Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S)-2,6-diamino-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]hexanamide
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 PubChem ID
CID: 44576247
Canonical SMILES
CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)CCCCN)C(N)=O
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Compound Formula C49H66N10O6
Compound Structure
Protein Name
 Protein Info 
Growth hormone secretagogue receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
GRP-related receptor
Uniprot ID
Q92847
Gene Name
GHSR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  14
1
EC50 = 45.6 nM
   TI
   LI
   LO
   TS
2
IC50 = 2.6 nM
   TI
   LI
   LO
   TS
3
IC50 = 13 nM
   TI
   LI
   LO
   TS
4
IC50 = 19 nM
   TI
   LI
   LO
   TS
5
IC50 = 21 nM
   TI
   LI
   LO
   TS
6
IC50 = 27 nM
   TI
   LI
   LO
   TS
7
IC50 = 29 nM
   TI
   LI
   LO
   TS
8
IC50 = 32 nM
   TI
   LI
   LO
   TS
9
IC50 = 36 nM
   TI
   LI
   LO
   TS
10
IC50 = 43 nM
   TI
   LI
   LO
   TS
11
IC50 = 60 nM
   TI
   LI
   LO
   TS
12
IC50 = 61 nM
   TI
   LI
   LO
   TS
13
IC50 = 83 nM
   TI
   LI
   LO
   TS
14
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 100 nM
   TI
   LI
   LO
   TS
2
Ki = 255 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 255 nM