Brief Information of the Compound and Protein
Compound Name
 Compound Info 
Abemaciclib
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 PubChem ID
CID: 46220502
SID: 96075034
Canonical SMILES
CCN1CCN(Cc2ccc(Nc3ncc(F)c(n3)-c3cc(F)c4nc(C)n(C(C)C)c4c3)nc2)CC1
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Compound Formula C27H32F2N8
Compound Structure
Protein Name
 Protein Info 
Cyclin-dependent kinase 6
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
Uniprot ID
Q00534
Gene Name
CDK6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 7.8 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.9 nM
2 IC50 = 5 nM
3 IC50 = 10 nM