Brief Information of the Cell Line and Protein
Cell Line ID: CL000023 , BTI-Tn-5B1-4
Synonyms
BTI-TN-5B1-4
BTI-TN5B1-4
BTI-Tn5B14
BTI-Tn 5B1-4
Tn-5B1-4
Tn 5B1-4
Tn5 B1-4
Tn5B1-4
TN5B14
TnH5
High Five
High 5
High-5
High5
Hi-five
Hi-5
Hi5
Tn-5
Category Spontaneously immortalized cell line
Organism
Trichoplusia ni (Cabbage looper)
Cellosaurus ID
CVCL_C190
Protein ID: PT00994 , Histone deacetylase 4
Gene Name HDAC4
Organism Homo sapiens, Human
Protein Classification Epigenetic regulator
Uniprot ID P56524
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000023  Protein ID: PT00994
 
Compound ID Compound Name Compound Formula
CP0497727
5-cyclopropyl-2-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)-N-(6,6,6-trifluoro-5-oxohexyl)-1,3-thiazole-4-carboxamide
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C20H22F3N3O2S2
 1
1
IC50 = 23.42 nM
   TI
   LI
   LO
   TS
CP0424976
5-cyclopropyl-2-(1,3-thiazol-2-yl)-N-(6,6,6-trifluoro-5-oxohexyl)-1,3-thiazole-4-carboxamide
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C16H16F3N3O2S2
 1
1
IC50 = 31.54 nM
   TI
   LI
   LO
   TS
CP0424978
5-cyclopropyl-2-(5-methyl-1,3-thiazol-2-yl)-N-(6,6,6-trifluoro-5-oxohexyl)-1,3-thiazole-4-carboxamide
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C17H18F3N3O2S2
 1
1
IC50 = 32.05 nM
   TI
   LI
   LO
   TS
CP0388780
5-benzyl-2-(1,3-thiazol-2-yl)-N-(6,6,6-trifluoro-5-oxohexyl)-1,3-thiazole-4-carboxamide
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C20H18F3N3O2S2
 1
1
IC50 = 68.15 nM
   TI
   LI
   LO
   TS
CP0483501
5-(2-methylpropyl)-2-(1,3-thiazol-2-yl)-N-(6,6,6-trifluoro-5-oxohexyl)-1,3-thiazole-4-carboxamide
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C17H20F3N3O2S2
 1
1
IC50 = 120.03 nM
   TI
   LI
   LO
   TS
CP0406684
5-cyclopropyl-2-(1,3-thiazol-2-yl)-N-(7,7,7-trifluoro-6-oxoheptyl)-1,3-thiazole-4-carboxamide
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C17H18F3N3O2S2
 1
1
IC50 = 132.88 nM
   TI
   LI
   LO
   TS
CP0085031
5-cyclopropyl-N-[5-(hydroxyamino)-5-oxopentyl]-2-(1,3-thiazol-2-yl)-1,3-thiazole-4-carboxamide
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C15H18N4O3S2
 1
1
IC50 = 157.79 nM
   TI
   LI
   LO
   TS
CP0209171
N-[5-(hydroxyamino)-5-oxopentyl]-5-(2-methylpropyl)-2-(1,3-thiazol-2-yl)-1,3-thiazole-4-carboxamide
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C16H22N4O3S2
 1
1
IC50 = 184.67 nM
   TI
   LI
   LO
   TS
CP0003832
N'-hydroxy-N-phenyloctanediamide
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C14H20N2O3
 1
1
IC50 = 353.78 nM
   TI
   LI
   LO
   TS
CP0483503
N-[5-(2-aminoanilino)-5-oxopentyl]-5-cyclopropyl-2-(1,3-thiazol-2-yl)-1,3-thiazole-4-carboxamide
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C21H23N5O2S2
 1
1
IC50 = 2092.35 nM
   TI
   LI
   LO
   TS
CP0406683
5-cyclopropyl-2-(1,3-thiazol-2-yl)-N-(6,6,6-trifluoro-5-hydroxyhexyl)-1,3-thiazole-4-carboxamide
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C16H18F3N3O2S2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0428637
5-cyclopropyl-N-[4-(hydroxycarbamoylamino)butyl]-2-(1,3-thiazol-2-yl)-1,3-thiazole-4-carboxamide
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C15H19N5O3S2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0477243
5-cyclopropyl-2-(1,3-thiazol-2-yl)-N-(5,5,5-trifluoro-4-oxopentyl)-1,3-thiazole-4-carboxamide
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C15H14F3N3O2S2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0520377
5-cyclopropyl-2-(1,3-thiazol-2-yl)-N-[5-[[3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzoyl]amino]pentyl]-1,3-thiazole-4-carboxamide
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C25H23F3N6O3S2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0003580
Faridak
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C21H23N3O2
 1
1
IC50 = 10390 nM
   TI
   LI
   LO
   TS
CP0444962
5-cyclopropyl-N-[(1S)-1-[4-(hydroxycarbamoyl)phenyl]ethyl]-2-(5-phenyl-1,3-thiazol-2-yl)-1,3-thiazole-4-carboxamide
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C25H22N4O3S2
 1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS