| Compound ID |
Compound Name |
Compound Formula |
|
CP0001862
|
N-[5-[8-[4-[[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]methyl]triazol-1-yl]octyl-methylamino]pentyl]-2-[5-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridin-3-yl]oxyacetamide
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|
C49H65N9O5S
|
3
|
| 1 |
IC50 = 110 nM
|
|
|
| 2 |
Ki = 1000 nM
|
|
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| 3 |
Ki = 1300 nM
|
|
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CP0011589
|
N-[4-[2-[(5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)-propylamino]ethyl]phenyl]-3-[1-[8-[methyl-[5-[[2-[5-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridin-3-yl]oxyacetyl]amino]pentyl]amino]octyl]triazol-4-yl]propanamide
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|
C53H71N9O4S
|
3
|
| 1 |
IC50 = 170 nM
|
|
|
| 2 |
Ki = 1100 nM
|
|
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| 3 |
Ki = 2300 nM
|
|
|
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CP0007431
|
N-[5-[8-[4-[[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]methyl]triazol-1-yl]octyl-methylamino]pentyl]-2-[3-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]phenoxy]acetamide
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|
C50H66N8O5S
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0007147
|
N-[5-[10-[4-[[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]methyl]triazol-1-yl]decyl-methylamino]pentyl]-2-[3-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]phenoxy]acetamide
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|
C52H70N8O5S
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0013424
|
N-[4-[2-[(5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)-propylamino]ethyl]phenyl]-3-[1-[10-[methyl-[5-[[2-[5-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridin-3-yl]oxyacetyl]amino]pentyl]amino]decyl]triazol-4-yl]propanamide
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|
C55H75N9O4S
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0006108
|
N-[5-[10-[4-[[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]methyl]triazol-1-yl]decyl-methylamino]pentyl]-2-[5-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridin-3-yl]oxyacetamide
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|
C51H69N9O5S
|
1
|
| 1 |
IC50 = 450 nM
|
|
|
|
CP0012892
|
N-[2-[2-[2-[2-[2-[2-[4-[[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]-2-[5-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridin-3-yl]oxyacetamide
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|
C47H60N8O10S
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
|
CP0014446
|
N-[2-[2-[2-[2-[4-[[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethyl]-2-[5-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridin-3-yl]oxyacetamide
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|
C43H52N8O8S
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0012430
|
N-[4-[2-[(5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)-propylamino]ethyl]phenyl]-3-[1-[6-[[2-[5-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridin-3-yl]oxyacetyl]amino]hexyl]triazol-4-yl]propanamide
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|
C45H54N8O4S
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0006109
|
N-[5-[8-azidooctyl(methyl)amino]pentyl]-2-[5-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridin-3-yl]oxyacetamide
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|
C27H39N7O2S
|
3
|
| 1 |
IC50 = 2600 nM
|
|
|
| 2 |
Ki = 5700 nM
|
|
|
| 3 |
Ki = 5800 nM
|
|
|
|
CP0502156
|
3-Fluoro-5-cyano-1-(2-methylthiazol-4-ylethynyl)benzene
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|
C13H7FN2S
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0382061
|
1-Fluoro-3-(pyridin-3-yl)-5-(2-methylthiazol-4ylethynyl)benzene
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|
C17H11FN2S
|
1
|
| 1 |
Ki = 2.7 nM
|
|
|
|
CP0437591
|
2-Phenyl-5-(2-methylthiazol-4ylethynyl)pyridine
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|
C17H12N2S
|
1
|
| 1 |
Ki = 5.49 nM
|
|
|
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CP0374317
|
2-(Pyridin-3-yl)-5-(2-methylthiazol-4ylethynyl)pyridine
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|
C16H11N3S
|
1
|
| 1 |
Ki = 5.65 nM
|
|
|
|
CP0374326
|
3-Cyano-4-phenyl-N-(6-methylpyridin-2-yl)-benzamide
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|
C20H15N3O
|
1
|
| 1 |
Ki = 9.8 nM
|
|
|
|
CP0400207
|
3-Phenyl-1-(2-methylthiazol-4-ylethynyl)benzene
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|
C18H13NS
|
1
|
| 1 |
Ki = 10.76 nM
|
|
|
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CP0374365
|
1-(Pyridin-3-yl)-2-fluoro-4-(2-methylthiazol-4ylethynyl)benzene
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|
C17H11FN2S
|
1
|
| 1 |
Ki = 11.4 nM
|
|
|
|
CP0191235
|
2-Methyl-6-(phenylethynyl)pyridine
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|
C14H11N
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0374320
|
3-Cyano-4'-(3-fluorophenyl)-N-(6-methylpyridin-2-yl)-benzamide
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|
C20H14FN3O
|
1
|
| 1 |
Ki = 22 nM
|
|
|
|
CP0382059
|
4-(3'-Chloro-phenyl)-N-(6-methylpyridin-2-yl)-benzamide
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|
C19H15ClN2O
|
1
|
| 1 |
Ki = 3330 nM
|
|
|
|
CP0453860
|
4-Phenyl-N-(6-methylpyridin-2-yl)-benzamide
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|
C19H16N2O
|
1
|
| 1 |
Ki = 7000 nM
|
|
|
|
CP0374322
|
4-Phenoxy-N-(6-methylpyridin-2-yl)-benzamide
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|
C19H16N2O2
|
1
|
| 1 |
Ki = 7290 nM
|
|
|
|
CP0450467
|
3,5-Difluoro-N-(6-methylpyridin-2-yl)-benzamide
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|
C13H10F2N2O
|
1
|
| 1 |
Ki = 7580 nM
|
|
|
|
CP0374323
|
4-Bromo-N-(6-methylpyridin-2-yl)-benzamide
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|
C13H11BrN2O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0374366
|
4-Cyano-N-(6-methylpyridin-2-yl)-benzamide
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|
C14H11N3O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0377705
|
3,4-Difluoro-N-(6-methylpyridin-2-yl)-benzamide
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|
C13H10F2N2O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0377706
|
4-(3'-Cyano-phenyl)-N-(6-methylpyridin-2-yl)-benzamide
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|
C20H15N3O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0471957
|
4-(Benzyloxy)-N-(6-methylpyridin-2-yl)-benzamide
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|
C20H16N2O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
