Brief Information of the Cell Line and Protein
Cell Line ID: CL000026 , CHO-K1
Synonyms
CHO K1
CHOK1
CHO cell clone K1
GM15452
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0214
Protein ID: PT06327 , Sodium-dependent phosphate transport protein 2B
Gene Name SLC34A2
Organism Homo sapiens, Human
Protein Classification Transporter
Uniprot ID O95436
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000026  Protein ID: PT06327
 
Compound ID Compound Name Compound Formula
CP0573199
4-[ethyl-[3-[[2-[[4-[2-[4-(methylsulfamoylcarbamoyl)phenyl]ethyl]phenyl]carbamoyl]-6-piperidin-1-ylpyridin-3-yl]carbamoyl]phenyl]sulfonylamino]cyclohexane-1-carboxylic acid
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C43H51N7O9S2
 1
1
IC50 = 21 nM
   TI
   LI
   LO
   TS
CP0572734
4-[2-[4-[[3-[[3-[[2-[3-carboxypropanoyl(methyl)amino]ethyl-pentan-3-ylamino]methyl]benzoyl]amino]-6-piperidin-1-ylpyridine-2-carbonyl]amino]phenyl]ethyl]benzoic acid
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C46H56N6O7
 1
1
IC50 = 36 nM
   TI
   LI
   LO
   TS
CP0550252
4-[3-[4-[[2-[[3-[[2-[3-carboxypropanoyl(methyl)amino]ethyl-pentan-3-ylamino]methyl]benzoyl]amino]-1H-indole-3-carbonyl]amino]phenyl]propyl]benzoic acid
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C45H51N5O7
 1
1
IC50 = 71 nM
   TI
   LI
   LO
   TS
CP0577666
4-[2-[4-[[3-[[3-[(4-carboxycyclohexyl)-ethylsulfamoyl]benzoyl]amino]-6-piperidin-1-ylpyridine-2-carbonyl]amino]phenyl]ethyl]benzoic acid
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C42H47N5O8S
 1
1
IC50 = 77 nM
   TI
   LI
   LO
   TS
CP0579870
4-[3-[4-[[2-[[3-[[2-[3-carboxypropanoyl(methyl)amino]ethyl-heptan-4-ylamino]methyl]benzoyl]amino]-1H-indole-3-carbonyl]amino]phenyl]propyl]benzoic acid;hydrochloride
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C47H56ClN5O7
 1
1
IC50 = 78 nM
   TI
   LI
   LO
   TS
CP0572733
4-[2-[4-[[3-[[3-[[2-[3-carboxypropanoyl(methyl)amino]ethyl-pentan-3-ylamino]methyl]benzoyl]amino]-6-methoxypyridine-2-carbonyl]amino]phenyl]ethyl]benzoic acid
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C42H49N5O8
 1
1
IC50 = 107 nM
   TI
   LI
   LO
   TS
CP0577078
4-[2-[4-[[3-[[3-[ethyl-[4-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethylcarbamoyl]cyclohexyl]sulfamoyl]benzoyl]amino]-6-piperidin-1-ylpyridine-2-carbonyl]amino]phenyl]ethyl]benzoic acid
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C50H64N6O11S
 1
1
IC50 = 141 nM
   TI
   LI
   LO
   TS
CP0577667
4-[2-[4-[[3-[[3-[ethyl-[4-(methylsulfamoylcarbamoyl)cyclohexyl]sulfamoyl]benzoyl]amino]-6-piperidin-1-ylpyridine-2-carbonyl]amino]phenyl]ethyl]benzoic acid
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C43H51N7O9S2
 1
1
IC50 = 147 nM
   TI
   LI
   LO
   TS
CP0578367
4-[2-[4-[[3-[[3-[[2-[3-carboxypropanoyl(methyl)amino]ethyl-pentan-3-ylamino]methyl]benzoyl]amino]-6-(dimethylamino)pyridine-2-carbonyl]amino]phenyl]ethyl]benzoic acid
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C43H52N6O7
 1
1
IC50 = 161 nM
   TI
   LI
   LO
