General Information of the Compound
Compound ID
CP0573196
Compound Name
4-[2-[4-[[3-[[3-[[2-[3-carboxypropanoyl(methyl)amino]ethyl-pentan-3-ylamino]methyl]benzoyl]amino]-6-morpholin-4-ylpyridine-2-carbonyl]amino]phenyl]ethyl]benzoic acid
    Show/Hide
Structure
Formula
C45H54N6O8
Molecular Weight
806.961
Canonical SMILES
CCC(CC)N(CCN(C)C(=O)CCC(O)=O)Cc1cccc(c1)C(=O)Nc1ccc(nc1C(=O)Nc1ccc(CCc2ccc(cc2)C(O)=O)cc1)N1CCOCC1
    Show/Hide
InChI
InChI=1S/C45H54N6O8/c1-4-37(5-2)51(24-23-49(3)40(52)21-22-41(53)54)30-33-7-6-8-35(29-33)43(55)47-38-19-20-39(50-25-27-59-28-26-50)48-42(38)44(56)46-36-17-13-32(14-18-36)10-9-31-11-15-34(16-12-31)45(57)58/h6-8,11-20,29,37H,4-5,9-10,21-28,30H2,1-3H3,(H,46,56)(H,47,55)(H,53,54)(H,57,58)
    Show/Hide
InChIKey
JIQXDEBHIPISOT-UHFFFAOYSA-N
Physicochemical Property
logP
6.22
Rotatable Bonds
20
Heavy Atom Count
59
Polar Areas
181.71
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
9
Complexity
59

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 140312439
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06327, Sodium-dependent phosphate transport protein 2B
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 205 nM
   TI
   LI
   LO
   TS