| Compound ID |
Compound Name |
Compound Formula |
|
CP0578736
|
4-[5-chloro-2-[[1-(3,4-dimethoxyphenyl)-2-oxoimidazo[4,5-c]pyridin-3-yl]methyl]indol-1-yl]butanenitrile
Show/Hide
|
C27H24ClN5O3
|
1
|
| 1 |
EC50 = 0.1 nM
|
|
|
|
CP0570828
|
3-[[5-chloro-1-(3-methylsulfonylpropyl)indol-2-yl]methyl]-1-cyclopropylimidazo[4,5-c]pyridin-2-one
Show/Hide
|
C22H23ClN4O3S
|
1
|
| 1 |
EC50 = 0.1995 nM
|
|
|
|
CP0570829
|
4-[5-chloro-2-[(1-cyclopropyl-2-oxoimidazo[4,5-c]pyridin-3-yl)methyl]indol-1-yl]butanenitrile
Show/Hide
|
C22H20ClN5O
|
1
|
| 1 |
EC50 = 0.1995 nM
|
|
|
|
CP0572723
|
4-[5-chloro-2-[[1-(4-methylsulfonylphenyl)-2-oxoimidazo[4,5-c]pyridin-3-yl]methyl]indol-1-yl]butanenitrile
Show/Hide
|
C26H22ClN5O3S
|
1
|
| 1 |
EC50 = 0.1995 nM
|
|
|
|
CP0539190
|
1-cyclopropyl-3-[[1-(4,4,4-trifluorobutyl)pyrrolo[3,2-c]pyridin-2-yl]methyl]imidazo[4,5-c]pyridin-2-one
Show/Hide
|
C21H20F3N5O
|
1
|
| 1 |
EC50 = 0.2512 nM
|
|
|
|
CP0571925
|
3-[[5-chloro-1-(4,4,4-trifluorobutyl)indol-2-yl]methyl]-1-cyclopropylimidazo[4,5-c]pyridin-2-one
Show/Hide
|
C22H20ClF3N4O
|
1
|
| 1 |
EC50 = 0.2512 nM
|
|
|
|
CP0574834
|
4-[5-chloro-2-[[1-(4-methoxy-3-methylphenyl)-2-oxoimidazo[4,5-c]pyridin-3-yl]methyl]indol-1-yl]butanenitrile
Show/Hide
|
C27H24ClN5O2
|
1
|
| 1 |
EC50 = 0.2512 nM
|
|
|
|
CP0576874
|
1-cyclopropyl-3-[[1-(3-methylbutyl)pyrrolo[3,2-c]pyridin-2-yl]methyl]imidazo[4,5-c]pyridin-2-one
Show/Hide
|
C22H25N5O
|
1
|
| 1 |
EC50 = 0.2512 nM
|
|
|
|
CP0483429
|
4-[5-chloro-2-[[1-(4-methoxyphenyl)-2-oxoimidazo[4,5-c]pyridin-3-yl]methyl]indol-1-yl]butanenitrile
Show/Hide
|
C26H22ClN5O2
|
1
|
| 1 |
EC50 = 0.3162 nM
|
|
|
|
CP0526820
|
4-[5-chloro-2-[[1-(3-fluoropyridin-4-yl)-2-oxoimidazo[4,5-c]pyridin-3-yl]methyl]indol-1-yl]butanenitrile
Show/Hide
|
C24H18ClFN6O
|
1
|
| 1 |
EC50 = 0.3162 nM
|
|
|
|
CP0569963
|
3-[[5-chloro-1-(3-methylsulfonylpropyl)indol-2-yl]methyl]-1-(cyclopropylmethyl)imidazo[4,5-c]pyridin-2-one
Show/Hide
|
C23H25ClN4O3S
|
1
|
| 1 |
EC50 = 0.3981 nM
|
|
|
|
CP0572722
|
3-[[5-bromo-1-(3-methylsulfonylpropyl)indol-2-yl]methyl]-1-cyclopropylimidazo[4,5-c]pyridin-2-one
Show/Hide
|
C22H23BrN4O3S
|
1
|
| 1 |
EC50 = 0.3981 nM
|
|
|
|
CP0491708
|
4-[3-[[5-chloro-1-(3-cyanopropyl)indol-2-yl]methyl]-2-oxoimidazo[4,5-c]pyridin-1-yl]benzoic acid
Show/Hide
|
C26H20ClN5O3
|
1
|
| 1 |
EC50 = 0.5012 nM
|
|
|
|
CP0525382
|