   TS
CP0577236
4-[4-[[3-[[3-[[2-[3-carboxypropanoyl(methyl)amino]ethyl-pentan-3-ylamino]methyl]benzoyl]amino]-6-piperidin-1-ylpyridine-2-carbonyl]amino]phenoxy]benzoic acid
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C44H52N6O8
 1
1
IC50 = 162 nM
   TI
   LI
   LO
   TS
CP0574536
4-[3-[4-[[2-[[3-[[2-[[4-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethylamino]-4-oxobutanoyl]-methylamino]ethyl-pentan-3-ylamino]methyl]benzoyl]amino]-1H-indole-3-carbonyl]amino]phenyl]propyl]benzoic acid
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C53H68N6O10
 1
1
IC50 = 166 nM
   TI
   LI
   LO
   TS
CP0578502
4-[methyl-[2-[[3-[[2-[[4-[2-[4-(methylsulfamoylcarbamoyl)phenyl]ethyl]phenyl]carbamoyl]-6-piperidin-1-ylpyridin-3-yl]carbamoyl]phenyl]methyl-pentan-3-ylamino]ethyl]amino]-4-oxobutanoic acid
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C47H60N8O8S
 1
1
IC50 = 192 nM
   TI
   LI
   LO
   TS
CP0580149
4-[2-[4-[[3-[[3-[[2-[3-carboxypropanoyl(methyl)amino]ethyl-pentan-3-ylamino]methyl]benzoyl]amino]-6-(2-methoxyethoxy)pyridine-2-carbonyl]amino]phenyl]ethyl]benzoic acid
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C44H53N5O9
 1
1
IC50 = 201 nM
   TI
   LI
   LO
   TS
CP0573196
4-[2-[4-[[3-[[3-[[2-[3-carboxypropanoyl(methyl)amino]ethyl-pentan-3-ylamino]methyl]benzoyl]amino]-6-morpholin-4-ylpyridine-2-carbonyl]amino]phenyl]ethyl]benzoic acid
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C45H54N6O8
 1
1
IC50 = 205 nM
   TI
   LI
   LO
   TS
CP0577077
4-[methyl-[2-[[3-[[2-[[4-[2-[4-(methylsulfonylcarbamoyl)phenyl]ethyl]phenyl]carbamoyl]-6-piperidin-1-ylpyridin-3-yl]carbamoyl]phenyl]methyl-pentan-3-ylamino]ethyl]amino]-4-oxobutanoic acid
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C47H59N7O8S
 1
1
IC50 = 237 nM
   TI
   LI
   LO
   TS
CP0970487
4-[3-(4-{[2-(3-{[(1r,4r)-4-Carboxycyclohexyl](ethyl)sulfamoyl}benzamido)-1H-indole-3-carbonyl]amino}phenyl)propyl]benzoic acid
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C41H42N4O8S
 1
1
IC50 = 257 nM
   TI
   LI
   LO
   TS
CP0572634
4-[3-[4-[[2-[[3-[[2-[carboxymethoxycarbonylsulfamoyl(methyl)amino]ethyl-pentan-3-ylamino]methyl]benzoyl]amino]-1H-indole-3-carbonyl]amino]phenyl]propyl]benzoic acid
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C44H50N6O10S
 1
1
IC50 = 267 nM
   TI
   LI
   LO
   TS
CP0573195
4-[2-[4-[[3-[[3-[[2-[3-carboxypropanoyl(methyl)amino]ethyl-pentan-3-ylamino]methyl]benzoyl]amino]-6-chloropyridine-2-carbonyl]amino]phenyl]ethyl]benzoic acid
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C41H46ClN5O7
 1
1
IC50 = 271 nM
   TI
   LI
   LO
   TS
CP0577611
4-[3-[4-[[2-[[3-[[2-[3-carboxypropanoyl(methyl)amino]ethyl-propan-2-ylamino]methyl]benzoyl]amino]-1H-indole-3-carbonyl]amino]phenyl]propyl]benzoic acid
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C43H47N5O7
 1
1
IC50 = 356 nM
   TI
   LI
   LO
   TS
CP0551939
4-[3-[4-[[2-[[3-[[2-[carboxymethylcarbamoyl(methyl)amino]ethyl-pentan-3-ylamino]methyl]benzoyl]amino]-1H-indole-3-carbonyl]amino]phenyl]propyl]benzoic acid
