| Compound ID |
Compound Name |
Compound Formula |
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CP0475491
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(2S)-2-acetamido-N-[(2S)-1-[[(1R)-1-[5-[(1R)-1-[(2-amino-2-methylpropanoyl)amino]-2-(1H-indol-3-yl)ethyl]-4-[(4-methoxyphenyl)methyl]-1,2,4-triazol-3-yl]-2-(1H-indol-3-yl)ethyl]amino]-4-methyl-1-oxopentan-2-yl]-4-methylpentanamide
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C48H62N10O5
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2
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| 1 |
EC50 = 0.8 nM
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| 2 |
Ki = 30 nM
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CP0280449
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Ghrelin
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C149H249N47O42
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2
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| 1 |
EC50 = 1.51 nM
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| 2 |
Ki = 1.28 nM
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CP0440551
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2-[[(2S,3S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S,3R)-2-[[(2S)-2-aminohexanoyl]amino]-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-methylpentanoyl]amino]acetic acid
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C76H119N21O17
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6
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| 1 |
EC50 = 2.5 nM
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| 2 |
EC50 = 18 nM
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| 3 |
EC50 = 76.4 nM
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| 4 |
Kd = 34.67 nM
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| 5 |
Kd = 89.13 nM
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| 6 |
Ki = 3.66 nM
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CP0544918
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(2S)-N-[(1R)-1-[5-[(1R)-1-acetamido-2-(1H-indol-3-yl)ethyl]-4-[(4-methoxyphenyl)methyl]-1,2,4-triazol-3-yl]-2-(1H-indol-3-yl)ethyl]-2,6-diaminohexanamide
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C38H45N9O3
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2
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| 1 |
EC50 = 4 nM
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| 2 |
Ki = 2.5 nM
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CP0848185
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N-((R)-1-(5-((R)-1-((S)-2-((S)-2-acetamido-4-methylpentanamido)-4-methylpentanamido)-2-(1H-indol-3-yl)ethyl)-4-(4-methoxybenzyl)-4H-1,2,4-triazol-3-yl)-2-(1H-indol-3-yl)ethyl)piperidine-4-carboxamide
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C50H64N10O5
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2
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| 1 |
EC50 = 4.4 nM
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| 2 |
Ki = 2 nM
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CP0158770
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(2S)-2,6-diamino-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-naphthalen-1-yl-1-oxopropan-2-yl]hexanamide
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C51H67N9O6
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2
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| 1 |
EC50 = 5.5 nM
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| 2 |
Ki = 3.7 nM
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CP0444785
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(2S)-2,6-diamino-N-[(1R)-1-[5-[(1R)-1-formamido-2-(1H-indol-3-yl)ethyl]-4-[(4-methoxyphenyl)methyl]-1,2,4-triazol-3-yl]-2-(1H-indol-3-yl)ethyl]hexanamide
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C37H43N9O3
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2
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| 1 |
EC50 = 10 nM
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| 2 |
Ki = 8 nM
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CP0169048
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(2S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(1R,4S,7S,10R,13R,16R,19S,24R,27S,30S,33S,36S,39R,46S,49S,52S,55S)-30-(4-aminobutyl)-19-[[(2R)-2-[[(2R)-2-[[2-[[(2S,3S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S,3R)-2-[[(2S)-2-aminohexanoyl]amino]-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-carbamimidamidopentanoyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]pyrrolidine-2-carbonyl]amino]-3-methylpentanoyl]amino]acetyl]amino]propanoyl]amino]-3-hydroxypropanoyl]amino]-16,27,33,36,52-pentakis(3-carbamimidamidopropyl)-4-(2-carboxyethyl)-10,13-bis(carboxymethyl)-46,49-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-55-(2-methylpropyl)-3,6,9,12,15,18,25,28,31,34,37,44,47,50,53,56-hexadecaoxo-21,22,41,42-tetrathia-2,5,8,11,14,17,26,29,32,35,38,45,48,51,54,57-hexadecazabicyclo[22.19.14]heptapentacontane-39-carbonyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-5-oxopentanoyl]amino]pentanedioic acid
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C190H314N64O58S4
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6
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| 1 |
EC50 = 16.6 nM
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| 2 |
EC50 = 22.8 nM
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| 3 |
EC50 = 27.7 nM
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| 4 |
Kd = 1.479 nM
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| 5 |
Kd = 10.23 nM
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| 6 |
Ki = 1.26 nM
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CP0510758
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methyl 2-[[(1R)-1-[5-[(1R)-1-[[(2S)-2,6-diaminohexanoyl]amino]-2-(1H-indol-3-yl)ethyl]-4-[(4-methoxyphenyl)methyl]-1,2,4-triazol-3-yl]-2-(1H-indol-3-yl)ethyl]carbamoyl]-4-methylpentanoate
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C44H55N9O5
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2
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| 1 |
EC50 = 20 nM
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| 2 |
Ki = 17 nM
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CP0358131
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(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S,3R)-2-[[(2S)-2-aminohexanoyl]amino]-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carboxamide
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C68H106N20O14
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2
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| 1 |
EC50 = 46 nM
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| 2 |
Ki = 2.7 nM
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CP0302842