4-[3-[[5-chloro-1-(3-cyanopropyl)indol-2-yl]methyl]-2-oxoimidazo[4,5-c]pyridin-1-yl]-N-cyclopropylbenzamide
Show/Hide
|
C29H25ClN6O2
|
1
|
| 1 |
EC50 = 0.5012 nM
|
|
|
|
CP0539189
|
1-cyclopropyl-3-[[1-(4-fluorobutyl)pyrrolo[3,2-c]pyridin-2-yl]methyl]imidazo[4,5-c]pyridin-2-one
Show/Hide
|
C21H22FN5O
|
1
|
| 1 |
EC50 = 0.5012 nM
|
|
|
|
CP0569964
|
Jnj-53718678
Show/Hide
|
C21H20ClF3N4O3S
|
1
|
| 1 |
EC50 = 0.5012 nM
|
|
|
|
CP0575885
|
3-[[5-chloro-1-(3-methylsulfonylpropyl)indol-2-yl]methyl]-1-(1-methylcyclopropyl)imidazo[4,5-c]pyridin-2-one
Show/Hide
|
C23H25ClN4O3S
|
1
|
| 1 |
EC50 = 0.5012 nM
|
|
|
|
CP0483430
|
4-[5-chloro-2-[[1-(2-fluoro-4-methoxyphenyl)-2-oxoimidazo[4,5-c]pyridin-3-yl]methyl]indol-1-yl]butanenitrile
Show/Hide
|
C26H21ClFN5O2
|
1
|
| 1 |
EC50 = 0.631 nM
|
|
|
|
CP0576873
|
3-[[5-chloro-1-(4-fluorobutyl)indol-2-yl]methyl]-1-cyclopropylimidazo[4,5-c]pyridin-2-one
Show/Hide
|
C22H22ClFN4O
|
1
|
| 1 |
EC50 = 0.7943 nM
|
|
|
|
CP0483431
|
4-[5-chloro-2-[[1-(4-methoxy-2-methylphenyl)-2-oxoimidazo[4,5-c]pyridin-3-yl]methyl]indol-1-yl]butanenitrile
Show/Hide
|
C27H24ClN5O2
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0491693
|
3-[[5-chloro-1-(3-methylbutyl)imidazo[4,5-b]pyridin-2-yl]methyl]-1-cyclopropylimidazo[4,5-c]pyridin-2-one
Show/Hide
|
C21H23ClN6O
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0539188
|
1-cyclopropyl-3-[[1-(3-methylsulfonylpropyl)pyrrolo[3,2-c]pyridin-2-yl]methyl]imidazo[4,5-c]pyridin-2-one
Show/Hide
|
C21H23N5O3S
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0571926
|
3-[[5-chloro-1-(4,4,4-trifluorobutyl)imidazo[4,5-b]pyridin-2-yl]methyl]-1-cyclopropylimidazo[4,5-c]pyridin-2-one
Show/Hide
|
C20H18ClF3N6O
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0517302
|
4-[5-chloro-2-[[2-oxo-1-[4-(trifluoromethoxy)phenyl]imidazo[4,5-c]pyridin-3-yl]methyl]indol-1-yl]butanenitrile
Show/Hide
|
C26H19ClF3N5O2
|
1
|
| 1 |
EC50 = 1.259 nM
|
|
|
|
CP0539187
|
3-[[5-bromo-1-(4-hydroxybutyl)indol-2-yl]methyl]-1-cyclopropylimidazo[4,5-c]pyridin-2-one
Show/Hide
|
C22H23BrN4O2
|
1
|
| 1 |
EC50 = 1.259 nM
|
|
|
|
CP0570832
|
4-[5-chloro-2-[[1-(4-methylphenyl)-2-oxoimidazo[4,5-c]pyridin-3-yl]methyl]indol-1-yl]butanenitrile
Show/Hide
|
C26H22ClN5O
|
1
|
| 1 |
EC50 = 1.259 nM
|
|
|
|
CP0517303
|
4-[5-chloro-2-[[1-(1,3-oxazol-2-yl)-2-oxoimidazo[4,5-c]pyridin-3-yl]methyl]indol-1-yl]butanenitrile
Show/Hide
|
C22H17ClN6O2
