP0500156
2-(2-((4'-cyanobiphenyl-2-yl)methyl)-4-(4-fluorophenyl)thiazol-5-yl)acetic acid
   Show/Hide
C25H17FN2O2S
 1
1
IC50 = 170 nM
   TI
   LI
   LO
   TS
CP0373382
2-(2-benzyl-4-(4-chlorophenyl)thiazol-5-yl)acetic acid
   Show/Hide
C18H14ClNO2S
 1
1
IC50 = 180 nM
   TI
   LI
   LO
   TS
CP0373386
2-(2-(2-fluorophenylamino)-4-(4-phenoxyphenyl)thiazol-5-yl)acetic acid
   Show/Hide
C23H17FN2O3S
 1
1
IC50 = 210 nM
   TI
   LI
   LO
   TS
CP0493308
2-(2-(4-chlorophenyl)-4-(4-methoxyphenyl)thiazol-5-yl)acetic acid
   Show/Hide
C18H14ClNO3S
 1
1
IC50 = 210 nM
   TI
   LI
   LO
   TS
CP0502383
2-(4-(4-bromophenyl)-2-(naphthalen-2-ylamino)thiazol-5-yl)acetic acid
   Show/Hide
C21H15BrN2O2S
 1
1
IC50 = 220 nM
   TI
   LI
   LO
   TS
CP0421571
2-(2-(4-methylbenzyl)-4-phenylthiazol-5-yl)acetic acid
   Show/Hide
C19H17NO2S
 1
1
IC50 = 250 nM
   TI
   LI
   LO
   TS
CP0453089
2-(4-(biphenyl-4-yl)-2-(2-methoxyphenylamino)thiazol-5-yl)acetic acid
   Show/Hide
C24H20N2O3S
 1
1
IC50 = 310 nM
   TI
   LI
   LO
   TS
CP0383004
2-(2-(3,4-dimethoxybenzyl)-4-phenylthiazol-5-yl)acetic acid
   Show/Hide
C20H19NO4S
 1
1
IC50 = 330 nM
   TI
   LI
   LO
   TS
CP0383273
2-(2-((3'-cyanobiphenyl-2-yl)methyl)-4-(4-fluorophenyl)thiazol-5-yl)acetic acid
   Show/Hide
C25H17FN2O2S
 1
1
IC50 = 340 nM
   TI
   LI
   LO
   TS
CP0045666
2-(4-phenyl-2-(phenylamino)thiazol-5-yl)acetic acid
   Show/Hide
C17H14N2O2S
 1
1
IC50 = 350 nM
   TI
   LI
   LO
   TS
CP0517561
2-(4-(4-bromophenyl)-2-(2-methoxyphenyl)thiazol-5-yl)acetic acid
   Show/Hide
C18H14BrNO3S
 1
1
IC50 = 350 nM
   TI
   LI
   LO
   TS
CP0430794
2-(2-(4-chlorobenzyl)-4-(4-methoxyphenyl)thiazol-5-yl)acetic acid
   Show/Hide
C19H16ClNO3S
 1
1
IC50 = 360 nM
   TI
   LI
   LO
   TS
CP0517560
2-(4-(4-bromophenyl)-2-(4-methoxyphenyl)thiazol-5-yl)acetic acid
   Show/Hide
C18H14BrNO3S
 1
1
IC50 = 390 nM
   TI
   LI
   LO
   TS
CP0401661
2-(4-(4-chlorophenyl)-2-(2-methoxyphenylamino)thiazol-5-yl)acetic acid
   Show/Hide
C18H15ClN2O3S
 1
1
IC50 = 450 nM
   TI
   LI
   LO
   TS
CP0383304
2-(4-(4-bromophenyl)-2-(4-(dimethylamino)phenyl)thiazol-5-yl)acetic acid
   Show/Hide
C19H17BrN2O2S
 1
1
IC50 = 460 nM
   TI
   LI
   LO
   TS
CP0430749
2-(4-(4-methoxyphenyl)-2-(4-phenoxyphenyl)thiazol-5-yl)acetic acid
   Show/Hide
C24H19NO4S
 1
1
IC50 = 470 nM
   TI
   LI
   LO
   TS
CP0477653
2-(4-(4-chlorophenyl)-2-(furan-2-yl)thiazol-5-yl)acetic acid
   Show/Hide
C15H10ClNO3S
 1
1
IC50 = 550 nM
   TI
   LI
   LO
   TS
CP0388167
2-(4-(4-chlorophenyl)-2-phenylthiazol-5-yl)acetic acid
   Show/Hide
C17H12ClNO2S
 1
1
IC50 = 550 nM
   TI
   LI
   LO
   TS
CP0485993
2-(4-(4-fluorophenyl)-2-(phenylamino)thiazol-5-yl)acetic acid
   Show/Hide
C17H13FN2O2S
 1
1
IC50 = 650 nM
   TI
   LI
   LO
   TS
CP0517559
2-(4-(biphenyl-4-yl)-2-(phenylamino)thiazol-5-yl)acetic acid
   Show/Hide
C23H18N2O2S
 1
1
