General Information of the Protein
Protein ID
PT00634
Protein Name
Mas-related G protein-coupled receptor X1
Sequence
MDPTIPALDTKLTPINRTEATPCYKQTLSFMGLTCIISLVGLTGNAVVLWLLGFRMHKNAFSIYILNLSMADFLFLSGRFIYSLLSFISVPQTISKILYPVTMFSYFAGLSFLSAMSTERCLSVLWPMWYRCRRPTHLSVVLCVLLWVLSLLRSILEWMFCGFLFSGADPVWCQTSDFITVAWLIFLCVVLCVSSLVLVIRILCGSRKMPLTRLYVTILLTVLVFLLCGLPFGVQFFLFFWIHVDWKVLYCHVHLVSMFLAALNSSANPIIYFFVGSFRQRQNRQNLRLVLQRALQDTPEVDEGGGRLPEETLELSGSRLEQ
    Show/Hide
Organism
Macaca mulatta, Rhesus macaque
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
Uniprot ID
Q1L4E8
Subcellular Location
Cell membrane
Map of Molecular Bioactivity Related to the Protein
Map of Molecular Bioactivity Related to the Protein

Protein
Cell Line
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000035 , NIH 3T3
 Cell Line Info 
Compound ID Compound Name Compound Formula
CP0850468
 Compound Info 
(alphaS)-alpha-[3-[(aminoiminomethyl)amino]propyl]-5-[[methyl[2-(2-pyridinyl)ethyl]amino]carbonyl]-2-(3-phenoxyphenyl)-1H-benzimidazole-1-acetamide
   Show/Hide
C34H36N8O3
  1
1
EC50 = 1258.93 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0850467
 Compound Info 
(alphaS)-alpha-[3-[(aminoiminomethyl)amino]propyl]-5-[[4-(4-fluorophenyl)-1-piperazinyl]carbonyl]-2-(3-phenoxyphenyl)-1H-benzimidazole-1-acetamide
   Show/Hide
C36H37FN8O3
  1
1
EC50 = 1584.89 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0850729
 Compound Info 
(alphaS)-alpha-[3-[(aminoiminomethyl)amino]propyl]-5-[[3-methyl-4-(3-methylphenyl)-1-piperazinyl]carbonyl]-2-(3-phenoxyphenyl)-1H-benzimidazole-1-acetamide
   Show/Hide
C38H42N8O3
  1
1
EC50 = 1584.89 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0862304
 Compound Info 
(alphaS)-alpha-[3-[(aminoiminomethyl)amino]propyl]-2-(3-phenoxyphenyl)-5-[[[2-(2-pyridinyl)ethyl]amino]carbonyl]-1H-benzimidazole-1-acetamide
   Show/Hide
C33H34N8O3
  1
1
EC50 = 2511.89 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Similar Protein(s) and Bioactivity Statistics
50% Identity
Protein ID Protein Name Protein Organism
PT06353 Mas-related G-protein coupled receptor member X4 Homo sapiens, Human
 Protein Info