|
1
|
| 1 |
EC50 = 1.585 nM
|
|
|
|
CP0525384
|
4-[5-chloro-2-[[1-(1-methylpyrazol-3-yl)-2-oxoimidazo[4,5-c]pyridin-3-yl]methyl]indol-1-yl]butanenitrile
Show/Hide
|
C23H20ClN7O
|
1
|
| 1 |
EC50 = 1.585 nM
|
|
|
|
CP0539185
|
1-cyclopropyl-3-[[1-(4-hydroxybutyl)pyrrolo[3,2-c]pyridin-2-yl]methyl]imidazo[4,5-c]pyridin-2-one
Show/Hide
|
C21H23N5O2
|
1
|
| 1 |
EC50 = 1.585 nM
|
|
|
|
CP0539191
|
3-[[5-chloro-1-(3-methylsulfonylpropyl)indol-2-yl]methyl]-1-propan-2-ylimidazo[4,5-c]pyridin-2-one
Show/Hide
|
C22H25ClN4O3S
|
1
|
| 1 |
EC50 = 1.585 nM
|
|
|
|
CP0574981
|
3-[[5-chloro-1-(4-hydroxy-4-methylpentyl)imidazo[4,5-b]pyridin-2-yl]methyl]-1-cyclopropylimidazo[4,5-c]pyridin-2-one
Show/Hide
|
C22H25ClN6O2
|
1
|
| 1 |
EC50 = 1.585 nM
|
|
|
|
CP0575886
|
3-[[5-chloro-1-(3-methylsulfonylpropyl)indol-2-yl]methyl]-1-(1-methylsulfonylazetidin-3-yl)imidazo[4,5-c]pyridin-2-one
Show/Hide
|
C23H26ClN5O5S2
|
1
|
| 1 |
EC50 = 1.585 nM
|
|
|
|
CP0577835
|
3-[[5-chloro-1-(4-hydroxy-4-methylpentyl)indol-2-yl]methyl]-1-cyclopropylimidazo[4,5-c]pyridin-2-one
Show/Hide
|
C24H27ClN4O2
|
1
|
| 1 |
EC50 = 1.585 nM
|
|
|
|
CP0477752
|
2-[3-[[5-chloro-1-(3-methylsulfonylpropyl)indol-2-yl]methyl]-2-oxoimidazo[4,5-c]pyridin-1-yl]acetonitrile
Show/Hide
|
C21H20ClN5O3S
|
1
|
| 1 |
EC50 = 1.995 nM
|
|
|
|
CP0479652
|
3-[[5-chloro-1-(4-fluorobutyl)imidazo[4,5-b]pyridin-2-yl]methyl]-1-cyclopropylimidazo[4,5-c]pyridin-2-one
Show/Hide
|
C20H20ClFN6O
|
1
|
| 1 |
EC50 = 1.995 nM
|
|
|
|
CP0577834
|
3-[[5-chloro-1-(4-hydroxybutyl)indol-2-yl]methyl]-1-cyclopropylimidazo[4,5-c]pyridin-2-one
Show/Hide
|
C22H23ClN4O2
|
1
|
| 1 |
EC50 = 1.995 nM
|
|
|
|
CP0483428
|
3-[[5-chloro-1-(3-methylsulfonylpropyl)indol-2-yl]methyl]-1-(oxetan-3-yl)imidazo[4,5-c]pyridin-2-one
Show/Hide
|
C22H23ClN4O4S
|
1
|
| 1 |
EC50 = 2.512 nM
|
|
|
|
CP0483432
|
4-[5-chloro-2-[(2-oxo-1-pyridin-4-ylimidazo[4,5-c]pyridin-3-yl)methyl]indol-1-yl]butanenitrile
Show/Hide
|
C24H19ClN6O
|
1
|
| 1 |
EC50 = 2.512 nM
|
|
|
|
CP0564334
|
4-[5-chloro-2-[(1-cyclopropyl-2-oxoimidazo[4,5-c]pyridin-3-yl)methyl]indol-1-yl]-N'-hydroxybutanimidamide
Show/Hide
|
C22H23ClN6O2
|
1
|
| 1 |
EC50 = 2.512 nM
|
|
|
|
CP0571955
|
1-tert-butyl-3-[[5-chloro-1-(3-methylsulfonylpropyl)indol-2-yl]methyl]imidazo[4,5-c]pyridin-2-one
Show/Hide
|
C23H27ClN4O3S
|
1
|
| 1 |
EC50 = 2.512 nM
|
|
|
|
CP0483427
|
