Brief Information of the Cell Line and Protein
Cell Line ID: CL000040 , THP-1
 Cell Line Info 
Synonyms
THP1
THP 1
THPI
THP-1(ATCC)
THP-1-O
O-THP-1
Tohoku Hospital Pediatrics-1
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0006
Protein ID: PT01008 , Macrophage colony-stimulating factor 1 receptor
 Protein Info 
Gene Name CSF1R
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P07333
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000040
 Cell Line Info 
 Protein ID: PT01008
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0579995
 Compound Info 
5-[6-methyl-5-[2-(1-methylpyrazol-4-yl)pyridin-4-yl]oxypyridin-2-yl]-2-(propan-2-ylamino)-1H-pyrimidin-6-one
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C22H23N7O2
  1
1
IC50 = 8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0133124
 Compound Info 
5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-[[6-(trifluoromethyl)pyridin-3-yl]methyl]pyridin-2-amine
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C20H15ClF3N5
  1
1
IC50 = 17 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0540361
 Compound Info 
DCC-3014
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C23H25N7O2
  1
1
IC50 = 27 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0545184
 Compound Info 
2-(cyclopropylamino)-5-[6-methyl-5-[2-(1-methylpyrazol-4-yl)pyridin-4-yl]oxypyridin-2-yl]-1H-pyrimidin-6-one
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C22H21N7O2
  1
1
IC50 = 35 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0568954
 Compound Info 
2-(cyclopropylamino)-3-methyl-5-[6-methyl-5-[2-(1-methylpyrazol-4-yl)pyridin-4-yl]oxypyridin-2-yl]pyrimidin-4-one
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C23H23N7O2
  1
1
IC50 = 68 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS