Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[(2S)-6-[(E)-2-(4-chloro-2-fluorophenyl)ethenyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]propanoic acid
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 PubChem ID
CID: 129278604
Canonical SMILES
OC(=O)CC[C@H]1CN(c2cc(\C=C\c3ccc(Cl)cc3F)ccc2O1)S(=O)(=O)c1cccc(c1)C(F)(F)F
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Compound Formula C26H20ClF4NO5S
Compound Structure
Protein Name
 Protein Info 
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
EC50 = 342 nM
   TI
   LI
   LO
   TS