3-[[5-chloro-1-(3-methylsulfonylpropyl)imidazo[4,5-b]pyridin-2-yl]methyl]-1-cyclopropylimidazo[4,5-c]pyridin-2-one
Show/Hide
|
C20H21ClN6O3S
|
1
|
| 1 |
EC50 = 3.981 nM
|
|
|
|
CP0570827
|
1-cyclopropyl-3-[[5-fluoro-1-(3-methylsulfonylpropyl)indol-2-yl]methyl]imidazo[4,5-c]pyridin-2-one
Show/Hide
|
C22H23FN4O3S
|
1
|
| 1 |
EC50 = 3.981 nM
|
|
|
|
CP0526818
|
3-[[5-chloro-1-(3-methylsulfonylpropyl)indol-2-yl]methyl]-1-(1,1,1-trifluoropropan-2-yl)imidazo[4,5-c]pyridin-2-one
Show/Hide
|
C22H22ClF3N4O3S
|
1
|
| 1 |
EC50 = 5.012 nM
|
|
|
|
CP0570831
|
3-[[5-chloro-1-(4-hydroxybutyl)imidazo[4,5-b]pyridin-2-yl]methyl]-1-cyclopropylimidazo[4,5-c]pyridin-2-one
Show/Hide
|
C20H21ClN6O2
|
1
|
| 1 |
EC50 = 5.012 nM
|
|
|
|
CP0516574
|
3-[[5-chloro-1-(3-morpholin-4-ylpropyl)indol-2-yl]methyl]-1-cyclopropylimidazo[4,5-c]pyridin-2-one
Show/Hide
|
C25H28ClN5O2
|
1
|
| 1 |
EC50 = 6.31 nM
|
|
|
|
CP0526819
|
4-[5-chloro-2-[(2-oxo-1-pyrimidin-2-ylimidazo[4,5-c]pyridin-3-yl)methyl]indol-1-yl]butanenitrile
Show/Hide
|
C23H18ClN7O
|
1
|
| 1 |
EC50 = 6.31 nM
|
|
|
|
CP0036151
|
BMS-433771
Show/Hide
|
C21H23N5O2
|
1
|
| 1 |
EC50 = 7.943 nM
|
|
|
|
CP0516575
|
3-[[5-chloro-1-(3-methylsulfonylpropyl)indol-2-yl]methyl]-1H-imidazo[4,5-c]pyridin-2-one
Show/Hide
|
C19H19ClN4O3S
|
1
|
| 1 |
EC50 = 7.943 nM
|
|
|
|
CP0572731
|
1-cyclopropyl-3-[[1-(3-methylsulfonylpropyl)-5-(trifluoromethyl)indol-2-yl]methyl]imidazo[4,5-c]pyridin-2-one
Show/Hide
|
C23H23F3N4O3S
|
1
|
| 1 |
EC50 = 7.943 nM
|
|
|
|
CP0574831
|
1-cyclopropyl-3-[[1-(3-methylbutyl)imidazo[4,5-b]pyridin-2-yl]methyl]imidazo[4,5-c]pyridin-2-one
Show/Hide
|
C21H24N6O
|
1
|
| 1 |
EC50 = 7.943 nM
|
|
|
|
CP0437408
|
1-cyclopropyl-3-[[1-(4-hydroxybutyl)imidazo[4,5-b]pyridin-2-yl]methyl]imidazo[4,5-c]pyridin-2-one
Show/Hide
|
C20H22N6O2
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0525383
|
4-[5-chloro-2-[(2-oxo-1-pyrimidin-4-ylimidazo[4,5-c]pyridin-3-yl)methyl]indol-1-yl]butanenitrile
Show/Hide
|
C23H18ClN7O
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0569962
|
4-[5-chloro-2-[(1-cyclopropyl-2-oxoimidazo[4,5-c]pyridin-3-yl)methyl]imidazo[4,5-b]pyridin-1-yl]butanenitrile
Show/Hide
|
C20H18ClN7O
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0574832
|
1-cyclopropyl-3-[[1-(3-methylsulfonylpropyl)indol-2-yl]methyl]imidazo[4,5-c]pyridin-2-one
Show/Hide
|
C22H24N4O3S
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0572721
|
1-cyclopropyl-3-[[5-fluoro-1-(4-hydroxybutyl)indol-2-yl]methyl]imidazo[4,5-c]pyridin-2-one
Show/Hide
|
C22H23FN4O2
|
1
|
| 1 |
EC50 = 15.85 nM
|
|
|
|
CP0526815
|
1-cyclopropyl-3-[[1-(3-methylbutyl)imidazo[4,5-c]pyridin-2-yl]methyl]imidazo[4,5-c]pyridin-2-one
Show/Hide
|
C21H24N6O
|
1
|
| 1 |
EC50 = 31.62 nM
|
|
|
|
CP0537857
|
1-(azetidin-3-yl)-3-[[5-chloro-1-(3-methylsulfonylpropyl)indol-2-yl]methyl]imidazo[4,5-c]pyridin-2-one
Show/Hide
|
C22H24ClN5O3S
|
1
|
| 1 |
EC50 = 31.62 nM
|
|
|
|
CP0526816
|
1-cyclopropyl-3-[[1-(4-hydroxybutyl)-5-methoxyindol-2-yl]methyl]imidazo[4,5-c]pyridin-2-one
Show/Hide
|
C23H26N4O3
|
1
|
| 1 |
EC50 = 39.81 nM
|
|
|
|
CP0570826
|
1-cyclopropyl-3-[[1-(4-hydroxybutyl)imidazo[4,5-c]pyridin-2-yl]methyl]imidazo[4,5-c]pyridin-2-one
Show/Hide
|
C20H22N6O2
|
1
|
| 1 |
EC50 = 50.12 nM
|
|
|
|
CP0571954
|
4-[5-chloro-2-[(1-cyclopropyl-2-oxoimidazo[4,5-c]pyridin-3-yl)methyl]indol-1-yl]butanamide
Show/Hide
|
C22H22ClN5O2
|
1
|
| 1 |
EC50 = 50.12 nM
|
|
|
|
CP0569960
|
1-cyclopropyl-3-[[3-(3-methylbutyl)imidazo[4,5-c]pyridin-2-yl]methyl]imidazo[4,5-c]pyridin-2-one
Show/Hide
|
C21H24N6O
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0516573
|
3-[[6-chloro-1-(4-hydroxybutyl)indol-2-yl]methyl]-1-cyclopropylimidazo[4,5-c]pyridin-2-one
Show/Hide
|
C22H23ClN4O2
|
1
|
| 1 |
EC50 = 125.89 nM
|
|
|
|
CP0569961
|
1-cyclopropyl-3-[[1-(4-hydroxybutyl)pyrrolo[2,3-c]pyridin-2-yl]methyl]imidazo[4,5-c]pyridin-2-one
Show/Hide
|
C21H23N5O2
|
1
|
| 1 |
EC50 = 125.89 nM
|
|
|
|
CP0483426
|
1-cyclopropyl-3-[[1-(4-hydroxybutyl)pyrrolo[3,2-b]pyridin-2-yl]methyl]imidazo[4,5-c]pyridin-2-one
Show/Hide
|
C21H23N5O2
|
1
|
| 1 |
EC50 = 158.49 nM
|
|
|
|
CP0570830
|
4-[5-chloro-2-[(1-cyclopropyl-2-oxoimidazo[4,5-c]pyridin-3-yl)methyl]indol-1-yl]butanoic acid
Show/Hide
|
C22H21ClN4O3
|
1
|
| 1 |
EC50 = 199.53 nM
|
|
|
|
CP0491694
|
1-cyclopropyl-3-[[1-(3-methylbutyl)indol-2-yl]methyl]imidazo[4,5-c]pyridin-2-one
Show/Hide
|
C23H26N4O
|
1
|
| 1 |
EC50 = 398.11 nM
|
|
|
|
CP0525381
|
1-cyclopropyl-3-[[3-(3-methylbutyl)imidazo[4,5-b]pyridin-2-yl]methyl]imidazo[4,5-c]pyridin-2-one
Show/Hide
|
C21H24N6O
|
1
|
| 1 |
EC50 = 1258.93 nM
|
|
|
|
CP0539186
|
1-cyclopropyl-3-[[1-(3-methylbutyl)pyrrolo[2,3-b]pyridin-2-yl]methyl]imidazo[4,5-c]pyridin-2-one
Show/Hide
|
C22H25N5O
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