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(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S,3R)-2-[[(2S)-2-aminohexanoyl]amino]-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S,3S)-1-[(2-amino-2-oxoethyl)amino]-3-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
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C76H120N22O16
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2
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| 1 |
EC50 = 48 nM
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| 2 |
Ki = 3.05 nM
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CP0904713
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(S)-N-((R)-1-(5-((R)-1-((S)-2-((S)-2-acetamido-4-methylpentanamido)-4-methylpentanamido)-2-(1H-indol-3-yl)ethyl)-4-(4-methoxybenzyl)-4H-1,2,4-triazol-3-yl)-2-(1H-indol-3-yl)ethyl)morpholine-2-carboxamide
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C49H62N10O6
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2
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| 1 |
EC50 = 60 nM
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| 2 |
Ki = 50 nM
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CP0444784
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(2S)-N-[(1R)-1-[5-[(1R)-1-[[(2S)-2-[[(2S)-2-acetamido-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-2-(1H-indol-3-yl)ethyl]-4-[(4-methoxyphenyl)methyl]-1,2,4-triazol-3-yl]-2-(1H-indol-3-yl)ethyl]-2,6-diaminohexanamide
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C50H67N11O5
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2
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| 1 |
EC50 = 70 nM
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| 2 |
Ki = 110 nM
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CP0428595
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(2S)-2-acetamido-N-[(2S)-1-[[(1R)-1-[5-[(1R)-1-[(2-hydroxy-2-methylpropanoyl)amino]-2-(1H-indol-3-yl)ethyl]-4-[(4-methoxyphenyl)methyl]-1,2,4-triazol-3-yl]-2-(1H-indol-3-yl)ethyl]amino]-4-methyl-1-oxopentan-2-yl]-4-methylpentanamide
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C48H61N9O6
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2
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| 1 |
EC50 = 74 nM
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| 2 |
Ki = 3 nM
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CP0419821
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methyl (2S)-2-[[2-[[(1R)-1-[5-[(1R)-1-[[(2S)-2,6-diaminohexanoyl]amino]-2-(1H-indol-3-yl)ethyl]-4-[(4-methoxyphenyl)methyl]-1,2,4-triazol-3-yl]-2-(1H-indol-3-yl)ethyl]carbamoyl]-4-methylpentanoyl]amino]-4-methylpentanoate
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C50H66N10O6
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2
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| 1 |
EC50 = 82 nM
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| 2 |
Ki = 220 nM
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CP0422017
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(2S)-2-[[(2R)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-1-[(2R)-2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]pentanediamide
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C79H109N19O12
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2
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| 1 |
EC50 = 98.7 nM
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| 2 |
Ki = 76.7 nM
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CP0379087
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(2S)-2,6-diamino-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]hexanamide
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C49H66N10O6
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2
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| 1 |
EC50 = 100 nM
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| 2 |
Ki = 255 nM
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CP0535785
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(2S)-1-[(2S,3R)-2-[[(2S)-2-aminohexanoyl]amino]-3-hydroxybutanoyl]-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-2-oxoethyl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]pyrrolidine-2-carboxamide
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C57H87N15O12
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2
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| 1 |
EC50 = 134 nM
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| 2 |
Ki = 3.4 nM
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CP0447866
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N-[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]-N'-[(1R)-1-[5-[(1R)-1-[[(2S)-2,6-diaminohexanoyl]amino]-2-(1H-indol-3-yl)ethyl]-4-[(4-methoxyphenyl)methyl]-1,2,4-triazol-3-yl]-2-(1H-indol-3-yl)ethyl]-2-(2-methylpropyl)propanediamide
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C49H65N11O5
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2
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| 1 |
EC50 = 170 nM
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| 2 |
Ki = 210 nM
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CP0435142
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(2S)-1-[(2S,3R)-2-[[(2S)-2-aminohexanoyl]amino]-3-hydroxybutanoyl]-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-amino-3-methyl-1-oxobutan-2-yl]amino]-2-oxoethyl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]pyrrolidine-2-carboxamide
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C48H71N13O9
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2
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| 1 |
EC50 = 368 nM
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| 2 |
Ki = 6.45 nM
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CP0360853
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(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-1-[(2S,3R)-2-[[(2S)-2-aminohexanoyl]amino]-3-hydroxybutanoyl]pyrrolidine-2-carboxamide
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C41H59N11O7
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2
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| 1 |
EC50 = 6633 nM
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| 2 |
Ki = 55 nM
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CP0504852
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(2S)-2-acetamido-N-[(2S)-1-[[(1R)-1-[5-[(1R)-1-[(2-hydroxyacetyl)amino]-2-(1H-indol-3-yl)ethyl]-4-[(4-methoxyphenyl)methyl]-1,2,4-triazol-3-yl]-2-(1H-indol-3-yl)ethyl]amino]-4-methyl-1-oxopentan-2-yl]-4-methylpentanamide
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C46H57N9O6
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1
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| 1 |
Ki = 3 nM
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