| Compound ID |
Compound Name |
Compound Formula |
|
CP0016974
|
5'-methoxy-6'-(3-pyrrolidin-1-ylpropoxy)spiro[cyclobutane-1,3'-indole]-2'-amine
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|
C19H27N3O2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0474260
|
6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylprop-1-ynyl)quinazolin-4-amine
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|
C28H41N7O
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0467921
|
7-[3-(dimethylamino)propyl]-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine
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|
C26H43N7O
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0517653
|
6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropyl)quinazolin-4-amine
Show/Hide
|
C28H45N7O
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0046275
|
2-cyclohexyl-6-methoxy-N-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine
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|
C30H47N5O2
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0467931
|
2-[3-[6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-4-[(1-methylpiperidin-4-yl)amino]quinazolin-7-yl]propyl-methylamino]ethanol
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|
C27H45N7O2
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0467930
|
6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)-7-(2-piperidin-2-ylethyl)quinazolin-4-amine
Show/Hide
|
C28H45N7O
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0533829
|
7-[3-(dimethylamino)prop-1-ynyl]-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine
Show/Hide
|
C26H39N7O
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0039320
|
7-(3-(dimethylamino)propoxy)-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine
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|
C26H43N7O2
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0467922
|
1-[3-[6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-4-[(1-methylpiperidin-4-yl)amino]quinazolin-7-yl]prop-2-ynyl]pyrrolidin-2-one
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|
C28H39N7O2
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0467932
|
7-(4-aminobut-1-ynyl)-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine
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|
C25H37N7O
|
1
|
| 1 |
IC50 = 107 nM
|
|
|
|
CP0467919
|
7-(1-ethylpiperidin-4-yl)-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine
Show/Hide
|
C28H45N7O
|
1
|
| 1 |
IC50 = 142 nM
|
|
|
|
CP0538107
|
5-amino-N-[6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-4-[(1-methylpiperidin-4-yl)amino]quinazolin-7-yl]pentanamide
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|
C26H42N8O2
|
1
|
| 1 |
IC50 = 163 nM
|
|
|
|
CP0474258
|
2-[3-[6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-4-[(1-methylpiperidin-4-yl)amino]quinazolin-7-yl]prop-2-ynyl-methylamino]ethanol
Show/Hide
|
C27H41N7O2
|
1
|
| 1 |
IC50 = 211 nM
|
|
|
|
CP0531052
|
2-cyclohexyl-7-[3-(dimethylamino)propyl]-6-methoxy-N-(1-propan-2-ylpiperidin-4-yl)quinazolin-4-amine
Show/Hide
|
C28H45N5O
|
1
|
| 1 |
IC50 = 214 nM
|
|
|
|
CP0474261
|
1-[3-[6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-4-[(1-methylpiperidin-4-yl)amino]quinazolin-7-yl]propyl]pyrrolidin-2-one
Show/Hide
|
C28H43N7O2
|
1
|
| 1 |
IC50 = 219 nM
|
|
|
|
CP0467918
|
1-[3-[2-cyclohexyl-6-methoxy-4-[(1-propan-2-ylpiperidin-4-yl)amino]quinazolin-7-yl]prop-2-ynyl]pyrrolidin-2-one
Show/Hide
|
C30H41N5O2
|
1
|
| 1 |
IC50 = 338 nM
|
|
|
|
CP0474249
|
2-cyclohexyl-7-[3-(dimethylamino)prop-1-ynyl]-6-methoxy-N-(1-propan-2-ylpiperidin-4-yl)quinazolin-4-amine
Show/Hide
|
C28H41N5O
|
1
|
| 1 |
IC50 = 358 nM
|
|
|
|
CP0529734
|
6-methoxy-7-[3-(methylamino)prop-1-ynyl]-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine
Show/Hide
|
C25H37N7O
|
1
|
| 1 |
IC50 = 359 nM
|
|
|
|
CP0474255
|
3-amino-N-[6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-4-[(1-methylpiperidin-4-yl)amino]quinazolin-7-yl]propanamide
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|
C24H38N8O2
|
1
|
| 1 |
IC50 = 447 nM
|
|
|
|
CP0467929
|
1-(3-aminopropyl)-3-[6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-4-[(1-methylpiperidin-4-yl)amino]quinazolin-7-yl]urea
Show/Hide
|
C25H41N9O2
|
1
|
| 1 |
IC50 = 648 nM
|
|
|
|
CP0519256
|
