| Compound ID |
Compound Name |
Compound Formula |
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CP0351090
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(2R)-3-[(2S)-6-(2,5-difluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]-2-methylpropanoic acid
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C25H20F5NO5S
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1
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| 1 |
EC50 = 3 nM
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CP0546383
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3-[(2S)-6-(3-chlorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
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|
C24H19ClF3NO5S
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1
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| 1 |
EC50 = 3 nM
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|
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CP0557795
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(2S)-3-[(2S)-6-(2,5-difluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]-2-methylpropanoic acid
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C25H20F5NO5S
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1
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| 1 |
EC50 = 4 nM
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CP0527539
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4-[[(2S)-6-(2,5-difluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]methyl]oxane-4-carboxylic acid
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|
C28H24F5NO6S
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1
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| 1 |
EC50 = 5 nM
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|
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CP0420013
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3-[[(2S)-6-[3-(difluoromethoxy)-5-fluorophenyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]methyl]oxetane-3-carboxylic acid
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|
C27H21F6NO7S
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1
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| 1 |
EC50 = 6 nM
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|
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CP0539745
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3-[(2S)-6-(3-fluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
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|
C24H19F4NO5S
|
1
|
| 1 |
EC50 = 6 nM
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|
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CP0552379
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3-[(2S)-6-(3-fluoro-5-methoxyphenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
Show/Hide
|
C25H21F4NO6S
|
1
|
| 1 |
EC50 = 6 nM
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|
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CP0471267
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3-[(2S)-6-(3-methoxyphenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
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|
C25H22F3NO6S
|
1
|
| 1 |
EC50 = 8 nM
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|
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CP0534099
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3-[(2S)-6-(2,5-difluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
Show/Hide
|
C24H18F5NO5S
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1
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| 1 |
EC50 = 8 nM
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|
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CP0534361
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4-[[(2S)-6-[3-(difluoromethoxy)-5-fluorophenyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]methyl]oxane-4-carboxylic acid
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|
C29H25F6NO7S
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1
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| 1 |
EC50 = 8 nM
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|
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CP0552384
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3-[(2S)-6-(2-chlorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
Show/Hide
|
C24H19ClF3NO5S
|
1
|
| 1 |
EC50 = 9 nM
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|
|
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CP0471269
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3-[[(2S)-6-(2,5-difluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]methyl]oxetane-3-carboxylic acid
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|
C26H20F5NO6S
|
1
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| 1 |
EC50 = 10 nM
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CP0487451
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3-[(2S)-6-(3-chloro-2-fluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]-2,2-dimethylpropanoic acid
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|
C26H22ClF4NO5S
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1
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| 1 |
EC50 = 10 nM
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|
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CP0564257
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3-[(2S)-6-[3-(difluoromethoxy)phenyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
Show/Hide
|
C25H20F5NO6S
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
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CP0060756
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3-[(2S)-6-[3-(difluoromethoxy)-5-fluorophenyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]-2,2-dimethylpropanoic acid
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|
C27H23F6NO6S
|
1
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| 1 |
EC50 = 13 nM
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|
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CP0471264
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(2S)-4-[(2S)-6-(2,5-difluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]-2-hydroxybutanoic acid
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|
C25H20F5NO6S
|
1
|
| 1 |
EC50 = 13 nM
|
|
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CP0471273
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3-[(2S)-6-(2,5-difluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]-2,2-dimethylpropanoic acid
Show/Hide
|
C26H22F5NO5S
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1
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| 1 |
EC50 = 13 nM
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|
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CP0549139
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3-[(2S)-6-(3,5-difluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
Show/Hide
|
C24H18F5NO5S
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1
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| 1 |
EC50 = 14 nM
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|
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CP0471268
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3-[(2S)-6-(2-chloro-3,5-difluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
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|
C24H17ClF5NO5S
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1
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| 1 |
EC50 = 22 nM
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CP0138560
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4-[[(2S)-6-(3-chloro-2-fluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]methyl]oxane-4-carboxylic acid
Show/Hide
|
C28H24ClF4NO6S
|
1
|
| 1 |
EC50 = 24 nM
|
|
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CP0420011
|
3-[(2S)-6-[3-(difluoromethoxy)-5-fluorophenyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
Show/Hide
|
C25H19F6NO6S
|
1
|
| 1 |
EC50 = 24 nM
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CP0189595
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3-[(2S)-6-(4-chlorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
