| Compound ID |
Compound Name |
Compound Formula |
|
CP0544324
|
6-[3-(trifluoromethoxy)phenyl]sulfanyl-2H-[1,2,4]triazolo[4,3-b]pyridazin-3-one
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|
C12H7F3N4O2S
|
1
|
| 1 |
EC50 = 34 nM
|
|
|
|
CP0579669
|
6-(4-methylphenyl)sulfanyl-2H-[1,2,4]triazolo[4,3-b]pyridazin-3-one
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|
C12H10N4OS
|
1
|
| 1 |
EC50 = 86 nM
|
|
|
|
CP0260378
|
6-(3-chlorophenyl)sulfanyl-2H-[1,2,4]triazolo[4,3-b]pyridazin-3-one
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|
C11H7ClN4OS
|
1
|
| 1 |
EC50 = 88 nM
|
|
|
|
CP0526878
|
1-[2-(6-chloro-7-cyclopropylthieno[3,2-d]pyrimidin-4-yl)sulfanylacetyl]-3-methylimidazolidin-4-one
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|
C15H15ClN4O2S2
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0549278
|
6-(3,4-dichlorophenyl)sulfanyl-2H-[1,2,4]triazolo[4,3-b]pyridazin-3-one
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|
C11H6Cl2N4OS
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0546179
|
6-(3,4-dimethylphenyl)sulfanyl-2H-[1,2,4]triazolo[4,3-b]pyridazin-3-one
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|
C13H12N4OS
|
1
|
| 1 |
EC50 = 130 nM
|
|
|
|
CP0527952
|
6-(3-methoxyphenyl)sulfanyl-2H-[1,2,4]triazolo[4,3-b]pyridazin-3-one
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|
C12H10N4O2S
|
1
|
| 1 |
EC50 = 140 nM
|
|
|
|
CP0488475
|
6-(3-ethoxyphenyl)sulfanyl-2H-[1,2,4]triazolo[4,3-b]pyridazin-3-one
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|
C13H12N4O2S
|
1
|
| 1 |
EC50 = 150 nM
|
|
|
|
CP0549276
|
6-(2,3-dichlorophenyl)sulfanyl-2H-[1,2,4]triazolo[4,3-b]pyridazin-3-one
Show/Hide
|
C11H6Cl2N4OS
|
1
|
| 1 |
EC50 = 150 nM
|
|
|
|
CP0535031
|
3-methyl-1-[2-[6-methyl-5-(trifluoromethyl)thieno[2,3-d]pyrimidin-4-yl]sulfanylacetyl]imidazolidin-4-one
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|
C14H13F3N4O2S2
|
1
|
| 1 |
EC50 = 170 nM
|
|
|
|
CP0552676
|
6-[3-(trifluoromethyl)phenyl]sulfanyl-2H-[1,2,4]triazolo[4,3-b]pyridazin-3-one
Show/Hide
|
C12H7F3N4OS
|
1
|
| 1 |
EC50 = 190 nM
|
|
|
|
CP0558706
|
3-methyl-1-[2-[5-methyl-6-(trifluoromethyl)thieno[2,3-d]pyrimidin-4-yl]sulfanylacetyl]imidazolidin-4-one
Show/Hide
|
C14H13F3N4O2S2
|
1
|
| 1 |
EC50 = 210 nM
|
|
|
|
CP0137276
|
3-methyl-1-[2-[5-methyl-6-(trifluoromethyl)furo[2,3-d]pyrimidin-4-yl]sulfanylacetyl]imidazolidin-4-one
Show/Hide
|
C14H13F3N4O3S
|
1
|
| 1 |
EC50 = 220 nM
|
|
|
|
CP0549274
|
6-(3-methylphenyl)sulfanyl-2H-[1,2,4]triazolo[4,3-b]pyridazin-3-one
Show/Hide
|
C12H10N4OS
|
1
|
| 1 |
EC50 = 240 nM
|
|
|
|
CP0579449
|
6-(3-fluorophenyl)sulfanyl-2H-[1,2,4]triazolo[4,3-b]pyridazin-3-one
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|
C11H7FN4OS
|
1
|
| 1 |
EC50 = 260 nM
|
|
|
|
CP0579670
|
6-(3-propan-2-yloxyphenyl)sulfanyl-2H-[1,2,4]triazolo[4,3-b]pyridazin-3-one
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|
C14H14N4O2S
|
1
|
| 1 |