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C44H50N6O7
 1
1
IC50 = 369 nM
   TI
   LI
   LO
   TS
CP0569613
4-[3-[4-[[2-[[3-[[2-[[2-[(5-carbamoyl-1H-pyrrol-3-yl)sulfonylamino]acetyl]-methylamino]ethyl-pentan-3-ylamino]methyl]benzoyl]amino]-1H-indole-3-carbonyl]amino]phenyl]propyl]benzoic acid
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C48H54N8O8S
 1
1
IC50 = 401 nM
   TI
   LI
   LO
   TS
CP0969408
4-[3-(4-{[2-(3-{[(2-{[(2,5-Dioxohexahydroimidazo[4,5-d]imidazol-1(2H)-yl)acetyl](methyl)amino}ethyl)(pentan-3-yl)amino]methyl}benzamido)-1H-indole-3-carbonyl]amino}phenyl)propyl]benzoic acid
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C47H53N9O7
 1
1
IC50 = 401 nM
   TI
   LI
   LO
   TS
CP0577505
4-[[4-[[2-[[3-[[2-[3-carboxypropanoyl(methyl)amino]ethyl-pentan-3-ylamino]methyl]benzoyl]amino]-1H-indole-3-carbonyl]amino]phenyl]methyl]benzoic acid
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C43H47N5O7
 1
1
IC50 = 448 nM
   TI
   LI
   LO
   TS
CP0570247
4-[3-[4-[[2-[[3-[[2-[[4-[2-[2-[2-(2-carboxyethoxy)ethoxy]ethoxy]ethylamino]-4-oxobutanoyl]-methylamino]ethyl-pentan-3-ylamino]methyl]benzoyl]amino]-1H-indole-3-carbonyl]amino]phenyl]propyl]benzoic acid
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C54H68N6O11
 1
1
IC50 = 535 nM
   TI
   LI
   LO
   TS
CP0570244
4-[methyl-[2-[pentan-3-yl-[[3-[[3-(phenylcarbamoyl)-1H-indol-2-yl]carbamoyl]phenyl]methyl]amino]ethyl]amino]-4-oxobutanoic acid
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C35H41N5O5
 1
1
IC50 = 538 nM
   TI
   LI
   LO
   TS
CP0573198
6-[4-[[3-[[3-[[2-[3-carboxypropanoyl(methyl)amino]ethyl-pentan-3-ylamino]methyl]benzoyl]amino]-6-piperidin-1-ylpyridine-2-carbonyl]amino]phenoxy]pyridine-3-carboxylic acid
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C43H51N7O8
 1
1
IC50 = 715 nM
   TI
   LI
   LO
   TS
CP0572735
6-[[4-[[3-[[3-[[2-[3-carboxypropanoyl(methyl)amino]ethyl-pentan-3-ylamino]methyl]benzoyl]amino]-6-piperidin-1-ylpyridine-2-carbonyl]amino]phenoxy]methyl]pyridine-3-carboxylic acid
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C44H53N7O8
 1
1
IC50 = 744 nM
   TI
   LI
   LO
   TS
CP0966273
4-{3-[4-({2-[3-({3-[(3-Carboxypropanoyl)(methyl)amino]pyrrolidin-1-yl}methyl)benzamido]-1H-indole-3-carbonyl}amino)phenyl]propyl}benzoic acid hydrochloride
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C42H44ClN5O7
 1
1
IC50 = 1015 nM
   TI
   LI
   LO
   TS
CP0573197
4-[2-[4-[[3-[[3-[[2-[3-carboxypropanoyl(methyl)amino]ethyl-pentan-3-ylamino]methyl]benzoyl]amino]-6-(4-methylpiperazin-1-yl)pyridine-2-carbonyl]amino]phenyl]ethyl]benzoic acid
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C46H57N7O7
 1
1
IC50 = 1342 nM
   TI
   LI
   LO
   TS
CP0965430
4-{3-[4-({2-[3-({[1-(3-Carboxypropanoyl)pyrrolidin-3-yl](methyl)amino}methyl)benzamido]-1H-indole-3-carbonyl}amino)phenyl]propyl}benzoic acid hydrochloride
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C42H44ClN5O7
 1
1
IC50 = 2582 nM
   TI
   LI
   LO
   TS