Brief Information of the Compound and Protein
Compound Name
N-[5-[8-azidooctyl(methyl)amino]pentyl]-2-[5-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridin-3-yl]oxyacetamide
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PubChem ID
CID: 145985513
Canonical SMILES
CN(CCCCCCCCN=[N+]=[N-])CCCCCNC(=O)COc1cncc(c1)C#Cc1csc(C)n1
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Compound Formula C27H39N7O2S
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  3
1
IC50 = 2600 nM
   TI
   LI
   LO
   TS
2
Ki = 5700 nM
   TI
   LI
   LO
   TS
3
Ki = 5800 nM
   TI
   LI
   LO
   TS