Brief Information of the Compound and Protein
Compound Name
3-methyl-1-[2-[5-methyl-6-(trifluoromethyl)thieno[2,3-d]pyrimidin-4-yl]sulfanylacetyl]imidazolidin-4-one
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PubChem ID
CID: 156010785
Canonical SMILES
CN1CN(CC1=O)C(=O)CSc1ncnc2sc(c(C)c12)C(F)(F)F
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Compound Formula C14H13F3N4O2S2
Compound Structure
Protein Name
Palmitoleoyl-protein carboxylesterase NOTUM
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q6P988
Gene Name
NOTUM
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
EC50 = 210 nM
   TI
   LI
   LO
   TS
CL000107 HEK293S Homo sapiens (Human)  1
1
IC50 = 1.6 nM
   TI
   LI
   LO
   TS