| Compound ID |
Compound Name |
Compound Formula |
|
CP0011047
|
N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihydropyrrolo[1,2-a]benzimidazol-7-yl)pyrimidin-2-amine
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|
C28H32F2N8
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0014062
|
4-(1-ethyl-5-fluoro-2,3-dihydro-1H-pyrrolo[1,2-a]benzimidazol-7-yl)-5-fluoro-N-[5-[(4-methylpiperazin-1-yl)methyl]pyridin-2-yl]pyrimidin-2-amine
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|
C27H30F2N8
|
1
|
| 1 |
IC50 = 2.4 nM
|
|
|
|
CP0013121
|
5-Fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihydro-1H-benzo[d]pyrrolo[1,2-a]imidazol-7-yl)-N-(5-(piperazin-1-ylmethyl)pyridin-2-yl)pyrimidin-2-amine
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|
C26H28F2N8
|
1
|
| 1 |
IC50 = 3.7 nM
|
|
|
|
CP0005813
|
5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihydropyrrolo[1,2-a]benzimidazol-7-yl)-N-[5-[(4-methylpiperazin-1-yl)methyl]pyridin-2-yl]pyrimidin-2-amine
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|
C27H30F2N8
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0001256
|
Abemaciclib
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|
C27H32F2N8
|
1
|
| 1 |
IC50 = 7.8 nM
|
|
|
|
CP0013850
|
5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihydropyrrolo[1,2-a]benzimidazol-7-yl)-N-[5-[[4-(2-fluoroethyl)piperazin-1-yl]methyl]pyridin-2-yl]pyrimidin-2-amine
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|
C28H31F3N8
|
1
|
| 1 |
IC50 = 11.2 nM
|
|
|
|
CP0014063
|
5-fluoro-4-(5-fluoro-1-methyl-2,3-dihydro-1H-pyrrolo[1,2-a]benzimidazol-7-yl)-N-[5-[(4-propan-2-ylpiperazin-1-yl)methyl]pyridin-2-yl]pyrimidin-2-amine
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|
C28H32F2N8
|
1
|
| 1 |
IC50 = 12.7 nM
|
|
|
|
CP0005460
|
4-(1,1-dimethyl-2,3-dihydropyrrolo[1,2-a]benzimidazol-7-yl)-N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoropyrimidin-2-amine
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|
C28H33FN8
|
1
|
| 1 |
IC50 = 15.8 nM
|
|
|
|
CP0011046
|
N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-4-(5-fluoro-1,1-dimethyl-2,3-dihydropyrrolo[1,2-a]benzimidazol-7-yl)pyrimidin-2-amine
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|
C28H33FN8
|
1
|
| 1 |
IC50 = 17.4 nM
|
|
|
|
CP0012486
|
5-Fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihydro-1H-benzo[d]pyrrolo[1,2-a]imidazol-7-yl)-N-(6-m ethyl-5-(piperazin-1-ylmethyl)pyridin-2-yl)pyrimidin-2-amine
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|
C27H30F2N8
|
1
|
| 1 |
IC50 = 18.7 nM
|
|
|
|
CP0013120
|
N-[5-[(4-cyclopropylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihydropyrrolo[1,2-a]benzimidazol-7-yl)pyrimidin-2-amine
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|
C29H32F2N8
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0006215
|
4-(1-ethyl-5-fluoro-2,3-dihydro-1H-pyrrolo[1,2-a]benzimidazol-7-yl)-N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoropyrimidin-2-amine
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|
C28H32F2N8
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0006216
|
N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(5-fluoro-1-methyl-2,3-dihydro-1H-pyrrolo[1,2-a]benzimidazol-7-yl)pyrimidin-2-amine
Show/Hide
|
C27H30F2N8
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0005812
|
N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(5-fluoro-2,2-dimethyl-1,3-dihydropyrrolo[1,2-a]benzimidazol-7-yl)pyrimidin-2-amine
Show/Hide
|
C28H32F2N8
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0006218
|
N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(6-fluoro-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-8-yl)pyrimidin-2-amine
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|
C27H30F2N8
|
1
|
| 1 |
IC50 = 45.6 nM
|
|
|
|
CP0013849
|
N-[5-[(4-ethylpiperazin-1-yl)methyl]-6-methylpyridin-2-yl]-5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihydropyrrolo[1,2-a]benzimidazol-7-yl)pyrimidin-2-amine
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|
C29H34F2N8
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0012485
|
N-[5-[(4-ethylpiperazin-1-yl)methyl]-6-methylpyridin-2-yl]-5-fluoro-4-(5-fluoro-1-methyl-2,3-dihydro-1H-pyrrolo[1,2-a]benzimidazol-7-yl)pyrimidin-2-amine
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|
C28H32F2N8
|
1
|
| 1 |
IC50 = 178 nM
|
|
|
|
CP0013122
|
N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(5-fluoro-2,3-dihydro-1H-pyrrolo[1,2-a]benzimidazol-7-yl)pyrimidin-2-amine
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|
C26H28F2N8
|
1
|
| 1 |
IC50 = 244.1 nM
|
|
|
|
CP0014064
|
N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(4-fluoro-7,8,9,10-tetrahydro-6H-azepino[1,2-a]benzimidazol-2-yl)pyrimidin-2-amine
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|
C28H32F2N8
|
1
|
| 1 |
IC50 = 247.8 nM
|
|
|
|
CP0011045
|
5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihydropyrrolo[1,2-a]benzimidazol-7-yl)-N-[6-methyl-5-[(4-methylpiperazin-1-yl)methyl]pyridin-2-yl]pyrimidin-2-amine
Show/Hide
|
C28H32F2N8
|
1
|
| 1 |
IC50 = 271 nM
|
|
|
|
CP0014354
|
5-fluoro-4-(5-fluoro-1-methyl-2,3-dihydro-1H-pyrrolo[1,2-a]benzimidazol-7-yl)-N-[5-[(4-methylpiperazin-1-yl)methyl]pyridin-2-yl]pyrimidin-2-amine
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|
C26H28F2N8
|
1
|
| 1 |
IC50 = 275 nM
|
|
|
|
CP0006217
|
4-(2-ethyl-5-fluoro-2,3-dihydro-1H-pyrrolo[1,2-a]benzimidazol-7-yl)-N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoropyrimidin-2-amine
Show/Hide
|
C28H32F2N8
|
1
|
| 1 |
IC50 = 339 nM
|
|
|
|
CP0013119
|
N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(5-fluoro-2-methyl-2,3-dihydro-1H-pyrrolo[1,2-a]benzimidazol-7-yl)pyrimidin-2-amine
Show/Hide
|
C27H30F2N8
|
1
|
| 1 |
IC50 = 392 nM
|
|
|
|
CP0003415
|
N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-4-(5-fluoro-1-methyl-2,3-dihydro-1H-pyrrolo[1,2-a]benzimidazol-7-yl)pyrimidin-2-amine
Show/Hide
|
C27H31FN8
|
1
|
| 1 |
IC50 = 752 nM
|
|
|
