Brief Information of the Cell Line and Protein
Cell Line ID: CL000035 , NIH 3T3
 Cell Line Info 
Synonyms
NIH/3T3
NIH-3T3
NIH3T3
3T3
3T3NIH
3T3-Swiss
Swiss-3T3
Swiss/3T3
Swiss 3T3
Swiss3T3
Category Spontaneously immortalized cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_0594
Protein ID: PT04369 , Mas-related G-protein coupled receptor member X1
 Protein Info 
Gene Name MRGPRX1
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID Q96LB2
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000035
 Cell Line Info 
 Protein ID: PT04369
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0862304
 Compound Info 
(alphaS)-alpha-[3-[(aminoiminomethyl)amino]propyl]-2-(3-phenoxyphenyl)-5-[[[2-(2-pyridinyl)ethyl]amino]carbonyl]-1H-benzimidazole-1-acetamide
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C33H34N8O3
  1
1
EC50 = 158.49 nM
 Bioactivity Info 
   TI
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CP0850466
 Compound Info 
(S)-1-(1-amino-5-guanidino-1-oxopentan-2-yl)-2-(3-phenoxyphenyl)-N-(3-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxamide
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C34H32F3N7O3
  1
1
EC50 = 398.11 nM
 Bioactivity Info 
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CP0850729
 Compound Info 
(alphaS)-alpha-[3-[(aminoiminomethyl)amino]propyl]-5-[[3-methyl-4-(3-methylphenyl)-1-piperazinyl]carbonyl]-2-(3-phenoxyphenyl)-1H-benzimidazole-1-acetamide
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C38H42N8O3
  1
1
EC50 = 630.96 nM
 Bioactivity Info 
   TI
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CP0850730
 Compound Info 
(S)-1-(1-amino-5-guanidino-1-oxopentan-2-yl)-N-butyl-2-(3-phenoxyphenyl)-1H-benzo[d]imidazole-5-carboxamide
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C30H35N7O3
  1
1
EC50 = 630.96 nM
 Bioactivity Info 
   TI
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CP0848745
 Compound Info 
(S)-1-(1-amino-5-guanidino-1-oxopentan-2-yl)-N-(4-methoxyphenyl)-2-(3-phenoxyphenyl)-1H-benzo[d]imidazole-5-carboxamide
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C33H33N7O4
  1
1
EC50 = 794.33 nM
 Bioactivity Info 
   TI
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CP0850467
 Compound Info 
(alphaS)-alpha-[3-[(aminoiminomethyl)amino]propyl]-5-[[4-(4-fluorophenyl)-1-piperazinyl]carbonyl]-2-(3-phenoxyphenyl)-1H-benzimidazole-1-acetamide
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C36H37FN8O3
  1
1
EC50 = 1000 nM
 Bioactivity Info 
   TI
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CP0850468
 Compound Info 
(alphaS)-alpha-[3-[(aminoiminomethyl)amino]propyl]-5-[[methyl[2-(2-pyridinyl)ethyl]amino]carbonyl]-2-(3-phenoxyphenyl)-1H-benzimidazole-1-acetamide
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C34H36N8O3
  1
1
EC50 = 1000 nM
 Bioactivity Info 
   TI
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CP0848746
 Compound Info 
(R)-5-guanidino-2-(5-(morpholine-4-carbonyl)-2-(3-phenoxyphenyl)-1H-benzo[d]imidazol-1-yl)pentanamide
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C30H33N7O4
  1
1
EC50 = 1584.89 nM
 Bioactivity Info 
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CP0857660
 Compound Info 
(R)-1-(1-amino-5-guanidino-1-oxopentan-2-yl)-N-(1H-indazol-6-yl)-2-(3-phenoxyphenyl)-1H-benzo[d]imidazole-5-carboxamide
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C33H31N9O3
  1
1
EC50 = 2511.89 nM
 Bioactivity Info 
   TI
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CP0866316
 Compound Info 
(S)-1-(1-amino-5-guanidino-1-oxopentan-2-yl)-2-(3-phenoxyphenyl)-N-(thiazol-2-yl)-1H-benzo[d]imidazole-5-carboxamide
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C29H28N8O3S
  1
1
EC50 = 2511.89 nM
 Bioactivity Info 
   TI
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   TS