METHIOTHEPIN

2-Benzyl-N-(3-chlorophenyl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine-4-amine hydrochloride

2-Benzyl-N-(3-fluorophenyl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine-4-amine hydrochloride

2-Benzyl-N-(3-methoxyphenyl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine-4-amine hydrochloride

2-Benzyl-N-phenyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine-4-amine hydrochloride

1-(phenylsulfonyl)-4-(piperazin-1-yl)-1H-indole

2-(benzenesulfonyl)-4-piperidin-4-yl-1,3-dihydroisoindole

2-(benzenesulfonyl)-4-piperazin-1-yl-1,3-dihydroisoindole

N-[6-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]hexyl]-1,2,3,4-tetrahydroacridin-9-amine

6-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]-N-benzylhexan-1-amine

N-[3-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]propyl]-1-benzylpiperidin-4-amine

2-(benzenesulfonyl)-4-(1-ethylpiperidin-4-yl)-1,3-dihydroisoindole

4-phenyl-1-(8-piperazin-1-ylquinolin-3-yl)pyrrolidin-2-one

2-(benzenesulfonyl)-4-(4-methylpiperazin-1-yl)-1,3-dihydroisoindole

1-(benzenesulfonyl)-6-piperidin-4-yl-2,3-dihydroindole

3-[3-[3-[(3,4-dichlorophenyl)sulfonylmethyl]pyrrolidin-1-yl]propyl]-6-fluoro-1,2-benzoxazole

N-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]-3-hydroxybenzenesulfonamide

4-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]-N-benzyl-N-methylbutan-1-amine

2-(benzenesulfonyl)-4-(4-propylpiperazin-1-yl)-1,3-dihydroisoindole

6-fluoro-3-[3-[3-(naphthalen-2-ylsulfonylmethyl)pyrrolidin-1-yl]propyl]-1,2-benzoxazole

2-(benzenesulfonyl)-4-(4-cyclobutylpiperazin-1-yl)-1,3-dihydroisoindole

N-[3-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]propyl]-1,2,3,4-tetrahydroacridin-9-amine

N-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]-3-methylbenzenesulfonamide

N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]naphthalene-2-sulfonamide

N-[5-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]pentyl]-1,2,3,4-tetrahydroacridin-9-amine

5-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]-N-benzylpentan-1-amine

4-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]-N-benzylbutan-1-amine

1-(benzenesulfonyl)-4-(4-methylpiperazin-1-yl)-2,3-dihydroindole

3-[3-[3-[(3-chloro-4-fluorophenyl)sulfonylmethyl]pyrrolidin-1-yl]propyl]-6-fluoro-1,2-benzoxazole

3-[3-[3-[(3,4-dimethylphenyl)sulfonylmethyl]pyrrolidin-1-yl]propyl]-6-fluoro-1,2-benzoxazole

2-(benzenesulfonyl)-4-(1-methylpiperidin-4-yl)-1,3-dihydroisoindole

N-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]-4-fluorobenzenesulfonamide

5-(3-chlorophenyl)-3-(2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)-1,3-oxazolidin-2-one

1-[8-(1,4-diazepan-1-yl)quinolin-3-yl]-4-phenylpyrrolidin-2-one

3-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]-N-benzyl-N-methylpropan-1-amine

5-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]-N-benzyl-N-methylpentan-1-amine

N-[2-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]ethyl]-1,2,3,4-tetrahydroacridin-9-amine

3-chloro-N-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]benzenesulfonamide

N-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]-3-fluorobenzenesulfonamide

2-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]-N-benzylethanamine

1-(benzenesulfonyl)-6-piperazin-1-yl-2,3-dihydroindole

N-[2-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]ethyl]-1-benzylpyrrolidin-3-amine

1-(benzenesulfonyl)-4-piperidin-4-yl-2,3-dihydroindole

6-fluoro-3-[3-[3-[[3-(trifluoromethyl)phenyl]sulfonylmethyl]pyrrolidin-1-yl]propyl]-1,2-benzoxazole

5-(2-fluorophenyl)-3-(2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)-1,3-oxazolidin-2-one

2-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]-N-benzyl-N-methylethanamine

6-fluoro-3-[3-[3-[[4-(trifluoromethyl)phenyl]sulfonylmethyl]pyrrolidin-1-yl]propyl]-1,2-benzoxazole

5-phenyl-3-(2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)-1,3-oxazolidin-2-one

3-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]-N-benzylpropan-1-amine

1-benzyl-N-(4-(4-(1-(phenylsulfonyl)-1H-indol-4-yl)piperazin-1-yl)butyl)piperidin-4-amine hydrochloride

N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]-1-benzothiophene-2-sulfonamide

3-[3-[3-[(3-chlorophenyl)sulfonylmethyl]pyrrolidin-1-yl]propyl]-6-fluoro-1,2-benzoxazole

6-fluoro-3-[3-[3-[(3-methylphenyl)sulfonylmethyl]pyrrolidin-1-yl]propyl]-1,2-benzoxazole

