Brief Information of the Compound and Protein
Compound Name
 Compound Info 
7-(3-(dimethylamino)propoxy)-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine
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 PubChem ID
CID: 44251522
SID: 87357279
Canonical SMILES
COc1cc2c(NC3CCN(C)CC3)nc(nc2cc1OCCCN(C)C)N1CCCN(C)CC1
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Compound Formula C26H43N7O2
Compound Structure
Protein Name
 Protein Info 
Histone-lysine N-methyltransferase EHMT2
Protein Classification
Epigenetic regulator
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Protein methyltransferase
Uniprot ID
Q96KQ7
Gene Name
EHMT2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000111 MDA-MB-231
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 > 5000 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 60 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 15 nM
2 IC50 = 43 nM
3 IC50 = 57 nM
4 IC50 = 43000 nM
5 Kd = 23 nM
6 Ki = 2.6 nM