Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(phenylsulfonyl)-4-(piperazin-1-yl)-1H-indole
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 PubChem ID
CID: 10154392
SID: 15147463
Canonical SMILES
O=S(=O)(c1ccccc1)n1ccc2c(cccc12)N1CCNCC1
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Compound Formula C18H19N3O2S
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 0.3 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
Ki = 0.3 nM
   TI
   LI
   LO
   TS
2
Ki = 1 nM
   TI
   LI
   LO
   TS
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 0.3162 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1 nM