IC50 = 660 nM
   TI
   LI
   LO
   TS
CP0417837
2-(2-(2-bromobenzyl)-4-(4-fluorophenyl)thiazol-5-yl)acetic acid
   Show/Hide
C18H13BrFNO2S
 1
1
IC50 = 700 nM
   TI
   LI
   LO
   TS
CP0430745
2-(4-(4-chlorophenyl)-2-(4-(trifluoromethyl)phenylamino)thiazol-5-yl)acetic acid
   Show/Hide
C18H12ClF3N2O2S
 1
1
IC50 = 700 nM
   TI
   LI
   LO
   TS
CP0401659
2-(4-(4-chlorophenyl)-2-(p-tolylamino)thiazol-5-yl)acetic acid
   Show/Hide
C18H15ClN2O2S
 1
1
IC50 = 750 nM
   TI
   LI
   LO
   TS
CP0430798
2-(2-(4-methoxyphenyl)-4-phenylthiazol-5-yl)acetic acid
   Show/Hide
C18H15NO3S
 1
1
IC50 = 820 nM
   TI
   LI
   LO
   TS
CP0453093
2-(4-(4-fluorophenyl)-2-phenylthiazol-5-yl)acetic acid
   Show/Hide
C17H12FNO2S
 1
1
IC50 = 860 nM
   TI
   LI
   LO
   TS
CP0493304
2-(2,4-diphenylthiazol-5-yl)acetic acid
   Show/Hide
C17H13NO2S
 1
1
IC50 = 870 nM
   TI
   LI
   LO
   TS
CP0383013
2-(4-(biphenyl-4-yl)-2-(4-chlorophenylamino)thiazol-5-yl)acetic acid
   Show/Hide
C23H17ClN2O2S
 1
1
IC50 = 940 nM
   TI
   LI
   LO
   TS
CP0488943
2-(2-(4-methoxyphenylamino)-4-phenylthiazol-5-yl)acetic acid
   Show/Hide
C18H16N2O3S
 1
1
IC50 = 940 nM
   TI
   LI
   LO
   TS
CP0488954
2-(2-(4-chlorophenylamino)-4-(4-fluorophenyl)thiazol-5-yl)acetic acid
   Show/Hide
C17H12ClFN2O2S
 1
1
IC50 = 960 nM
   TI
   LI
   LO
   TS
CP0180268
2-(2-(4-chlorophenyl)-4-phenylthiazol-5-yl)acetic acid
   Show/Hide
C17H12ClNO2S
 1
1
IC50 = 990 nM
   TI
   LI
   LO
   TS
CP0493306
2-(2-(4-chlorophenyl)-4-(2,4-dimethylphenyl)thiazol-5-yl)acetic acid
   Show/Hide
C19H16ClNO2S
 1
1
IC50 = 990 nM
   TI
   LI
   LO
   TS
CP0471569
2-(4-(4-chlorophenyl)-2-(4-isopropylphenylamino)thiazol-5-yl)acetic acid
   Show/Hide
C20H19ClN2O2S
 1
1
IC50 = 1200 nM
   TI
   LI
   LO
   TS
CP0485994
2-(4-(4-ethylphenyl)-2-phenylthiazol-5-yl)acetic acid
   Show/Hide
C19H17NO2S
 1
1
IC50 = 1300 nM
   TI
   LI
   LO
   TS
CP0417836
2-(4-(4-ethylphenyl)-2-(2-methoxyphenyl)thiazol-5-yl)acetic acid
   Show/Hide
C20H19NO3S
 1
1
IC50 = 1400 nM
   TI
   LI
   LO
   TS
CP0383303
2-(2-(4-fluorophenyl)-4-phenylthiazol-5-yl)acetic acid
   Show/Hide
C17H12FNO2S
 1
1
IC50 = 1500 nM
   TI
   LI
   LO
   TS
CP0430747
2-(4-(4-fluorophenyl)-2-(2-methoxyphenylamino)thiazol-5-yl)acetic acid
   Show/Hide
C18H15FN2O3S
 1
1
IC50 = 1500 nM
   TI
   LI
   LO
   TS
CP0373368
2-(4-(4-methoxyphenyl)-2-(phenylamino)thiazol-5-yl)acetic acid
   Show/Hide
C18H16N2O3S
 1
1
IC50 = 1900 nM
   TI
   LI
   LO
   TS
CP0485995
2-(2,4-bis(4-methoxyphenyl)thiazol-5-yl)acetic acid
   Show/Hide
C19H17NO4S
 1
1
IC50 = 4100 nM
   TI
   LI
   LO
   TS
CP0452734
2-(4-(4-chlorophenyl)-2-methylthiazol-5-yl)acetic acid
   Show/Hide
C12H10ClNO2S
 1
1
IC50 = 5500 nM
   TI
   LI
   LO
   TS
CP0489547
2-(4-(4-methoxyphenyl)-2-phenylthiazol-5-yl)acetic acid
   Show/Hide
C18H15NO3S
 1
1
IC50 = 7000 nM
   TI
   LI
   LO
   TS