EC50 = 260 nM
|
|
|
|
CP0343988
|
6-[4-(trifluoromethyl)phenyl]sulfanyl-2H-[1,2,4]triazolo[4,3-b]pyridazin-3-one
Show/Hide
|
C12H7F3N4OS
|
1
|
| 1 |
EC50 = 300 nM
|
|
|
|
CP0573570
|
6-(2,4-dimethylphenyl)sulfanyl-2H-[1,2,4]triazolo[4,3-b]pyridazin-3-one
Show/Hide
|
C13H12N4OS
|
1
|
| 1 |
EC50 = 300 nM
|
|
|
|
CP0573573
|
6-(2-methylphenyl)sulfanyl-2H-[1,2,4]triazolo[4,3-b]pyridazin-3-one
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|
C12H10N4OS
|
1
|
| 1 |
EC50 = 300 nM
|
|
|
|
CP0527951
|
6-(4-chlorophenyl)sulfanyl-2H-[1,2,4]triazolo[4,3-b]pyridazin-3-one
Show/Hide
|
C11H7ClN4OS
|
1
|
| 1 |
EC50 = 310 nM
|
|
|
|
CP0549277
|
6-(2,4-dichlorophenyl)sulfanyl-2H-[1,2,4]triazolo[4,3-b]pyridazin-3-one
Show/Hide
|
C11H6Cl2N4OS
|
1
|
| 1 |
EC50 = 380 nM
|
|
|
|
CP0575707
|
6-(3-methylsulfanylphenyl)sulfanyl-2H-[1,2,4]triazolo[4,3-b]pyridazin-3-one
Show/Hide
|
C12H10N4OS2
|
1
|
| 1 |
EC50 = 380 nM
|
|
|
|
CP0549275
|
6-(4-fluorophenyl)sulfanyl-2H-[1,2,4]triazolo[4,3-b]pyridazin-3-one
Show/Hide
|
C11H7FN4OS
|
1
|
| 1 |
EC50 = 540 nM
|
|
|
|
CP0546177
|
6-(2-chlorophenyl)sulfanyl-2H-[1,2,4]triazolo[4,3-b]pyridazin-3-one
Show/Hide
|
C11H7ClN4OS
|
1
|
| 1 |
EC50 = 720 nM
|
|
|
|
CP0573569
|
6-[2-(trifluoromethyl)phenyl]sulfanyl-2H-[1,2,4]triazolo[4,3-b]pyridazin-3-one
Show/Hide
|
C12H7F3N4OS
|
1
|
| 1 |
EC50 = 930 nM
|
|
|
|
CP0552675
|
6-(2-fluorophenyl)sulfanyl-2H-[1,2,4]triazolo[4,3-b]pyridazin-3-one
Show/Hide
|
C11H7FN4OS
|
1
|
| 1 |
EC50 = 1100 nM
|
|
|
|
CP0552678
|
6-(3,4-difluorophenyl)sulfanyl-2H-[1,2,4]triazolo[4,3-b]pyridazin-3-one
Show/Hide
|
C11H6F2N4OS
|
1
|
| 1 |
EC50 = 1100 nM
|
|
|
|
CP0526879
|
1-[2-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)sulfanylacetyl]-3-methylimidazolidin-4-one
Show/Hide
|
C14H16N4O2S2
|
1
|
| 1 |
EC50 = 1300 nM
|
|
|
|
CP0572046
|
6-(6-methylpyridin-2-yl)sulfanyl-2H-[1,2,4]triazolo[4,3-b]pyridazin-3-one
Show/Hide
|
C11H9N5OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0573571
|
6-[6-(trifluoromethyl)pyridin-2-yl]sulfanyl-2H-[1,2,4]triazolo[4,3-b]pyridazin-3-one
Show/Hide
|
C11H6F3N5OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0343987
|
(4Z)-2-(3,4-dimethylphenyl)-4-[(5-methylfuran-2-yl)methylidene]-1,3-oxazol-5-one
Show/Hide
|
C17H15NO3
|
1
|
| 1 |
EC50 > 10 nM
|
|
|
|
CP0543016
|
(4E)-2-(3,4-dimethylphenyl)-4-[(5-methylfuran-2-yl)methylidene]-1,3-oxazol-5-one
Show/Hide
|
C17H15NO3
|
1
|
| 1 |
EC50 > 10 nM
|
|
|
|
CP0529070
|
[7-[(4-bromophenyl)methyl]-1,3-dioxo-5,6,8,8a-tetrahydroimidazo[1,5-a]pyrazin-2-yl] 4-(4-methoxyphenyl)piperazine-1-carboxylate
Show/Hide
|
C25H28BrN5O5
|
1
|
| 1 |
IC50 = 677 nM
|
|
|
|
CP0408412
|
[1,3-dioxo-7-[(6-phenoxypyridin-3-yl)methyl]-5,6,8,8a-tetrahydroimidazo[1,5-a]pyrazin-2-yl] 2,3-dihydro-1,4-benzoxazine-4-carboxylate
Show/Hide
|
C27H25N5O6
|
1
|
| 1 |
IC50 = 1506 nM
|
|
|
|
CP0043620
|
1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
Show/Hide
|
C8H10N4O2
|
1
|
| 1 |
Kd = 85000 nM
|
|
|
