General Information of the Compound
Compound ID
CP0850468
Compound Name
(alphaS)-alpha-[3-[(aminoiminomethyl)amino]propyl]-5-[[methyl[2-(2-pyridinyl)ethyl]amino]carbonyl]-2-(3-phenoxyphenyl)-1H-benzimidazole-1-acetamide
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Structure
Formula
C34H36N8O3
Molecular Weight
604.715
Canonical SMILES
CN(CCc1ccccn1)C(=O)c1ccc2c(c1)nc(-c1cccc(Oc3ccccc3)c1)n2[C@@H](CCCNC(=N)N)C(N)=O
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InChI
InChI=1S/C34H36N8O3/c1-41(20-17-25-10-5-6-18-38-25)33(44)24-15-16-29-28(22-24)40-32(42(29)30(31(35)43)14-8-19-39-34(36)37)23-9-7-13-27(21-23)45-26-11-3-2-4-12-26/h2-7,9-13,15-16,18,21-22,30H,8,14,17,19-20H2,1H3,(H2,35,43)(H4,36,37,39)/t30-/m0/s1
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InChIKey
BRYPYUOISATLPO-PMERELPUSA-N
Physicochemical Property
logP
4.49497
Rotatable Bonds
13
Heavy Atom Count
45
Polar Areas
165.24
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
7
Complexity
45

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 59819672
ChEMBL ID
CHEMBL3719266
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00634, Mas-related G protein-coupled receptor X1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
EC50 = 1258.93 nM
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Protein ID: PT04369, Mas-related G-protein coupled receptor member X1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
EC50 = 1000 nM
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