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|
C24H19ClF3NO5S
|
1
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| 1 |
EC50 = 27 nM
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CP0550333
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3-[(2S)-6-[(E)-2-(2-chloro-6-fluorophenyl)ethenyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
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|
C26H20ClF4NO5S
|
1
|
| 1 |
EC50 = 33 nM
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|
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CP0138557
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3-[(2S)-6-[(E)-2-(2-chloro-6-fluorophenyl)prop-1-enyl]-4-[[2-(2-hydroxyethoxy)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl]sulfonyl]-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
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|
C29H31ClFN3O7S
|
1
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| 1 |
EC50 = 36 nM
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CP0138638
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3-[(2S)-6-(4-propan-2-ylphenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
Show/Hide
|
C27H26F3NO5S
|
1
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| 1 |
EC50 = 42 nM
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CP0189594
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3-[(2S)-6-[(E)-2-(2-chlorophenyl)prop-1-enyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
Show/Hide
|
C27H23ClF3NO5S
|
1
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| 1 |
EC50 = 46 nM
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CP0138637
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3-[(2S)-6-[(E)-2-[2-chloro-6-(trifluoromethyl)phenyl]ethenyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
Show/Hide
|
C27H20ClF6NO5S
|
1
|
| 1 |
EC50 = 68 nM
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CP0550332
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3-[(2S)-6-[(E)-2-(2-chloro-6-fluorophenyl)prop-1-enyl]-4-[4-fluoro-3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
Show/Hide
|
C27H21ClF5NO5S
|
1
|
| 1 |
EC50 = 85 nM
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CP0534360
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3-[(2S)-6-[(E)-2-phenylprop-1-enyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
Show/Hide
|
C27H24F3NO5S
|
1
|
| 1 |
EC50 = 95 nM
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CP0487452
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3-[(2S)-6-[(E)-2-(2-chloro-6-fluorophenyl)prop-1-enyl]-4-(4-fluoro-3-methoxyphenyl)sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
Show/Hide
|
C27H24ClF2NO6S
|
1
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| 1 |
EC50 = 105 nM
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CP0552372
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3-[(2S)-6-[(E)-2-[2-(trifluoromethyl)phenyl]prop-1-enyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
Show/Hide
|
C28H23F6NO5S
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1
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| 1 |
EC50 = 108 nM
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CP0534098
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3-[(2S)-6-[(E)-2-(2-methylphenyl)prop-1-enyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
Show/Hide
|
C28H26F3NO5S
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1
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| 1 |
EC50 = 112 nM
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CP0552370
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(2R)-4-[(2S)-6-(2,5-difluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]-2-hydroxybutanoic acid
Show/Hide
|
C25H20F5NO6S
|
1
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| 1 |
EC50 = 119.7 nM
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CP0552378
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3-[(2S)-6-(2-chloro-5-fluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
Show/Hide
|
C24H18ClF4NO5S
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1
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| 1 |
EC50 = 145 nM
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CP0562991
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[3-[[(2S)-6-bromo-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]methyl]oxetan-3-yl]methanol
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|
C20H19BrF3NO5S
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1
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| 1 |
EC50 = 159 nM
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CP0471271
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3-[(2S)-6-[(E)-2-(2-chloro-6-fluorophenyl)prop-1-enyl]-4-[3-(difluoromethoxy)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
Show/Hide
|
C27H23ClF3NO6S
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1
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| 1 |
EC50 = 195 nM
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CP0058361
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CHEMBL3774855
Show/Hide
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C28H39N5O2
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1
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| 1 |
EC50 = 200 nM
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CP0471263
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3-[(2S)-6-[(E)-2-(2-chloro-6-fluorophenyl)prop-1-enyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
Show/Hide
|
C27H22ClF4NO5S
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1
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| 1 |
EC50 = 223 nM
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CP0553547
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3-[(2S)-6-(2-chloro-3-fluorophenyl)-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
Show/Hide
|
C24H18ClF4NO5S
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1
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| 1 |
EC50 = 262 nM
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CP0552371
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3-[(2S)-6-[(E)-2-(2-chloro-6-fluorophenyl)prop-1-enyl]-4-(3-cyclopropyl-4-fluorophenyl)sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
Show/Hide
|
C29H26ClF2NO5S
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1
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| 1 |
EC50 = 269 nM
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CP0546643
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3-[(2S)-6-[(E)-2-(4-chloro-2-fluorophenyl)ethenyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
Show/Hide
|
C26H20ClF4NO5S
|
1
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| 1 |
EC50 = 342 nM
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CP0527541
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3-[(2S)-6-[(E)-2-(2,6-dichlorophenyl)prop-1-enyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
Show/Hide
|
C27H22Cl2F3NO5S
|
1
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| 1 |
EC50 = 435 nM
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CP0360184
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2-[[5-(2,3-dihydro-1H-inden-2-yl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-N-naphthalen-1-ylacetamide
Show/Hide
|
C25H24N4OS
|
1
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| 1 |
EC50 = 850 nM
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CP0546382
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3-[(2S)-6-[(E)-2-(4-methylphenyl)ethenyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
Show/Hide
|
C27H24F3NO5S
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1
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| 1 |
EC50 = 1076 nM
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CP0546458
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3-[(2S)-6-[3-(2-hydroxyethoxy)phenyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
Show/Hide
|
C26H24F3NO7S
|
1
|
| 1 |
EC50 > 10000 nM
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