3-(dimethylamino)-N-[6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-4-[(1-methylpiperidin-4-yl)amino]quinazolin-7-yl]propanamide
Show/Hide
|
C26H42N8O2
|
1
|
| 1 |
IC50 = 672 nM
|
|
|
|
CP0467935
|
7-ethyl-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine
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|
C23H36N6O
|
1
|
| 1 |
IC50 = 740 nM
|
|
|
|
CP0551657
|
6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)-7-(2-piperidin-4-ylethyl)quinazolin-4-amine
Show/Hide
|
C28H45N7O
|
1
|
| 1 |
IC50 = 1190 nM
|
|
|
|
CP0467915
|
2-cyclohexyl-6-methoxy-7-(4-methylpiperazin-1-yl)-N-(1-propan-2-ylpiperidin-4-yl)quinazolin-4-amine
Show/Hide
|
C28H44N6O
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0531053
|
6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)-7-piperidin-2-ylquinazolin-4-amine
Show/Hide
|
C26H41N7O
|
1
|
| 1 |
IC50 = 1220 nM
|
|
|
|
CP0545901
|
7-(3-aminopropyl)-2-cyclohexyl-6-methoxy-N-(1-propan-2-ylpiperidin-4-yl)quinazolin-4-amine
Show/Hide
|
C26H41N5O
|
1
|
| 1 |
IC50 = 1350 nM
|
|
|
|
CP0467924
|
6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-4-[(1-methylpiperidin-4-yl)amino]quinazoline-7-carboxamide
Show/Hide
|
C22H33N7O2
|
1
|
| 1 |
IC50 = 1630 nM
|
|
|
|
CP0531054
|
6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)-7-propylquinazolin-4-amine
Show/Hide
|
C24H38N6O
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0531057
|
N-(4-aminobutyl)-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-4-[(1-methylpiperidin-4-yl)amino]quinazoline-7-carboxamide
Show/Hide
|
C26H42N8O2
|
1
|
| 1 |
IC50 = 2340 nM
|
|
|
|
CP0467933
|
6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-4-[(1-methylpiperidin-4-yl)amino]-N-(4-pyrrolidin-1-ylbutyl)quinazoline-7-carboxamide
Show/Hide
|
C30H48N8O2
|
1
|
| 1 |
IC50 = 2450 nM
|
|
|
|
CP0519257
|
N-(2-aminoethyl)-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-4-[(1-methylpiperidin-4-yl)amino]quinazoline-7-carboxamide
Show/Hide
|
C24H38N8O2
|
1
|
| 1 |
IC50 = 2540 nM
|
|
|
|
CP0519253
|
7-(3-aminoprop-1-ynyl)-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine
Show/Hide
|
C24H35N7O
|
1
|
| 1 |
IC50 = 3020 nM
|
|
|
|
CP0474259
|
N-[3-[6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-4-[(1-methylpiperidin-4-yl)amino]quinazolin-7-yl]prop-2-ynyl]acetamide
Show/Hide
|
C26H37N7O2
|
1
|
| 1 |
IC50 = 3280 nM
|
|
|
|
CP0561857
|
7-(3-aminopropyl)-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine
Show/Hide
|
C24H39N7O
|
1
|
| 1 |
IC50 = 3580 nM
|
|
|
|
CP0551655
|
6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)-7-(2-pyridin-2-ylethyl)quinazolin-4-amine
Show/Hide
|
C28H39N7O
|
1
|
| 1 |
IC50 = 3640 nM
|
|
|
|
CP0519252
|
2-cyclohexyl-6-fluoro-7-(4-methylpiperazin-1-yl)-N-(1-propan-2-ylpiperidin-4-yl)quinazolin-4-amine
Show/Hide
|
C27H41FN6
|
1
|
| 1 |
IC50 = 4540 nM
|
|
|
|
CP0533828
|
6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)-7-pyridin-2-ylquinazolin-4-amine
Show/Hide
|
C26H35N7O
|
1
|
| 1 |
IC50 = 4780 nM
|
|
|
|
CP0531056
|
2-cyclohexyl-7-[3-(dimethylamino)propyl]-6-ethoxy-N-(1-propan-2-ylpiperidin-4-yl)quinazolin-4-amine
Show/Hide
|
C29H47N5O
|
1
|
| 1 |
IC50 = 6170 nM
|
|
|
|
CP0519259
|
6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)-7-piperidin-3-ylquinazolin-4-amine
Show/Hide
|
C26H41N7O
|
1
|
| 1 |
IC50 = 6840 nM
|
|
|
|
CP0474262
|
N-(3-aminopropyl)-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-4-[(1-methylpiperidin-4-yl)amino]quinazoline-7-carboxamide
Show/Hide
|
C25H40N8O2
|
1
|
| 1 |
IC50 = 7960 nM
|
|
|
|
CP0467926
|
2-cyclohexyl-7-[3-(dimethylamino)propyl]-6-fluoro-N-(1-propan-2-ylpiperidin-4-yl)quinazolin-4-amine
Show/Hide
|
C27H42FN5
|
1
|
| 1 |
IC50 = 9230 nM
|
|
|
|
CP0545902
|
7-(3-aminoprop-1-ynyl)-2-cyclohexyl-6-methoxy-N-(1-propan-2-ylpiperidin-4-yl)quinazolin-4-amine
Show/Hide
|
C26H37N5O
|
1
|
| 1 |
IC50 = 18900 nM
|
|
|
|
CP0519258
|
6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)-7-pyridin-3-ylquinazolin-4-amine
Show/Hide
|
C26H35N7O
|
1
|
| 1 |
IC50 = 19100 nM
|
|
|
|
CP0467923
|
N-[2-(dimethylamino)ethyl]-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-4-[(1-methylpiperidin-4-yl)amino]quinazoline-7-carboxamide
Show/Hide
|
C26H42N8O2
|
1
|
| 1 |
IC50 = 20100 nM
|
|
|
|
CP0529721
|
[6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-4-[(1-methylpiperidin-4-yl)amino]quinazolin-7-yl]-piperazin-1-ylmethanone
Show/Hide
|
C26H40N8O2
|
1
|
| 1 |
IC50 = 81300 nM
|
|
|
