General Information of the Compound
| Compound ID |
CP0467915
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| Compound Name |
2-cyclohexyl-6-methoxy-7-(4-methylpiperazin-1-yl)-N-(1-propan-2-ylpiperidin-4-yl)quinazolin-4-amine
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| Structure |
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| Formula |
C28H44N6O
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| Molecular Weight |
480.701
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| Canonical SMILES |
COc1cc2c(NC3CCN(CC3)C(C)C)nc(nc2cc1N1CCN(C)CC1)C1CCCCC1
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| InChI |
InChI=1S/C28H44N6O/c1-20(2)33-12-10-22(11-13-33)29-28-23-18-26(35-4)25(34-16-14-32(3)15-17-34)19-24(23)30-27(31-28)21-8-6-5-7-9-21/h18-22H,5-17H2,1-4H3,(H,29,30,31)
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| InChIKey |
YIPSBLPVYIUMCM-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02221, Histone-lysine N-methyltransferase EHMT1
Protein ID: PT01566, Histone-lysine N-methyltransferase EHMT2