N-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]naphthalene-2-sulfonamide

1-(benzenesulfonyl)-5-piperazin-1-yl-2,3-dihydroindole

2-(benzenesulfonyl)-4-(1-propylpiperidin-4-yl)-1,3-dihydroisoindole

1-(benzenesulfonyl)-6-(1-ethylpiperidin-4-yl)-2,3-dihydroindole

1-(benzenesulfonyl)-6-(1-methylpiperidin-4-yl)-2,3-dihydroindole

1-(benzenesulfonyl)-6-(4-methylpiperazin-1-yl)-2,3-dihydroindole

N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]-1-benzothiophene-3-sulfonamide

2-(benzenesulfonyl)-4-(4-ethylpiperazin-1-yl)-1,3-dihydroisoindole

N-[3-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]-3-hydroxybenzenesulfonamide

1-(benzenesulfonyl)-4-(4-ethylpiperazin-1-yl)-2,3-dihydroindole

N-[2-[4-(5-fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]-3-methylbenzenesulfonamide

4-chloro-N-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]benzenesulfonamide

N-[8-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]octyl]-1,2,3,4-tetrahydroacridin-9-amine

N-[7-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]heptyl]-1,2,3,4-tetrahydroacridin-9-amine

N-[3-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]-3-methylbenzenesulfonamide

N-[2-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]ethyl]-1-benzylpiperidin-4-amine

2-(benzenesulfonyl)-4-(1-cyclobutylpiperidin-4-yl)-1,3-dihydroisoindole

3-chloro-4-fluoro-N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]benzenesulfonamide

6-fluoro-3-[3-[3-[(4-fluorophenyl)sulfonylmethyl]pyrrolidin-1-yl]propyl]-1,2-benzoxazole

3-[3-[3-[(3,4-difluorophenyl)sulfonylmethyl]pyrrolidin-1-yl]propyl]-6-fluoro-1,2-benzoxazole

1-(benzenesulfonyl)-4-(1-methylpiperidin-4-yl)-2,3-dihydroindole

N-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]naphthalene-1-sulfonamide

5-(2-chlorophenyl)-3-(2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)-1,3-oxazolidin-2-one

4-phenyl-1-(6-piperazin-1-ylpyridin-2-yl)pyrrolidin-2-one

4-phenyl-1-(2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)pyrrolidin-2-one

3-chloro-N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]benzenesulfonamide

4-phenyl-1-(4-piperazin-1-ylquinolin-7-yl)pyrrolidin-2-one

N-[3-[4-(5-fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]-3-methylbenzenesulfonamide

1-(benzenesulfonyl)-6-(4-ethylpiperazin-1-yl)-2,3-dihydroindole

N-[2-[4-(5-fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]naphthalene-2-sulfonamide

4-phenyl-1-(3-piperidin-4-ylphenyl)pyrrolidin-2-one

1-(benzenesulfonyl)-6-(1-propylpiperidin-4-yl)-2,3-dihydroindole

1-(benzenesulfonyl)-4-(4-propylpiperazin-1-yl)-2,3-dihydroindole

4-phenyl-1-(3-piperazin-1-ylphenyl)pyrrolidin-2-one

5-(2-methoxyphenyl)-3-(2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)-1,3-oxazolidin-2-one

3-(3,5-dimethoxyphenyl)spiro[1,3-thiazolidine-2,3'-1H-indole]-2',4-dione

6-fluoro-N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]-1-benzothiophene-2-sulfonamide

N-[3-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]-4-fluorobenzenesulfonamide

5-chloro-N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]-3-methyl-1-benzothiophene-2-sulfonamide

4-(2-chlorophenyl)-1-(2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)pyrrolidin-2-one

N-[4-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]naphthalene-2-sulfonamide

N-[3-[4-(5-chloro-2-methyl-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]-3-methylbenzenesulfonamide

6-chloro-N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]-1-benzothiophene-2-sulfonamide

3-chloro-N-[4-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]benzenesulfonamide

N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]-1-benzofuran-2-sulfonamide

1-(benzenesulfonyl)-4-piperazin-1-yl-2,3-dihydroindole

3-chloro-N-[3-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]benzenesulfonamide

1-(benzenesulfonyl)-6-(4-propylpiperazin-1-yl)-2,3-dihydroindole

1-(benzenesulfonyl)-5-(1-methylpiperidin-4-yl)-2,3-dihydroindole

1-(benzenesulfonyl)-5-(4-ethylpiperazin-1-yl)-2,3-dihydroindole

N-[4-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]naphthalene-1-sulfonamide

N-[2-[4-(5-chloro-2-methyl-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]-3-methylbenzenesulfonamide

4-phenyl-1-(1,2,3,4-tetrahydroisoquinolin-7-yl)pyrrolidin-2-one

5-(2-chlorophenyl)-3-(3-piperazin-1-ylphenyl)-1,3-oxazolidin-2-one

5-(2-chlorophenyl)-3-(1,2,3,4-tetrahydroisoquinolin-7-yl)-1,3-oxazolidin-2-one

4-chloro-N-[4-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]benzenesulfonamide

