Brief Information of the Cell Line and Protein
Cell Line ID: CL000045 , A-375
 Cell Line Info 
Synonyms
A 375
A375
A375-MEL
A375-mel
A375mel
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0132
Protein ID: PT02611 , Ceramide glucosyltransferase
 Protein Info 
Gene Name UGCG
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID Q16739
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000045
 Cell Line Info 
 Protein ID: PT02611
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0579431
 Compound Info 
N-(1-azabicyclo[2.2.2]octan-3-yl)-5-chloro-7-[2-(2-fluoroethoxy)phenyl]-1-benzofuran-2-carboxamide
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C24H24ClFN2O3
  1
1
EC50 = 0.02 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0579374
 Compound Info 
N-(1-azabicyclo[2.2.2]octan-3-yl)-7-(2-butoxyphenyl)-1-benzofuran-2-carboxamide
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C26H30N2O3
  1
1
EC50 = 0.021 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0578616
 Compound Info 
N-(1,6-naphthyridin-2-yl)-7-[2-(2,2,2-trifluoroethoxy)phenyl]-1-benzofuran-2-carboxamide
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C25H16F3N3O3
  1
1
EC50 = 0.023 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0569105
 Compound Info 
5-chloro-7-(5-cyano-2-propan-2-yloxyphenyl)-N-(3-hydroxycyclobutyl)-1-benzofuran-2-carboxamide
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C23H21ClN2O4
  1
1
EC50 = 0.044 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0569901
 Compound Info 
N-(1-azabicyclo[2.2.2]octan-3-yl)-7-(2-propoxyphenyl)-1-benzofuran-2-carboxamide
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C25H28N2O3
  1
1
EC50 = 0.044 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0567992
 Compound Info 
7-(2-chloro-5-cyanophenyl)-N-[(1S,3R)-3-hydroxycyclopentyl]-1-benzofuran-2-carboxamide
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C21H17ClN2O3
  1
1
EC50 = 0.047 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS