General Information of the Compound
Compound ID
CP0572723
Compound Name
4-[5-chloro-2-[[1-(4-methylsulfonylphenyl)-2-oxoimidazo[4,5-c]pyridin-3-yl]methyl]indol-1-yl]butanenitrile
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Structure
Formula
C26H22ClN5O3S
Molecular Weight
520.014
Canonical SMILES
CS(=O)(=O)c1ccc(cc1)-n1c2ccncc2n(Cc2cc3cc(Cl)ccc3n2CCCC#N)c1=O
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InChI
InChI=1S/C26H22ClN5O3S/c1-36(34,35)22-7-5-20(6-8-22)32-24-10-12-29-16-25(24)31(26(32)33)17-21-15-18-14-19(27)4-9-23(18)30(21)13-3-2-11-28/h4-10,12,14-16H,2-3,13,17H2,1H3
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InChIKey
KUOYCOBLIGDUFP-UHFFFAOYSA-N
Physicochemical Property
logP
4.55088
Rotatable Bonds
7
Heavy Atom Count
36
Polar Areas
102.68
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
8
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 118023792
ChEMBL ID
CHEMBL4647497
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00459, Fusion glycoprotein F0
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  1
1
EC50 = 0.1995 nM
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Cell Viability or Cytotoxicity Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  1
1
CC50 > 50000 nM
   TI
   LI
   LO
   TS