Brief Information of the Cell Line and Protein
Cell Line ID: CL000017 , HeLa
 Cell Line Info 
Synonyms
HELA
Hela
He La
He-La
HeLa-CCL2
Henrietta Lacks cells
Helacyton gartleri
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0030
Protein ID: PT00985 , Cell division cycle 7-related protein kinase
 Protein Info 
Gene Name CDC7
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID O00311
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000017
 Cell Line Info 
 Protein ID: PT00985
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0179612
 Compound Info 
Simurosertib
   Show/Hide
C17H19N5OS
  1
1
IC50 = 17 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0202830
 Compound Info 
6-(5-methyl-1H-pyrazol-4-yl)-2-[(2S)-piperidin-2-yl]-3H-thieno[3,2-d]pyrimidin-4-one;dihydrochloride
   Show/Hide
C15H19Cl2N5OS
  1
1
IC50 = 36 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0238040
 Compound Info 
2-[(2S)-piperidin-2-yl]-6-[5-(trifluoromethyl)-1H-pyrazol-4-yl]-3H-thieno[3,2-d]pyrimidin-4-one;hydrochloride
   Show/Hide
C15H15ClF3N5OS
  1
1
IC50 = 41 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0558430
 Compound Info 
2-(cyclopentylmethyl)-6-(5-methyl-1H-pyrazol-4-yl)-3H-thieno[3,2-d]pyrimidin-4-one
   Show/Hide
C16H18N4OS
  1
1
IC50 = 67 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0248431
 Compound Info 
2-(2-azabicyclo[2.1.1]hexan-1-yl)-6-(5-methyl-1H-pyrazol-4-yl)-3H-thieno[3,2-d]pyrimidin-4-one;dihydrochloride
   Show/Hide
C15H17Cl2N5OS
  1
1
IC50 = 130 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0238038
 Compound Info 
6-(5-methyl-1H-pyrazol-4-yl)-2-(pyrrolidin-1-ylmethyl)-3H-thieno[3,2-d]pyrimidin-4-one
   Show/Hide
C15H17N5OS
  1
1
IC50 = 250 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0931559
 Compound Info 
2-[(Dimethylamino)methyl]-6-(3-methyl-1H-pyrazol-4-yl)thieno[3,2-d]pyrimidin-4(3H)-one dihydrochloride
   Show/Hide
C13H17Cl2N5OS
  1
1
IC50 = 350 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0521699
 Compound Info 
6-(1H-pyrazol-4-yl)-2-(pyrrolidin-1-ylmethyl)-3H-thieno[3,2-d]pyrimidin-4-one
   Show/Hide
C14H15N5OS
  1
1
IC50 > 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0548910
 Compound Info 
6-pyridin-4-yl-2-(pyrrolidin-1-ylmethyl)-3H-thieno[3,2-d]pyrimidin-4-one
   Show/Hide
C16H16N4OS
  1
1
IC50 > 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS