General Information of the Compound
Compound ID
CP0848746
Compound Name
(R)-5-guanidino-2-(5-(morpholine-4-carbonyl)-2-(3-phenoxyphenyl)-1H-benzo[d]imidazol-1-yl)pentanamide
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Structure
Formula
C30H33N7O4
Molecular Weight
555.639
Canonical SMILES
N=C(N)NCCC[C@H](C(N)=O)n1c(-c2cccc(Oc3ccccc3)c2)nc2cc(C(=O)N3CCOCC3)ccc21
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InChI
InChI=1S/C30H33N7O4/c31-27(38)26(10-5-13-34-30(32)33)37-25-12-11-21(29(39)36-14-16-40-17-15-36)19-24(25)35-28(37)20-6-4-9-23(18-20)41-22-7-2-1-3-8-22/h1-4,6-9,11-12,18-19,26H,5,10,13-17H2,(H2,31,38)(H4,32,33,34)/t26-/m1/s1
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InChIKey
HEACHFYTODVTGR-AREMUKBSSA-N
Physicochemical Property
logP
3.25767
Rotatable Bonds
10
Heavy Atom Count
41
Polar Areas
161.58
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
7
Complexity
41

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 89224504
ChEMBL ID
CHEMBL3719296
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT04369, Mas-related G-protein coupled receptor member X1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
EC50 = 1584.89 nM
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