6-fluoro-3-[3-[3-[(3-fluorophenyl)sulfonylmethyl]pyrrolidin-1-yl]propyl]-1,2-benzoxazole

6-chloro-N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]naphthalene-2-sulfonamide

1-(benzenesulfonyl)-4-(1-ethylpiperidin-4-yl)-2,3-dihydroindole

1-(benzenesulfonyl)-5-piperidin-4-yl-2,3-dihydroindole

N-[2-[4-(5-chloro-2-methyl-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]naphthalene-2-sulfonamide

4-chloro-N-[3-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]benzenesulfonamide

1-(benzenesulfonyl)-6-(4-cyclobutylpiperazin-1-yl)-2,3-dihydroindole

N-[4-[4-(5-fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]naphthalene-2-sulfonamide

N-[3-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]-3-fluorobenzenesulfonamide

4-[1-(2,3-dichlorophenoxy)propyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine

N-[4-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]-3-methylbenzenesulfonamide

N-[3-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]naphthalene-2-sulfonamide

5-(2-chlorophenyl)-3-(3-piperidin-4-yloxyphenyl)-1,3-oxazolidin-2-one

N-[4-[4-(5-fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]-3-methylbenzenesulfonamide

N-[4-[4-(5-chloro-2-methyl-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]naphthalene-2-sulfonamide

N-[3-[4-(5-fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]naphthalene-2-sulfonamide

2-(benzenesulfonyl)-5-piperidin-4-yl-1,3-dihydroisoindole

1-(benzenesulfonyl)-4-(4-cyclobutylpiperazin-1-yl)-2,3-dihydroindole

4-[1-(2,3-dichlorophenoxy)ethyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine

N-[3-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]naphthalene-1-sulfonamide

2-(benzenesulfonyl)-5-piperazin-1-yl-1,3-dihydroisoindole

N-[4-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]-4-fluorobenzenesulfonamide

4-[1-(2,3-dichlorophenoxy)butyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine

N-[4-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]-3-fluorobenzenesulfonamide

5-(2-chlorophenyl)-3-(1,2,3,4-tetrahydroisoquinolin-6-yl)-1,3-oxazolidin-2-one

N-[4-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]-3-hydroxybenzenesulfonamide

N-[3-[4-(5-chloro-2-methyl-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]naphthalene-2-sulfonamide

4-[1-(2,5-dichlorophenoxy)ethyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine

N-[4-[4-(5-chloro-2-methyl-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]-3-methylbenzenesulfonamide

4-[1-(2,5-dichlorophenoxy)butyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine

4-[1-(3,5-dichlorophenoxy)ethyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine

4-[1-(2,5-dichlorophenoxy)pentyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine

1-(benzenesulfonyl)-5-(4-methylpiperazin-1-yl)-2,3-dihydroindole

4-[1-(3,5-dichlorophenoxy)propyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine

4-[1-(2,3-dichlorophenoxy)pentyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine

4-[1-(2,5-dichlorophenoxy)propyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine

4-[1-(3,5-dichlorophenoxy)butyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine

1-(benzenesulfonyl)-6-(1-cyclobutylpiperidin-4-yl)-2,3-dihydroindole

2-(benzenesulfonyl)-5-(1-methylpiperidin-4-yl)-1,3-dihydroisoindole

4-[1-(3,4-dichlorophenoxy)ethyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine

4-[3-(2,3-dichlorophenoxy)propyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine

7-[3-(2-chlorophenyl)pyrrolidin-1-yl]-2,3,4,5-tetrahydro-1H-3-benzazepine

4-[1-(3,4-dichlorophenoxy)propyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine

4-[1-(3,5-dichlorophenoxy)pentyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine

4-[3-(3,4-dichlorophenoxy)propyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine

1-(benzenesulfonyl)-4-(1-propylpiperidin-4-yl)-2,3-dihydroindole

4-phenyl-1-(2,3,4,5-tetrahydro-1H-2-benzazepin-7-yl)pyrrolidin-2-one

4-[3-(2,5-dichlorophenoxy)propyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine

4-[1-(2-chlorophenoxy)ethyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine

5-(2-chlorophenyl)-3-(4-piperazin-1-ylphenyl)-1,3-oxazolidin-2-one

4-phenyl-1-(5-piperazin-1-ylpyridin-3-yl)pyrrolidin-2-one

1-(8-piperazin-1-ylquinolin-3-yl)pyrrolidin-2-one

4-(4-methylpiperazin-1-yl)-6-(1-phenoxypropyl)-1,3,5-triazin-2-amine

3-phenylspiro[1,3-thiazolidine-2,3'-1H-indole]-2',4-dione

1-[2-(4-methylpiperazin-1-yl)-1,3-thiazol-5-yl]-4-phenylpyrrolidin-2-one